TIP60 (human recombinant)
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- $543
- Product name: TIP60 (human recombinant)
- CAS:
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- MW: 0
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- Synonyms:TIP60 (human recombinant)
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Selected condition：
Brand
- Cayman Chemical
Package
- 100μg
- ManufacturerCayman Chemical
- Product number10783
- Product descriptionTIP60 (human, recombinant) ≥50%
- Packaging100μg
- Price$543
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 10783 | TIP60 (human, recombinant) ≥50% | 100μg | $543 | 2026-04-30 | Buy |
Properties
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Description
TIP60 is a member of the MYST family of lysine acetyl transferases. It has been shown to acetylate histones, p53, and the Ataxia Telangiectasia Mutant (ATM) protein kinase.1 As a component of the TIP60-p400 complex, TIP60 acetylates transcription repressors in order to inhibit gene transcription.2 In complexes without p400, TIP60 is part of a chromatin remodeling complex which plays an important role in double-stranded DNA break repair. Acetylation of histone γH2AX allows formation of the γH2AX repair foci, and acetylation of ATM is one of the early steps in double-stranded DNA break repair. Furthermore, TIP60 is bound by the cytoplasmic tail of β-amyloid precursor protein which drives gene transcription, apoptosis, and potentially a role in Alzheimer’s disease pathogenesis.3WARNING This product is not for human or veterinary use.More related product prices