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ChemicalBook >> CAS DataBase List >> Torcetrapib

Torcetrapib

Torcetrapib price.
  • $38 - $8316
  • Product name: Torcetrapib
  • CAS: 262352-17-0
  • MF: C26H25F9N2O4
  • MW: 600.47
  • EINECS:
  • MDL Number:MFCD09260777
  • Synonyms:CP 529414;(2R)-ethyl 4-((3,5-bis(trifluoroMethyl)benzyl)(Methoxycarbonyl)aMino)-2-ethyl-6-(trifluoroMethyl)-3,4-dihydroquinoline-1(2H)-carboxylate;Torcetrapib (CP-529414);cp529;(2R,4S)-ethyl 2-ethyl-4-(methoxycarbonyl)-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate;Torcetropib;TORCETRAPIB-D3;(2R,4S)-4-[(3,5-Bis-trifluoromethylbenzyl)methoxycarbonylamino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester
65 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 250mg
  • 1000mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10
  • 50
  • 1g
  • 1.00g
  • 10mM(in 1mL DMSO)
  • 1mg
  • 2mg
  • 5mg
  • 10mg
  • 25mg
  • 100MG
  • 10mM(in1mLDMSO)
  • 50mg
  • Manufactureraablocks
  • Product numberAA002SB2
  • Product descriptionTorcetrapib
  • Packaging2mg
  • Price$44
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002SB2
  • Product descriptionTorcetrapib
  • Packaging5mg
  • Price$55
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002SB2
  • Product descriptionTorcetrapib
  • Packaging10mg
  • Price$68
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002SB2
  • Product descriptionTorcetrapib
  • Packaging25mg
  • Price$119
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA002SB2
  • Product descriptionTorcetrapib
  • Packaging50mg
  • Price$204
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227529
  • Product descriptionTorcetrapib 97.00%
  • Packaging100MG
  • Price$435
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberY227529
  • Product descriptionTorcetrapib 97.00%
  • Packaging25MG
  • Price$145
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib 98%(HPLC)
  • Packaging10mg
  • Price$129
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib 98%(HPLC)
  • Packaging1mg
  • Price$47
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib
  • Packaging5mg
  • Price$89
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib 98%(HPLC)
  • Packaging5mg
  • Price$93
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib 98%(HPLC)
  • Packaging25mg
  • Price$258
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib 98%(HPLC)
  • Packaging50mg
  • Price$412
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib 98%(HPLC)
  • Packaging100mg
  • Price$661
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0216
  • Product descriptionTorcetrapib
  • Packaging100mg
  • Price$995
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4378
  • Product descriptionTorcetrapib
  • Packaging50mg
  • Price$369
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA002SB2 Torcetrapib 2mg $44 2026-05-28 Buy
aablocks AA002SB2 Torcetrapib 5mg $55 2026-05-28 Buy
aablocks AA002SB2 Torcetrapib 10mg $68 2026-05-28 Buy
aablocks AA002SB2 Torcetrapib 25mg $119 2026-05-28 Buy
aablocks AA002SB2 Torcetrapib 50mg $204 2026-05-28 Buy
ACHEMBLOCK Y227529 Torcetrapib 97.00% 100MG $435 2026-05-27 Buy
ACHEMBLOCK Y227529 Torcetrapib 97.00% 25MG $145 2026-05-27 Buy
AK Scientific Y0216 Torcetrapib 98%(HPLC) 10mg $129 2026-06-04 Buy
AK Scientific Y0216 Torcetrapib 98%(HPLC) 1mg $47 2026-06-04 Buy
AK Scientific Y0216 Torcetrapib 5mg $89 2021-12-16 Buy
AK Scientific Y0216 Torcetrapib 98%(HPLC) 5mg $93 2026-06-04 Buy
AK Scientific Y0216 Torcetrapib 98%(HPLC) 25mg $258 2026-06-04 Buy
AK Scientific Y0216 Torcetrapib 98%(HPLC) 50mg $412 2026-06-04 Buy
AK Scientific Y0216 Torcetrapib 98%(HPLC) 100mg $661 2026-06-04 Buy
AK Scientific Y0216 Torcetrapib 100mg $995 2021-12-16 Buy
ApexBio Technology A4378 Torcetrapib 50mg $369 2026-05-06 Buy

Properties

Melting point :54-58°C
Boiling point :504.8±50.0 °C(Predicted)
Density :1.42
storage temp. :Store at RT
solubility :DMSO: >5mg/mL
pka :-1.87±0.40(Predicted)
form :powder
color :white
optical activity :[α]/D >-70°
InChIKey :CMSGWTNRGKRWGS-NQIIRXRSSA-N
SMILES :N1(C(OCC)=O)C2=C(C=C(C(F)(F)F)C=C2)[C@@H](N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C(OC)=O)C[C@H]1CC
CAS DataBase Reference :262352-17-0(CAS DataBase Reference)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

Cholesteryl ester transfer protein (CETP) catalyzes the exchange of cholesteryl esters from high-density lipoprotein (HDL) cholesterol to apolipoprotein B-containing lipoproteins, including very low-density lipoprotein (VLDL) and LDL. Torcetrapib is an inhibitor of CETP activity (IC50 = 50 nM) that raises HDL cholesterol and reduces LDL cholesterol levels by forming a nonproductive complex between CETP and HDL. Although torcetrapib produced consistent antiatherogenic effects in rabbits, clinical trials of torcetrapib were terminated early due to deleterious hypertensive effects. PDGFR, HGFR (c-Met), IL-2 receptor, and ErbB1- tyrosine kinase have subsequently been identified as direct off-targets of this compound.

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