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ChemicalBook >> CAS DataBase List >> TCS 21311

TCS 21311

TCS 21311 price.
  • $32 - $2200
  • Product name: TCS 21311
  • CAS: 1260181-14-3
  • MF: C27H25F3N4O4
  • MW: 526.51
  • EINECS:
  • MDL Number:
  • Synonyms:3-[5-[4-(2-Hydroxy-2-Methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoroMethyl)phenyl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione;TCS 21311;TCS21311; TCS-21311;JAK3/GSK-3β/PKCα Inhibitor - CAS 1260181-14-3 - Calbiochem;3-{5-[4-(2-hydroxy-2-methylpropionyl)piperazin-1-yl]-2-trifluoromethylphenyl}-4-(1H-indol-3-yl)pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-[5-[4-(2-hydroxy-2-methyl-1-oxopropyl)-1-piperazinyl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)-;Protein kinase C,TCS 21311,Glycogen synthase kinase 3,NIBR 3049,TCS21311,GSK-3,Glycogen synthase kinase-3,Inhibitor,JAK,inhibit,NIBR-3049,TCS-21311,Janus kinase,PKC;3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
39 prices
Selected condition:
Brand
  • aablocks
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • CSNpharm
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 50
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • Manufactureraablocks
  • Product numberAA009FMD
  • Product description3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98%
  • Packaging1mg
  • Price$32
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FMD
  • Product description3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98%
  • Packaging5mg
  • Price$105
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FMD
  • Product description3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98%
  • Packaging10mg
  • Price$168
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FMD
  • Product description3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98%
  • Packaging25mg
  • Price$349
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FMD
  • Product description3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98%
  • Packaging50mg
  • Price$552
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009FMD
  • Product description3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98%
  • Packaging100mg
  • Price$745
  • Updated2026-05-28
  • Buy
  • ManufacturerAK Scientific
  • Product number4740DH
  • Product description3-[5-[4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
  • Packaging25mg
  • Price$860
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number4740DH
  • Product description3-[5-[4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)pyrrole-2,5-dione
  • Packaging1mg
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010275
  • Product description3-[5-[4-(2-HYDROXY-2-METHYL-1-OXOPROPYL)-1-PIPERAZINYL]-2-(TRIFLUOROMETHYL)PHENYL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE 95.00%
  • Packaging10MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0010275
  • Product description3-[5-[4-(2-HYDROXY-2-METHYL-1-OXOPROPYL)-1-PIPERAZINYL]-2-(TRIFLUOROMETHYL)PHENYL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE 95.00%
  • Packaging100MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4516
  • Product descriptionTCS 21311
  • Packaging50mg
  • Price$1845
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4516
  • Product descriptionTCS 21311
  • Packaging10mg
  • Price$523
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4516
  • Product descriptionTCS 21311
  • Packaging25mg
  • Price$993
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4516
  • Product descriptionTCS 21311
  • Packaging1mg
  • Price$90
  • Updated2026-05-06
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4516
  • Product descriptionTCS 21311
  • Packaging5mg
  • Price$326
  • Updated2026-05-06
  • Buy
  • ManufacturerBiosynth
  • Product numberFT28015
  • Product descriptionTCS 21311
  • Packaging1mg
  • Price$250
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009FMD 3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98% 1mg $32 2026-05-28 Buy
aablocks AA009FMD 3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98% 5mg $105 2026-05-28 Buy
aablocks AA009FMD 3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98% 10mg $168 2026-05-28 Buy
aablocks AA009FMD 3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98% 25mg $349 2026-05-28 Buy
aablocks AA009FMD 3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98% 50mg $552 2026-05-28 Buy
aablocks AA009FMD 3-(5-(4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl)-2-(trifluoromethyl)phenyl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione 98% 100mg $745 2026-05-28 Buy
AK Scientific 4740DH 3-[5-[4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)pyrrole-2,5-dione 25mg $860 2021-12-16 Buy
AK Scientific 4740DH 3-[5-[4-(2-Hydroxy-2-methylpropanoyl)piperazin-1-yl]-2-(trifluoromethyl)phenyl]-4-(1H-indol-3-yl)pyrrole-2,5-dione 1mg $160 2021-12-16 Buy
American Custom Chemicals Corporation API0010275 3-[5-[4-(2-HYDROXY-2-METHYL-1-OXOPROPYL)-1-PIPERAZINYL]-2-(TRIFLUOROMETHYL)PHENYL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE 95.00% 10MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation API0010275 3-[5-[4-(2-HYDROXY-2-METHYL-1-OXOPROPYL)-1-PIPERAZINYL]-2-(TRIFLUOROMETHYL)PHENYL]-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE 95.00% 100MG $1963.5 2021-12-16 Buy
ApexBio Technology A4516 TCS 21311 50mg $1845 2026-05-06 Buy
ApexBio Technology A4516 TCS 21311 10mg $523 2026-05-06 Buy
ApexBio Technology A4516 TCS 21311 25mg $993 2026-05-06 Buy
ApexBio Technology A4516 TCS 21311 1mg $90 2026-05-06 Buy
ApexBio Technology A4516 TCS 21311 5mg $326 2026-05-06 Buy
Biosynth FT28015 TCS 21311 1mg $250 2026-06-04 Buy

Properties

Boiling point :793.0±60.0 °C(Predicted)
Density :1.436±0.06 g/cm3(Predicted)
storage temp. :+2C to +8C
solubility :<52.65mg/ml in DMSO
form :Yellow solid
pka :7.91±0.60(Predicted)
color :White to yellow
InChIKey :CLGRAWDGLMENOD-UHFFFAOYSA-N
SMILES :O=C1NC(C(C2=CNC3=C2C=CC=C3)=C1C4=CC(N5CCN(C(C(C)(C)O)=O)CC5)=CC=C4C(F)(F)F)=O

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

A potent JAK3 inhibitor; selective for JAK3 over JAK1, JAK2 and TYK2. It also inhibits GSK-3β, PKCα and PKCθ.