Torcetrapib
|
- $38 - $8316
- Product name: Torcetrapib
- CAS: 262352-17-0
- MF: C26H25F9N2O4
- MW: 600.47
- EINECS:
- MDL Number:MFCD09260777
- Synonyms:CP 529414;(2R)-ethyl 4-((3,5-bis(trifluoroMethyl)benzyl)(Methoxycarbonyl)aMino)-2-ethyl-6-(trifluoroMethyl)-3,4-dihydroquinoline-1(2H)-carboxylate;Torcetrapib (CP-529414);cp529;(2R,4S)-ethyl 2-ethyl-4-(methoxycarbonyl)-6-(trifluoromethyl)-3,4-dihydroquinoline-1(2H)-carboxylate;Torcetropib;TORCETRAPIB-D3;(2R,4S)-4-[(3,5-Bis-trifluoromethylbenzyl)methoxycarbonylamino]-2-ethyl-6-trifluoromethyl-3,4-dihydro-2H-quinoline-1-carboxylic acid ethyl ester
65 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 250mg
- 1000mg
- 10mM*1mLinDMSO(Solution)
- 10mM*1mLinDMSO(Solid+Solvent)
- 10
- 50
- 1g
- 1.00g
- 10mM(in 1mL DMSO)
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 100MG
- 10mM(in1mLDMSO)
- 50mg
- Manufactureraablocks
- Product numberAA002SB2
- Product descriptionTorcetrapib
- Packaging2mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002SB2
- Product descriptionTorcetrapib
- Packaging5mg
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002SB2
- Product descriptionTorcetrapib
- Packaging10mg
- Price$68
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002SB2
- Product descriptionTorcetrapib
- Packaging25mg
- Price$119
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA002SB2
- Product descriptionTorcetrapib
- Packaging50mg
- Price$204
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227529
- Product descriptionTorcetrapib 97.00%
- Packaging100MG
- Price$435
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberY227529
- Product descriptionTorcetrapib 97.00%
- Packaging25MG
- Price$145
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib 98%(HPLC)
- Packaging10mg
- Price$129
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib 98%(HPLC)
- Packaging1mg
- Price$47
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib
- Packaging5mg
- Price$89
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib 98%(HPLC)
- Packaging5mg
- Price$93
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib 98%(HPLC)
- Packaging25mg
- Price$258
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib 98%(HPLC)
- Packaging50mg
- Price$412
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib 98%(HPLC)
- Packaging100mg
- Price$661
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberY0216
- Product descriptionTorcetrapib
- Packaging100mg
- Price$995
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4378
- Product descriptionTorcetrapib
- Packaging50mg
- Price$369
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA002SB2 | Torcetrapib | 2mg | $44 | 2026-05-28 | Buy |
| aablocks | AA002SB2 | Torcetrapib | 5mg | $55 | 2026-05-28 | Buy |
| aablocks | AA002SB2 | Torcetrapib | 10mg | $68 | 2026-05-28 | Buy |
| aablocks | AA002SB2 | Torcetrapib | 25mg | $119 | 2026-05-28 | Buy |
| aablocks | AA002SB2 | Torcetrapib | 50mg | $204 | 2026-05-28 | Buy |
| ACHEMBLOCK | Y227529 | Torcetrapib 97.00% | 100MG | $435 | 2026-05-27 | Buy |
| ACHEMBLOCK | Y227529 | Torcetrapib 97.00% | 25MG | $145 | 2026-05-27 | Buy |
| AK Scientific | Y0216 | Torcetrapib 98%(HPLC) | 10mg | $129 | 2026-06-04 | Buy |
| AK Scientific | Y0216 | Torcetrapib 98%(HPLC) | 1mg | $47 | 2026-06-04 | Buy |
| AK Scientific | Y0216 | Torcetrapib | 5mg | $89 | 2021-12-16 | Buy |
| AK Scientific | Y0216 | Torcetrapib 98%(HPLC) | 5mg | $93 | 2026-06-04 | Buy |
| AK Scientific | Y0216 | Torcetrapib 98%(HPLC) | 25mg | $258 | 2026-06-04 | Buy |
| AK Scientific | Y0216 | Torcetrapib 98%(HPLC) | 50mg | $412 | 2026-06-04 | Buy |
| AK Scientific | Y0216 | Torcetrapib 98%(HPLC) | 100mg | $661 | 2026-06-04 | Buy |
| AK Scientific | Y0216 | Torcetrapib | 100mg | $995 | 2021-12-16 | Buy |
| ApexBio Technology | A4378 | Torcetrapib | 50mg | $369 | 2026-05-06 | Buy |
Properties
Melting point :54-58°C
Boiling point :504.8±50.0 °C(Predicted)
Density :1.42
storage temp. :Store at RT
solubility :DMSO: >5mg/mL
pka :-1.87±0.40(Predicted)
form :powder
color :white
optical activity :[α]/D >-70°
InChIKey :CMSGWTNRGKRWGS-NQIIRXRSSA-N
SMILES :N1(C(OCC)=O)C2=C(C=C(C(F)(F)F)C=C2)[C@@H](N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C(OC)=O)C[C@H]1CC
CAS DataBase Reference :262352-17-0(CAS DataBase Reference)
Boiling point :504.8±50.0 °C(Predicted)
Density :1.42
storage temp. :Store at RT
solubility :DMSO: >5mg/mL
pka :-1.87±0.40(Predicted)
form :powder
color :white
optical activity :[α]/D >-70°
InChIKey :CMSGWTNRGKRWGS-NQIIRXRSSA-N
SMILES :N1(C(OCC)=O)C2=C(C=C(C(F)(F)F)C=C2)[C@@H](N(CC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C(OC)=O)C[C@H]1CC
CAS DataBase Reference :262352-17-0(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||
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Description
Cholesteryl ester transfer protein (CETP) catalyzes the exchange of cholesteryl esters from high-density lipoprotein (HDL) cholesterol to apolipoprotein B-containing lipoproteins, including very low-density lipoprotein (VLDL) and LDL. Torcetrapib is an inhibitor of CETP activity (IC50 = 50 nM) that raises HDL cholesterol and reduces LDL cholesterol levels by forming a nonproductive complex between CETP and HDL. Although torcetrapib produced consistent antiatherogenic effects in rabbits, clinical trials of torcetrapib were terminated early due to deleterious hypertensive effects. PDGFR, HGFR (c-Met), IL-2 receptor, and ErbB1- tyrosine kinase have subsequently been identified as direct off-targets of this compound.Related product price
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