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ChemicalBook >> CAS DataBase List >> TW-37

TW-37

TW-37 price.
  • $32 - $17600
  • Product name: TW-37
  • CAS: 877877-35-5
  • MF: C33H35NO6S
  • MW: 573.7
  • EINECS:-0
  • MDL Number:MFCD17010275
  • Synonyms:TW-37;N-[4-[(2-tert-Butylphenyl)sulfonyl]phenyl]-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide;N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide;N-[4-[[2-(1,1-Dimethylethyl)phenyl]sulfonyl]phenyl]-2,3,4-trihydroxy-5-[[2-(1-methylethyl)phenyl]methyl]benzamide;5-(2-isopropylbenzyl)-N-(4-(2-tert-butylphenylsulfonyl)phenyl)-2,3,4-trihydroxybenzamide;N-[4-[(2-tert-Butylphenyl)sulfonyl]phenyl]-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide TW-37;Bcl-2 Inhibitor N-[4-[(2-tert-Butylphenyl)sulfonyl]phenyl]-2,3,4-trihydroxy-5-[(2-isopropylphenyl)methyl]benzamide;CS-299
Price26 Properties Safety Information Description
26 prices
Selected condition：
Brand
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 50
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 1G
  • ManufacturerAmbeed
  • Product numberA252493
  • Product descriptionN-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+%
  • Packaging1mg
  • Price$32
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252493
  • Product descriptionN-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+%
  • Packaging5mg
  • Price$54
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252493
  • Product descriptionN-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+%
  • Packaging10mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252493
  • Product descriptionN-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+%
  • Packaging50mg
  • Price$333
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252493
  • Product descriptionN-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+%
  • Packaging100mg
  • Price$583
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA252493
  • Product descriptionN-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+%
  • Packaging250mg
  • Price$1166
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000892
  • Product descriptionTW-37 95.00%
  • Packaging10MG
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000892
  • Product descriptionTW-37 95.00%
  • Packaging50MG
  • Price$1260
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000892
  • Product descriptionTW-37 95.00%
  • Packaging1G
  • Price$17600
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4234
  • Product descriptionTW-37
  • Packaging50mg
  • Price$470
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180746
  • Product descriptiontw-37 >98%
  • Packaging100mg
  • Price$765
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180746
  • Product descriptiontw-37 >98%
  • Packaging250mg
  • Price$1356.6
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb180746
  • Product descriptiontw-37 >98%
  • Packaging1g
  • Price$2691.1
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number20999
  • Product descriptionTW-37 ≥98%
  • Packaging5mg
  • Price$110
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20999
  • Product descriptionTW-37 ≥98%
  • Packaging10mg
  • Price$185
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20999
  • Product descriptionTW-37 ≥98%
  • Packaging25mg
  • Price$380
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A252493 N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+% 1mg $32 2021-12-16 Buy
Ambeed A252493 N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+% 5mg $54 2021-12-16 Buy
Ambeed A252493 N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+% 10mg $90 2021-12-16 Buy
Ambeed A252493 N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+% 50mg $333 2021-12-16 Buy
Ambeed A252493 N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+% 100mg $583 2021-12-16 Buy
Ambeed A252493 N-[4-(2-tert-Butylphenylsulfonyl)phenyl]-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide 98+% 250mg $1166 2021-12-16 Buy
American Custom Chemicals Corporation INB0000892 TW-37 95.00% 10MG $600 2021-12-16 Buy
American Custom Chemicals Corporation INB0000892 TW-37 95.00% 50MG $1260 2021-12-16 Buy
American Custom Chemicals Corporation INB0000892 TW-37 95.00% 1G $17600 2021-12-16 Buy
ApexBio Technology A4234 TW-37 50mg $470 2021-12-16 Buy
Biorbyt Ltd orb180746 tw-37 >98% 100mg $765 2021-12-16 Buy
Biorbyt Ltd orb180746 tw-37 >98% 250mg $1356.6 2021-12-16 Buy
Biorbyt Ltd orb180746 tw-37 >98% 1g $2691.1 2021-12-16 Buy
Cayman Chemical 20999 TW-37 ≥98% 5mg $110 2024-03-01 Buy
Cayman Chemical 20999 TW-37 ≥98% 10mg $185 2024-03-01 Buy
Cayman Chemical 20999 TW-37 ≥98% 25mg $380 2024-03-01 Buy
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Properties

Boiling point :723.7±60.0 °C(Predicted)
Density :1.280
storage temp. :Store at -20°C
solubility :insoluble in H2O; ≥19.75 mg/mL in DMSO; ≥3.41 mg/mL in EtOH with gentle warming and ultrasonic
form :A crystalline solid
pka :7.86±0.50(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330 Rinse mouth.
P501 Dispose of contents/container to..…

Description

TW-37 is an inhibitor of the Bcl-2 family proteins Bcl-2, Mcl-1, and Bcl-xL (Kis = 120, 260, and 1,100 nM, respectively). It induces apoptosis, inhibits migration and capillary sprouting, and blocks the expression of the angiogenic chemokines CXCL1 and CXCL8 in endothelial cells. TW-37 decreases the density of functional human microvessels in the severe combined immunodeficient mouse model of human angiogenesis when administered intravenously. It has apoptotic action against leukemia, lymphoma, and pancreatic cancer cells.

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Suppliers and manufacturers

career henan chemical co
TW-37
$0.01 /1KG
TW-37 CAS:877877-35-5
Accela ChemBio Inc.
Dideu Industries Group Limited
Finetech Industry Limited
Hefei Hirisun Pharmatech Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited
InvivoChem
TargetMol Chemicals Inc.
Hu Bei Jiutian Bio-medical Technology CO.,Ltd
LEAPCHEM CO., LTD.