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ChemicalBook >> CAS DataBase List >> Sofalcone

Sofalcone

Sofalcone price.
  • $11 - $2194.5
  • Product name: Sofalcone
  • CAS: 64506-49-6
  • MF: C27H30O6
  • MW: 450.52
  • EINECS:1308068-626-2
  • MDL Number:MFCD00868207
  • Synonyms:{5-[(3-methyl-2-butenyl)oxy]-2-{p-[(3-methyl-2-butenyl)oxy]cinnamoyl}phenoxy}acetic acid;SOFALCONE;SOFALCONE(2'-ETHOXYCARBONYLMETHOXY-4'-(3-METHYL-2-BUTENYL-OXY)ACETOPHENONE);SOFALCONE JP;SOFALCONE MICROPOWDER;[4,4'-Bis(3-methyl-2-butenyloxy)chalcon-2'-yloxy]acetic acid;[5-[(3-Methyl-2-butenyl)oxy]-2-[3-[4-[(3-methyl-2-butenyl)oxy]phenyl]-1-oxo-2-propenyl]phenoxy]acetic acid;2-[5-[(3-Methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-Methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]acetic Acid
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Brand
  • A2B
  • AHH
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • CSNpharm
  • Medical Isotopes, Inc.
  • TCI Chemical
  • TRC
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 100MG
  • 500mg
  • 10mM*1mLinDMSO(Solution)
  • 250mg
  • 0.5g
  • 1g
  • 2g
  • 5g
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  • 25g
  • 100g
  • 500g
  • ManufacturerA2B
  • Product numberAI54356
  • Product descriptionAcetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97%
  • Packaging10g
  • Price$47
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI54356
  • Product descriptionAcetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97%
  • Packaging1g
  • Price$11
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI54356
  • Product descriptionAcetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97%
  • Packaging5g
  • Price$25
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI54356
  • Product descriptionAcetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97%
  • Packaging25g
  • Price$100
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI54356
  • Product descriptionAcetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97%
  • Packaging100g
  • Price$302
  • Updated2026-05-25
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  • ManufacturerA2B
  • Product numberAI54356
  • Product descriptionAcetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97%
  • Packaging500g
  • Price$1141
  • Updated2026-05-25
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  • ManufacturerAHH
  • Product numberAPI-1768
  • Product descriptionSofalcone 98%
  • Packaging0.5g
  • Price$950
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1768
  • Product descriptionSofalcone 97%
  • Packaging0.5g
  • Price$950
  • Updated2026-05-26
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  • ManufacturerAK Scientific
  • Product numberF958
  • Product descriptionSofalcone
  • Packaging5g
  • Price$504
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberF958
  • Product descriptionSofalcone
  • Packaging1g
  • Price$144
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberF958
  • Product descriptionSofalcone
  • Packaging500mg
  • Price$78
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004205
  • Product descriptionSOFALCONE 95.00%
  • Packaging100MG
  • Price$153.3
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004205
  • Product descriptionSOFALCONE 95.00%
  • Packaging1G
  • Price$721.88
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004205
  • Product descriptionSOFALCONE 95.00%
  • Packaging10G
  • Price$2194.5
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberHY-B2184
  • Product descriptionSofalcone 99.01%
  • Packaging1g
  • Price$137
  • Updated2026-05-26
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  • ManufacturerArctom
  • Product numberHY-B2184
  • Product descriptionSofalcone 99.01%
  • Packaging5g
  • Price$479
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
A2B AI54356 Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97% 10g $47 2026-05-25 Buy
A2B AI54356 Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97% 1g $11 2026-05-25 Buy
A2B AI54356 Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97% 5g $25 2026-05-25 Buy
A2B AI54356 Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97% 25g $100 2026-05-25 Buy
A2B AI54356 Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97% 100g $302 2026-05-25 Buy
A2B AI54356 Acetic acid, 2-[5-[(3-methyl-2-buten-1-yl)oxy]-2-[3-[4-[(3-methyl-2-buten-1-yl)oxy]phenyl]-1-oxo-2-propen-1-yl]phenoxy]- 97% 500g $1141 2026-05-25 Buy
AHH API-1768 Sofalcone 98% 0.5g $950 2021-12-16 Buy
AHH API-1768 Sofalcone 97% 0.5g $950 2026-05-26 Buy
AK Scientific F958 Sofalcone 5g $504 2021-12-16 Buy
AK Scientific F958 Sofalcone 1g $144 2021-12-16 Buy
AK Scientific F958 Sofalcone 500mg $78 2021-12-16 Buy
American Custom Chemicals Corporation API0004205 SOFALCONE 95.00% 100MG $153.3 2021-12-16 Buy
American Custom Chemicals Corporation API0004205 SOFALCONE 95.00% 1G $721.88 2021-12-16 Buy
American Custom Chemicals Corporation API0004205 SOFALCONE 95.00% 10G $2194.5 2021-12-16 Buy
Arctom HY-B2184 Sofalcone 99.01% 1g $137 2026-05-26 Buy
Arctom HY-B2184 Sofalcone 99.01% 5g $479 2026-05-26 Buy

Properties

Melting point :143-144°
Boiling point :478.6°C (rough estimate)
Density :1.1362 (rough estimate)
refractive index :1.4870 (estimate)
storage temp. :2-8°C
solubility :Chloroform (Slightly), Ethyl Acetate (Slightly)
form :Solid
pka :2.98±0.10(Predicted)
color :Light Yellow
InChI :InChI=1S/C27H30O6/c1-19(2)13-15-31-22-8-5-21(6-9-22)7-12-25(28)24-11-10-23(32-16-14-20(3)4)17-26(24)33-18-27(29)30/h5-14,17H,15-16,18H2,1-4H3,(H,29,30)
InChIKey :GFWRVVCDTLRWPK-UHFFFAOYSA-N
SMILES :C(O)(=O)COC1=CC(OC/C=C(\C)/C)=CC=C1C(=O)C=CC1=CC=C(OC/C=C(\C)/C)C=C1
CAS DataBase Reference :64506-49-6(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Sofalcone is an anti-ulcer chalcone derivative. It blocks inflammation by suppressing the production of nitric oxide, TNF-α, and MCP-1 while inducing the expression of heme oxygenase-1 when used at 10-20 μM. Sofalcone (20-50 μM) induces VEGF expression in gastric epithelial cells and promotes gastric ulcer healing following eradication therapy for H. pylori.

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