Sivelestat sodium
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- $19 - $3698
- Product name: Sivelestat sodium
- CAS: 201677-61-4
- MF: C20H25N2NaO8S
- MW: 476.48
- EINECS:
- MDL Number:MFCD01937969
- Synonyms:n-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-(s)-glycine monosodium salt tetrahydrate;Sivelestat sodium;N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-Glycine monosodium salt tetrahydrate;Sivelestat(anhydrous);Glycine, N-[2-[[[4-(2,2-diMethyl-1-oxopropoxy)phenyl]sulfonyl]aMino]benzoyl]-, MonosodiuM salt, tetrahydrate;sodium,2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetate,tetrahydrate;Sivelestat sodium Impurity A;EI546 sodium tetrahydrate
74 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Ark Pharm
- AvaChem
- Biosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Synthonix
- TCI Chemical
Package
- 10mM*1mLinDMSO(Solid+Solvent)
- 5mg
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mg
- 10mM*1mLinDMSO
- 10.00mg
- 25mg
- 50.00mg
- 50mg
- 100.00mg
- 100mg
- 250mg
- 1g
- 5G
- Manufactureraablocks
- Product numberAA002DHM
- Product descriptionGlycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98%
- Packaging100mg
- Price$92
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DHM
- Product descriptionGlycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98%
- Packaging250mg
- Price$179
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DHM
- Product descriptionGlycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 95%
- Packaging1g
- Price$363
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DHM
- Product descriptionGlycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98%
- Packaging25mg
- Price$34
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DHM
- Product descriptionGlycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98%
- Packaging5mg
- Price$29
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002DHM
- Product descriptionGlycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98%
- Packaging1mg
- Price$19
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberX209360
- Product descriptionsodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate tetrahydrate 95%
- Packaging1G
- Price$345
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX209360
- Product descriptionsodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate tetrahydrate 95%
- Packaging5G
- Price$1380
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberX209360
- Product descriptionsodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate tetrahydrate 95%
- Packaging250MG
- Price$120
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberJ98651
- Product descriptionSivelestatsodiumtetrahydrate
- Packaging50mg
- Price$249
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging5mg
- Price$51
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging10mg
- Price$86
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging100mg
- Price$435
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging50mg
- Price$287
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA274870
- Product descriptionSivelestatsodiumtetrahydrate 98+%
- Packaging1g
- Price$3698
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0008936
- Product descriptionSIVELESTAT SODIUM HYDRATE 97.00%
- Packaging5MG
- Price$217.8
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002DHM | Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98% | 100mg | $92 | 2026-05-28 | Buy |
| aablocks | AA002DHM | Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98% | 250mg | $179 | 2026-05-28 | Buy |
| aablocks | AA002DHM | Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 95% | 1g | $363 | 2026-05-28 | Buy |
| aablocks | AA002DHM | Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98% | 25mg | $34 | 2026-05-28 | Buy |
| aablocks | AA002DHM | Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98% | 5mg | $29 | 2026-05-28 | Buy |
| aablocks | AA002DHM | Glycine, N-[2-[[[4-(2,2-dimethyl-1-oxopropoxy)phenyl]sulfonyl]amino]benzoyl]-, monosodium salt, tetrahydrate 98% | 1mg | $19 | 2026-05-28 | Buy |
| ACHEMBLOCK | X209360 | sodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate tetrahydrate 95% | 1G | $345 | 2026-05-27 | Buy |
| ACHEMBLOCK | X209360 | sodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate tetrahydrate 95% | 5G | $1380 | 2026-05-27 | Buy |
| ACHEMBLOCK | X209360 | sodium (2-((4-(pivaloyloxy)phenyl)sulfonamido)benzoyl)glycinate tetrahydrate 95% | 250MG | $120 | 2026-05-27 | Buy |
| AK Scientific | J98651 | Sivelestatsodiumtetrahydrate | 50mg | $249 | 2021-12-16 | Buy |
| Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 5mg | $51 | 2021-12-16 | Buy |
| Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 10mg | $86 | 2021-12-16 | Buy |
| Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 100mg | $435 | 2021-12-16 | Buy |
| Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 50mg | $287 | 2021-12-16 | Buy |
| Ambeed | A274870 | Sivelestatsodiumtetrahydrate 98+% | 1g | $3698 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0008936 | SIVELESTAT SODIUM HYDRATE 97.00% | 5MG | $217.8 | 2021-12-16 | Buy |
Properties
storage temp. :Sealed in dry,Room Temperature
solubility :Soluble in DMSO (up to 20 mg/ml).
form :White solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
InChIKey :YMOIFFHCERRYCO-UHFFFAOYSA-N
SMILES :C(C1C=CC=CC=1NS(C1C=CC(OC(=O)C(C)(C)C)=CC=1)(=O)=O)(=O)NCC(=O)O.[NaH].O
CAS DataBase Reference :201677-61-4(CAS DataBase Reference)
solubility :Soluble in DMSO (up to 20 mg/ml).
form :White solid.
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months
InChIKey :YMOIFFHCERRYCO-UHFFFAOYSA-N
SMILES :C(C1C=CC=CC=1NS(C1C=CC(OC(=O)C(C)(C)C)=CC=1)(=O)=O)(=O)NCC(=O)O.[NaH].O
CAS DataBase Reference :201677-61-4(CAS DataBase Reference)
Safety Information
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Description
Sivelestat sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase (HNE) (IC50 = 44 nM, Ki = 0.2 M). Sivelestat sodium tetrahydrate also effectively inhibits leukocyte elastase derived from hamster, mouse, rabbit and rat (IC50 = 19 to 49 nM). Sivelestat sodium tetrahydrate, even at concentrations of 100 M, does not inhibit plasma kallikrein, plasmin, thrombin, trypsin, pancreas kallikrein, chymotrypsin and cathepsin G. In in-vivo studies, sivelestat sodium tetrahydrate suppressed lung hemorrhage in hamster (ID50 = 82 g/kg) by intratracheal administration and increased skin capillary permeability in guinea pigs (ID50 = 9.6 mg/kg) by intravenous administration, both of which were induced by human neutrophil elastase.More related product prices
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