TMP269
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- $41 - $2121
- Product name: TMP269
- CAS: 1314890-29-3
- MF: C25H21F3N4O3S
- MW: 514.52
- EINECS:
- MDL Number:MFCD26522023
- Synonyms:N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide TMP269;TMP269 N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide;BenzaMide, N-[[tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]Methyl]-3-[5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl]-;TMP269;N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)Methyl)-3-(5-(trifluoroMethyl)-1,2,4-oxadiazol-3-yl)benzaMide;N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide;TMP269, >=98%;N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxad
44 prices
Selected condition:
Brand
- aablocks
- Absolute Chiral
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 5mg
- 10mg
- 25mg
- 50mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 200mg
- 10mM*1mLinDMSO
- 100mg
- 250mg
- 10mM(in 1mL DMSO)
- 500mg
- 1G
- 10mM(in1mLDMSO)
- Manufactureraablocks
- Product numberAA009CCC
- Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥95%
- Packaging1mg
- Price$41
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CCC
- Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98%
- Packaging5mg
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CCC
- Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98%
- Packaging10mg
- Price$99
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CCC
- Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+%
- Packaging50mg
- Price$131
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA009CCC
- Product descriptionN-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+%
- Packaging100mg
- Price$157
- Updated2026-05-28
- Buy
- ManufacturerAbsolute Chiral
- Product numberO1152-00-N
- Product descriptionN-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95%
- Packaging25mg
- Price$150
- Updated2026-05-23
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33755
- Product descriptionTMP269 98%
- Packaging25MG
- Price$155
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33755
- Product descriptionTMP269 98%
- Packaging100MG
- Price$500
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33755
- Product descriptionTMP269 98%
- Packaging1G
- Price$1580
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2760AH
- Product descriptionN-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
- Packaging1g
- Price$2121
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number2760AH
- Product descriptionN-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide
- Packaging250mg
- Price$925
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8806
- Product descriptionTMP269
- Packaging10mM(in 1mL DMSO)
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8806
- Product descriptionTMP269
- Packaging10mg
- Price$198
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8806
- Product descriptionTMP269
- Packaging10mM(in1mLDMSO)
- Price$132
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA8806
- Product descriptionTMP269
- Packaging5mg
- Price$121
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberHY-18360
- Product descriptionTMP269 98.16%
- Packaging5mg
- Price$105
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA009CCC | N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥95% | 1mg | $41 | 2026-05-28 | Buy |
| aablocks | AA009CCC | N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98% | 5mg | $55 | 2026-05-28 | Buy |
| aablocks | AA009CCC | N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide ≥98% | 10mg | $99 | 2026-05-28 | Buy |
| aablocks | AA009CCC | N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+% | 50mg | $131 | 2026-05-28 | Buy |
| aablocks | AA009CCC | N-[[Tetrahydro-4-(4-phenyl-2-thiazolyl)-2H-pyran-4-yl]methyl]-3-[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]benzamide 98+% | 100mg | $157 | 2026-05-28 | Buy |
| Absolute Chiral | O1152-00-N | N-((4-(4-phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide 95% | 25mg | $150 | 2026-05-23 | Buy |
| ACHEMBLOCK | O33755 | TMP269 98% | 25MG | $155 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33755 | TMP269 98% | 100MG | $500 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33755 | TMP269 98% | 1G | $1580 | 2026-05-27 | Buy |
| AK Scientific | 2760AH | N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide | 1g | $2121 | 2021-12-16 | Buy |
| AK Scientific | 2760AH | N-((4-(4-Phenylthiazol-2-yl)tetrahydro-2H-pyran-4-yl)methyl)-3-(5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl)benzamide | 250mg | $925 | 2021-12-16 | Buy |
| ApexBio Technology | A8806 | TMP269 | 10mM(in 1mL DMSO) | $180 | 2021-12-16 | Buy |
| ApexBio Technology | A8806 | TMP269 | 10mg | $198 | 2026-05-06 | Buy |
| ApexBio Technology | A8806 | TMP269 | 10mM(in1mLDMSO) | $132 | 2026-05-06 | Buy |
| ApexBio Technology | A8806 | TMP269 | 5mg | $121 | 2026-05-06 | Buy |
| Arctom | HY-18360 | TMP269 98.16% | 5mg | $105 | 2026-05-26 | Buy |
Properties
Density :1.347±0.06 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :≥23 mg/mL in DMSO; insoluble in H2O; ≥21 mg/mL in EtOH with ultrasonic
form :solid
pka :13.66±0.46(Predicted)
color :White to off-white
SMILES :FC(F)(C1=NC(C2=CC(C(NCC3(C4=NC(C5=CC=CC=C5)=CS4)CCOCC3)=O)=CC=C2)=NO1)F
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :≥23 mg/mL in DMSO; insoluble in H2O; ≥21 mg/mL in EtOH with ultrasonic
form :solid
pka :13.66±0.46(Predicted)
color :White to off-white
SMILES :FC(F)(C1=NC(C2=CC(C(NCC3(C4=NC(C5=CC=CC=C5)=CS4)CCOCC3)=O)=CC=C2)=NO1)F
Safety Information
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Description
While class I HDACs are localized predominantly within the nucleus, class II HDACs shuttle into and out of the nucleus in response to intracellular signaling. Class IIa HDACs, which include HDAC4, 5, 7, and 9, commonly act as corepressors and play diverse roles in cell biology. TMP269 is a cell-permeable inhibitor of class IIa HDACs (IC50s = 126, 80, 36, and 19 nM for HDAC4, 5, 7, and 9, respectively). It contains a metal-binding group, trifluoromethyloxadiazole that confers selectivity for class IIa HDACs.Related product price
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Suppliers and manufacturers
Shanghai Boyle Chemical Co., Ltd.
Dalian Meilun Biotech Co., Ltd.
Haoyuan Chemexpress Co., Ltd.
MedChemexpress LLC
Guangzhou Isun Pharmaceutical Co., Ltd
Bide Pharmatech Ltd.
AdooQ Bioscience CHINA
Shanghai JiYi Biotechnology Co. Ltd.
LETOPHARM LIMITED
Shanghai Lollane Biological Technology Co.,Ltd.




