Streptonigrin
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- $130 - $1752.3
- Product name: Streptonigrin
- CAS: 3930-19-6
- MF: C25H22N4O8
- MW: 506.46
- EINECS:223-501-8
- MDL Number:MFCD00063401
- Synonyms:rufocromomycin;streptonigrin from streptomyces flocculus;Streptonigrin, Streptomyces flocculus;Bruneomycin, Nigrin;5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid;5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid;Abbott Crystalline antibiotic;AO 50165L302
19 prices
Selected condition：
Brand
- aablocks
- ApexBio Technology
- Arctom
- AvaChem
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 2mg
- 2.5mg
- 5mg
- 500??g
- Manufactureraablocks
- Product numberAA00C632
- Product descriptionStreptonigrin ≥95%
- Packaging1mg
- Price$130
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00C632
- Product descriptionStreptonigrin ≥95%
- Packaging5mg
- Price$582
- Updated2026-05-28
- Buy
- ManufacturerApexBio Technology
- Product numberBA1052
- Product descriptionStreptonigrin
- Packaging1mg
- Price$380
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-124586
- Product descriptionStreptonigrin 99.20%
- Packaging500??g
- Price$181
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-124586
- Product descriptionStreptonigrin 99.20%
- Packaging1mg
- Price$276
- Updated2026-05-26
- Buy
- ManufacturerAvaChem
- Product number6992
- Product descriptionStreptonigrin >95%
- Packaging1mg
- Price$180
- Updated2026-05-22
- Buy
- ManufacturerBiosynth
- Product numberFA43266
- Product description5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid
- Packaging2mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA43266
- Product description5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid
- Packaging5mg
- Price$700
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberFA43266
- Product description5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid
- Packaging1mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth
- Product numberETB89379
- Product descriptionSteptonigrin
- Packaging5mg
- Price$1752.3
- Updated2026-06-04
- Buy
- ManufacturerCayman Chemical
- Product number27952
- Product descriptionStreptonigrin ≥95%
- Packaging5mg
- Price$582
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number27952
- Product descriptionStreptonigrin ≥95%
- Packaging1mg
- Price$130
- Updated2026-04-30
- Buy
- ManufacturerChemScene
- Product numberCS-0087029
- Product descriptionStreptonigrin 99.20%
- Packaging1mg
- Price$314
- Updated2026-06-04
- Buy
- ManufacturerChemScene
- Product numberCS-0087029
- Product descriptionStreptonigrin 99.20%
- Packaging500??g
- Price$206
- Updated2026-06-04
- Buy
- ManufacturerSigma-Aldrich
- Product numberS1014
- Product descriptionStreptonigrin from Streptomyces flocculus ≥98%
- Packaging1mg
- Price$130
- Updated2026-04-30
- Buy
- ManufacturerSigma-Aldrich
- Product numberS1014
- Product descriptionStreptonigrin from Streptomyces flocculus ≥98%
- Packaging5mg
- Price$476
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00C632 | Streptonigrin ≥95% | 1mg | $130 | 2026-05-28 | Buy |
| aablocks | AA00C632 | Streptonigrin ≥95% | 5mg | $582 | 2026-05-28 | Buy |
| ApexBio Technology | BA1052 | Streptonigrin | 1mg | $380 | 2026-05-06 | Buy |
| Arctom | HY-124586 | Streptonigrin 99.20% | 500??g | $181 | 2026-05-26 | Buy |
| Arctom | HY-124586 | Streptonigrin 99.20% | 1mg | $276 | 2026-05-26 | Buy |
| AvaChem | 6992 | Streptonigrin >95% | 1mg | $180 | 2026-05-22 | Buy |
| Biosynth | FA43266 | 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid | 2mg | $420 | 2021-12-16 | Buy |
| Biosynth | FA43266 | 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid | 5mg | $700 | 2021-12-16 | Buy |
| Biosynth | FA43266 | 5-Amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxoquinolin-2-yl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid | 1mg | $250 | 2021-12-16 | Buy |
| Biosynth | ETB89379 | Steptonigrin | 5mg | $1752.3 | 2026-06-04 | Buy |
| Cayman Chemical | 27952 | Streptonigrin ≥95% | 5mg | $582 | 2026-04-30 | Buy |
| Cayman Chemical | 27952 | Streptonigrin ≥95% | 1mg | $130 | 2026-04-30 | Buy |
| ChemScene | CS-0087029 | Streptonigrin 99.20% | 1mg | $314 | 2026-06-04 | Buy |
| ChemScene | CS-0087029 | Streptonigrin 99.20% | 500??g | $206 | 2026-06-04 | Buy |
| Sigma-Aldrich | S1014 | Streptonigrin from Streptomyces flocculus ≥98% | 1mg | $130 | 2026-04-30 | Buy |
| Sigma-Aldrich | S1014 | Streptonigrin from Streptomyces flocculus ≥98% | 5mg | $476 | 2026-04-30 | Buy |
Properties
Melting point :301-303℃
Boiling point :595.12°C (rough estimate)
Density :1.4130 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Chloroform:Methanol (1:1): 2 mg/ml
form :A solid
pka :6.2-6.4 (1:1 aq dioxane)
color :Light brown to brown
Merck :13,8907
BRN :599390
InChI :1S/C25H22N4O8/c1-9-14(10-6-8-13(35-2)23(36-3)20(10)30)15(26)19(29-17(9)25(33)34)12-7-5-11-18(28-12)22(32)16(27)24(37-4)21(11)31/h5-8,30H,26-27H2,1-4H3,(H,33,34)
InChIKey :PVYJZLYGTZKPJE-UHFFFAOYSA-N
SMILES :COc1ccc(c(O)c1OC)-c2c(C)c(nc(c2N)-c3ccc4C(=O)C(OC)=C(N)C(=O)c4n3)C(O)=O
Boiling point :595.12°C (rough estimate)
Density :1.4130 (rough estimate)
refractive index :1.6000 (estimate)
storage temp. :2-8°C
solubility :Chloroform:Methanol (1:1): 2 mg/ml
form :A solid
pka :6.2-6.4 (1:1 aq dioxane)
color :Light brown to brown
Merck :13,8907
BRN :599390
InChI :1S/C25H22N4O8/c1-9-14(10-6-8-13(35-2)23(36-3)20(10)30)15(26)19(29-17(9)25(33)34)12-7-5-11-18(28-12)22(32)16(27)24(37-4)21(11)31/h5-8,30H,26-27H2,1-4H3,(H,33,34)
InChIKey :PVYJZLYGTZKPJE-UHFFFAOYSA-N
SMILES :COc1ccc(c(O)c1OC)-c2c(C)c(nc(c2N)-c3ccc4C(=O)C(OC)=C(N)C(=O)c4n3)C(O)=O
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Streptonigrin is a phenylpyridylquinoline originally isolated from S. flocculus with diverse biological activities. Streptonigrin (2.5-12.5 μM) induces DNA cleavage by calf thymus topoisomerase II in a concentration-dependent manner. It induces phage production in S. typhimurium when used at concentrations ranging from 1 to 10 μg/ml. Streptonigrin (10 μg/ml) inhibits DNA synthesis in and reduces survival of S. typhimurium bacteria. Streptonigrin is bactericidal against E. coli in an iron-dependent manner, an effect that is blocked by the iron chelators deferoxamine and orthophenanthroline. Streptonigrin (40 nM) is cytotoxic to human HT-29 colon carcinoma cells but not to BE colon carcinoma cells in which NAD(P)H:quinone oxidoreductase is not expressed. Streptonigrin (0.001-0.1 μg/ml) inhibits mitosis and induces chromatin breaks in human leukocytes in a concentration-dependent manner. In vivo, streptonigrin (0.05 mg/kg, i.p.) increases the mean survival time in rats infected with Rauscher virus.More related product prices
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Suppliers and manufacturers
9ding chemical ( Shanghai) Limited
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Guangzhou Isun Pharmaceutical Co., Ltd
Nanjing Sunlida Biological Technology Co., Ltd.
Shanghai Macklin Biochemical Co.,Ltd.
Sigma-Aldrich
Shanghai YuanYe Biotechnology Co., Ltd.
Shandong Xiya Chemical Co., Ltd.
Chengdu Huachun Technology Co., Ltd
Anhui kuer Bioengineering Co., Ltd