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ChemicalBook >> CAS DataBase List >> Tadalafil-d3

Tadalafil-d3

Tadalafil-d3 price.
  • $178 - $1963.5
  • Product name: Tadalafil-d3
  • CAS: 960226-55-5
  • MF: C22H18N3O4
  • MW: 388.39602
  • EINECS:
  • MDL Number:MFCD04116200
  • Synonyms:Tadalafil-d3;Pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-(methyl-d3)-, (6R,12aR)-;PubChem ID: 46782966;[2H3]-Tadalafil;Tadalafil D3Q: What is Tadalafil D3 Q: What is the CAS Number of Tadalafil D3 Q: What is the storage condition of Tadalafil D3 Q: What are the applications of Tadalafil D3
Price5 Properties Safety Information Description
5 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • TRC
Package
  • 1MG
  • 5mg
  • 10MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0005317
  • Product descriptionTADALAFIL-D3 95.00%
  • Packaging1MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberRDL0005317
  • Product descriptionTADALAFIL-D3 95.00%
  • Packaging10MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number25030
  • Product descriptionTadalafil-d3 ≥99% deuterated forms (d1-d3)
  • Packaging1mg
  • Price$178
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number25030
  • Product descriptionTadalafil-d3 ≥99% deuterated forms (d1-d3)
  • Packaging5mg
  • Price$704
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberT004510
  • Product descriptionTadalafil-d3
  • Packaging10mg
  • Price$1390
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation RDL0005317 TADALAFIL-D3 95.00% 1MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation RDL0005317 TADALAFIL-D3 95.00% 10MG $1963.5 2021-12-16 Buy
Cayman Chemical 25030 Tadalafil-d3 ≥99% deuterated forms (d1-d3) 1mg $178 2024-03-01 Buy
Cayman Chemical 25030 Tadalafil-d3 ≥99% deuterated forms (d1-d3) 5mg $704 2024-03-01 Buy
TRC T004510 Tadalafil-d3 10mg $1390 2021-12-16 Buy

Properties

Melting point :281-283°C
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly)
form :Solid
color :White to Off-White
Stability :Unstable in Methanol
InChI :InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21+/s3
InChIKey :WOXKDUGGOYFFRN-PDIFIXMTNA-N
SMILES :c12c3ccccc3nc1[C@H](c1cc3OCOc3cc1)N1C(=O)CN(C)C(=O)[C@H]1C2 |&1:9,27,r|

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tadalafil-d3 is intended for use as an internal standard for the quantification of tadalafil by GC- or LC-MS. Tadalafil is a potent inhibitor of phosphodiesterase 5 (PDE5; IC50 = 1.2 nM). It is selective for PDE5 over PDE1-4 and 7-10 (IC50s = 9.2-280 μM), however, it does also inhibit PDE11 (IC50 = 11 nM). In vivo, tadalafil (10 mg/kg) decreases production of the proinflammatory cytokines TNF-α, IL-1β, and IL-6 and improves renal function in a rat model of ischemia/reperfusion injury. It also reduces development of tobacco smoke-induced emphysema and pulmonary hypertension in mice. Formulations containing tadalafil have been used to treat erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.

More related product prices

Tadalafil KetolactaM (6R,trans)-6-(3,4-dihydroxyphenyl)-2,3,6,7,12,12a-hexahydro-2-Methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione cis-Tadalafil cis-ent-Tadalafil ent-Tadalafil

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Suppliers and manufacturers

SIMSON PHARMA LIMITED
Tadalafil-D3
$282.00 /10mg
Tadalafil-D3 CAS:960226-55-5
BOC Sciences
Hubei Jusheng Technology Co.,Ltd. BOC Sciences J & K SCIENTIFIC LTD. Chemsky（shanghai）International Co.,Ltd. Daicel Chiral Technologies (China)CO.,LTD Cato Research Chemicals Inc. ChemStrong Scientific Co.,Ltd Clearsynth Canada Inc.