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ChemicalBook >> CAS DataBase List >> Streptozotocin

Streptozotocin

Streptozotocin price.
  • $25 - $1610
  • Product name: Streptozotocin
  • CAS: 18883-66-4
  • MF: C8H15N3O7
  • MW: 265.22
  • EINECS:242-646-8
  • MDL Number:MFCD00006607
  • Synonyms:N-(METHYLNITROSOCARBAMOYL)-A-D-GLUCOSAMINE;N-(METHYLNITROSOCARBAMOYL)-ALPHA-D-GLUCOSAMINE;N-(METHYLNITROSOCARBAMOYL)-ALPHA-GLUCOSAMINE;STREPTOZOTOCIN;2-DEOXY-2-(3-METHYL-3-NITROSOUREIDO)-D-GLUCOPYRANOSE;2-DEOXY-2 [([METHYL-NITROSOAMINO]-CARBONYL)-AMINO]-D-GLUCOPYRANOSE;2-DEOXY-2-[[(METHYLNITROSOAMINO)CARBONYL]AMINO]-D-GLUCOSE;U-9889
33 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • BroadPharm
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 20mg
  • 50mg
  • 10mM(in 1mL DMSO)
  • 100mg
  • 500
  • 100
  • 250mg
  • 500mg
  • 1g
  • 2g
  • 5g
  • 25g
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0046-M250
  • Product descriptionStreptozotocin ≥98%(HPLC)≥75%(αanomer)
  • Packaging250mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1255
  • Product descriptionStreptozocin 98%
  • Packaging25g
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberE301
  • Product descriptionStreptozocin
  • Packaging5g
  • Price$789
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61601
  • Product descriptionStreptozotocin, 97+%
  • Packaging500mg
  • Price$148
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61601
  • Product descriptionStreptozotocin, 97+%
  • Packaging1g
  • Price$274
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4457
  • Product descriptionStreptozocin
  • Packaging100mg
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4457
  • Product descriptionStreptozocin
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4457
  • Product descriptionStreptozocin
  • Packaging500mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN93213
  • Product descriptionStreptozotocin ≥98%
  • Packaging20mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMS07936
  • Product descriptionStreptozocin
  • Packaging250mg
  • Price$62.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMS07936
  • Product descriptionStreptozocin
  • Packaging500mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMS07936
  • Product descriptionStreptozocin
  • Packaging1g
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMS07936
  • Product descriptionStreptozocin
  • Packaging2g
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberMS07936
  • Product descriptionStreptozocin
  • Packaging5G
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-25392
  • Product descriptionStreptozocin
  • Packaging250mg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number13104
  • Product descriptionStreptozotocin ≥95%
  • Packaging50mg
  • Price$25
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0046-M250 Streptozotocin ≥98%(HPLC)≥75%(αanomer) 250mg $55 2021-12-16 Buy
AHH API-1255 Streptozocin 98% 25g $800 2021-12-16 Buy
AK Scientific E301 Streptozocin 5g $789 2021-12-16 Buy
Alfa Aesar J61601 Streptozotocin, 97+% 500mg $148 2024-03-01 Buy
Alfa Aesar J61601 Streptozotocin, 97+% 1g $274 2024-03-01 Buy
ApexBio Technology A4457 Streptozocin 100mg $38 2021-12-16 Buy
ApexBio Technology A4457 Streptozocin 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology A4457 Streptozocin 500mg $70 2021-12-16 Buy
Arctom CFN93213 Streptozotocin ≥98% 20mg $100 2021-12-16 Buy
Biosynth Carbosynth MS07936 Streptozocin 250mg $62.5 2021-12-16 Buy
Biosynth Carbosynth MS07936 Streptozocin 500mg $90 2021-12-16 Buy
Biosynth Carbosynth MS07936 Streptozocin 1g $125 2021-12-16 Buy
Biosynth Carbosynth MS07936 Streptozocin 2g $200 2021-12-16 Buy
Biosynth Carbosynth MS07936 Streptozocin 5G $450 2021-12-16 Buy
BroadPharm BP-25392 Streptozocin 250mg $200 2021-12-16 Buy
Cayman Chemical 13104 Streptozotocin ≥95% 50mg $25 2024-03-01 Buy

Properties

Melting point :121 °C (dec.) (lit.)
alpha :D25 +39°
Boiling point :408.44°C (rough estimate)
Density :1.4410 (rough estimate)
refractive index :1.6500 (estimate)
storage temp. :-20°C
solubility :Soluble in DMSO (up to 25 mg/ml) or in Water (up to 25 mg/ml)
form :powder
pka :pKa 1.3 (Uncertain)
color :white to light yellow
Water Solubility :soluble
Sensitive :Hygroscopic
Merck :13,8912
BRN :2060675
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 1 month.
InChIKey :ZSJLQEPLLKMAKR-FEQHFJGESA-N
CAS DataBase Reference :18883-66-4
IARC :2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System :Streptozotocin (18883-66-4)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H228 Flammable solid Flammable solids Category 1
Category 2
Danger
Warning
GHS hazard pictograms P210, P240,P241, P280, P370+P378
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H351 Suspected of causing cancer Carcinogenicity Category 2 Warning P201, P202, P281, P308+P313, P405,P501
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and ATP, and formation of superoxide radicals, leading to the destruction of beta cells. The effectiveness of STZ depends on the level of GLUT2 expression, which in turn may be influenced by age, sex, strain, or species.

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