Terameprocol
|
- $16 - $1950
- Product name: Terameprocol
- CAS: 24150-24-1
- MF: C22H30O4
- MW: 358.47
- EINECS:
- MDL Number:MFCD11113155
- Synonyms:EM-1421;M4N;TETRAMEPROCOL;TETRAMETHYL NDGA;TETRAMETHYL NORDIHYDROGUAIARETIC ACID;TMNDGA;Butane, 1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethyl-, meso-;Meso-tetramethoxy-4,4'-(2,3-dimethyltetramethylene)dipyrocatechol
35 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- 250MG
- 500mg
- 1G
- Manufactureraablocks
- Product numberAA00BE83
- Product descriptiontetramethyl Nordihydroguaiaretic Acid
- Packaging10mg
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE83
- Product descriptiontetramethyl Nordihydroguaiaretic Acid
- Packaging25mg
- Price$86
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE83
- Product descriptiontetramethyl Nordihydroguaiaretic Acid
- Packaging50mg
- Price$126
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00BE83
- Product descriptiontetramethyl Nordihydroguaiaretic Acid ≥95%
- Packaging100mg
- Price$225
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227178
- Product descriptionTerameprocol 97.00%
- Packaging100MG
- Price$375
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227178
- Product descriptionTerameprocol 97.00%
- Packaging250MG
- Price$750
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227178
- Product descriptionTerameprocol 97.00%
- Packaging1G
- Price$1950
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number2065AH
- Product descriptionTerameprocol
- Packaging50mg
- Price$114
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005333
- Product descriptionTERAMEPROCOL 95.00%
- Packaging50MG
- Price$118.65
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005333
- Product descriptionTERAMEPROCOL 95.00%
- Packaging100MG
- Price$568.79
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005333
- Product descriptionTERAMEPROCOL 95.00%
- Packaging1G
- Price$776.16
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4630
- Product descriptiontetramethyl Nordihydroguaiaretic Acid
- Packaging1g
- Price$286
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberC4630
- Product descriptiontetramethylNordihydroguaiareticAcid
- Packaging1g
- Price$214
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC4630
- Product descriptiontetramethyl Nordihydroguaiaretic Acid
- Packaging500mg
- Price$164
- Updated2026-05-06
- Buy
- ManufacturerCayman Chemical
- Product number70302
- Product descriptiontetramethyl Nordihydroguaiaretic Acid ≥95%
- Packaging50mg
- Price$131
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number70302
- Product descriptiontetramethyl Nordihydroguaiaretic Acid ≥95%
- Packaging100mg
- Price$225
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00BE83 | tetramethyl Nordihydroguaiaretic Acid | 10mg | $56 | 2026-05-28 | Buy |
| aablocks | AA00BE83 | tetramethyl Nordihydroguaiaretic Acid | 25mg | $86 | 2026-05-28 | Buy |
| aablocks | AA00BE83 | tetramethyl Nordihydroguaiaretic Acid | 50mg | $126 | 2026-05-28 | Buy |
| aablocks | AA00BE83 | tetramethyl Nordihydroguaiaretic Acid ≥95% | 100mg | $225 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227178 | Terameprocol 97.00% | 100MG | $375 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227178 | Terameprocol 97.00% | 250MG | $750 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227178 | Terameprocol 97.00% | 1G | $1950 | 2026-05-27 | Buy |
| AK Scientific | 2065AH | Terameprocol | 50mg | $114 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005333 | TERAMEPROCOL 95.00% | 50MG | $118.65 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005333 | TERAMEPROCOL 95.00% | 100MG | $568.79 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005333 | TERAMEPROCOL 95.00% | 1G | $776.16 | 2021-12-16 | Buy |
| ApexBio Technology | C4630 | tetramethyl Nordihydroguaiaretic Acid | 1g | $286 | 2026-05-06 | Buy |
| ApexBio Technology | C4630 | tetramethylNordihydroguaiareticAcid | 1g | $214 | 2021-12-16 | Buy |
| ApexBio Technology | C4630 | tetramethyl Nordihydroguaiaretic Acid | 500mg | $164 | 2026-05-06 | Buy |
| Cayman Chemical | 70302 | tetramethyl Nordihydroguaiaretic Acid ≥95% | 50mg | $131 | 2026-04-30 | Buy |
| Cayman Chemical | 70302 | tetramethyl Nordihydroguaiaretic Acid ≥95% | 100mg | $225 | 2026-04-30 | Buy |
Properties
Melting point :101-102 °C
Boiling point :458.5±40.0 °C(Predicted)
Density :1.036±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to off-white
InChI :1S/C22H30O4/c1-15(11-17-7-9-19(23-3)21(13-17)25-5)16(2)12-18-8-10-20(24-4)22(14-18)26-6/h7-10,13-16H,11-12H2,1-6H3/t15-,16+
InChIKey :ORQFDHFZSMXRLM-IYBDPMFKSA-N
SMILES :COc1ccc(C[C@H](C)[C@H](C)Cc2ccc(OC)c(OC)c2)cc1OC
Boiling point :458.5±40.0 °C(Predicted)
Density :1.036±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: ≥10mg/mL
form :powder
color :white to off-white
InChI :1S/C22H30O4/c1-15(11-17-7-9-19(23-3)21(13-17)25-5)16(2)12-18-8-10-20(24-4)22(14-18)26-6/h7-10,13-16H,11-12H2,1-6H3/t15-,16+
InChIKey :ORQFDHFZSMXRLM-IYBDPMFKSA-N
SMILES :COc1ccc(C[C@H](C)[C@H](C)Cc2ccc(OC)c(OC)c2)cc1OC
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
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| Precautionary statements: |
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Description
tetramethyl Nordihydroguaiaretic acid (TMNDGA) is a synthetic derivative of NDGA, a non-selective lipoxygenase inhibitor. It inhibits Sp1 transcription factor binding at the HIV long terminal repeat promoter and at the α-ICP4 promoter, a gene essential for HSV replication, with IC50 values of 11 and 43.5 μM respectively TMNDGA induces growth arrest and apoptosis by suppressing Sp1-dependent Cdc2 and survivin gene expression giving rise to its antitumorigenic activity. The in vivo growth of xenografts in numerous human tumor types was suppressed upon treatment with TMNDGA. It also inhibits the growth of mouse and human melanomas and human colon cancer in vivo without causing other tissue toxicity. TMNDGA is currently in Phase I & II clinical trials for treatment of high grade glioma brain tumors.Related product price
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