Torin 1
|
- $28 - $4500
- Product name: Torin 1
- CAS: 1222998-36-8
- MF: C35H28F3N5O2
- MW: 607.62
- EINECS:
- MDL Number:MFCD18782653
- Synonyms:1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one;1-[4-(4-PROPANOYLPIPERAZIN-1-YL)-3-(TRIFLUOROMETHYL)PHENYL]-9-QUINOLIN-3-YLBENZO[H][1,6]NAPHTHYRIDIN-2-ONE;Torin 1;Benzo[h]-1,6-naphthyridin-2(1H)-one, 1-[4-[4-(1-oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)-;1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one Torin 1;Torin 1 1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one;1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one;Torin 1, >=98%
51 prices
Selected condition：
Brand
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 1unit
- 5MG
- 10mg
- 10.00mg
- 25.00mg
- 25MG
- 50.00mg
- 50mg
- 10
- 100MG
- 200mg
- 250mg
- 500mg
- 1G
- 10mM*1mLinDMSO
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging25MG
- Price$215
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging100MG
- Price$650
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging1G
- Price$2150
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product number10730
- Product descriptionTorin 1 98%
- Packaging5MG
- Price$75
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0294
- Product descriptionTorin1
- Packaging50mg
- Price$640
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberY0294
- Product descriptionTorin1
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging25mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging5mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8312
- Product descriptionTorin1
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging10mg
- Price$120
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging5mg
- Price$80
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging25mg
- Price$240
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberCFN60098
- Product descriptionTorin1 ≥98%
- Packaging10mg
- Price$218
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging100mg
- Price$570
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-13003
- Product descriptionTorin1 99.28%
- Packaging50mg
- Price$380
- Updated2026-05-26
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1833
- Product descriptionTorin 1
- Packaging5mg
- Price$99
- Updated2026-05-19
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | 10730 | Torin 1 98% | 25MG | $215 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 100MG | $650 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 1G | $2150 | 2026-05-27 | Buy |
| ACHEMBLOCK | 10730 | Torin 1 98% | 5MG | $75 | 2026-05-27 | Buy |
| AK Scientific | Y0294 | Torin1 | 50mg | $640 | 2021-12-16 | Buy |
| AK Scientific | Y0294 | Torin1 | 10mg | $218 | 2021-12-16 | Buy |
| ApexBio Technology | A8312 | Torin1 | 25mg | $270 | 2021-12-16 | Buy |
| ApexBio Technology | A8312 | Torin1 | 5mg | $70 | 2021-12-16 | Buy |
| ApexBio Technology | A8312 | Torin1 | 1unit | $28 | 2021-12-16 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 10mg | $120 | 2026-05-26 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 5mg | $80 | 2026-05-26 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 25mg | $240 | 2026-05-26 | Buy |
| Arctom | CFN60098 | Torin1 ≥98% | 10mg | $218 | 2021-12-16 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 100mg | $570 | 2026-05-26 | Buy |
| Arctom | HY-13003 | Torin1 99.28% | 50mg | $380 | 2026-05-26 | Buy |
| Axon Medchem | Axon1833 | Torin 1 | 5mg | $99 | 2026-05-19 | Buy |
Properties
Melting point :>223°C (dec.)
Boiling point :817.2±65.0 °C(Predicted)
Density :1.362
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 8 mg/ml).
form :Yellowish-white powder
pka :4.19±0.20(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :AKCRNFFTGXBONI-UHFFFAOYSA-N
SMILES :N1(C2=CC=C(N3CCN(C(=O)CC)CC3)C(C(F)(F)F)=C2)C2=C(C=NC3=CC=C(C4=CC5C(N=C4)=CC=CC=5)C=C32)C=CC1=O
Boiling point :817.2±65.0 °C(Predicted)
Density :1.362
storage temp. :+2C to +8C
solubility :Soluble in DMSO (up to 8 mg/ml).
form :Yellowish-white powder
pka :4.19±0.20(Predicted)
color :White or off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
InChIKey :AKCRNFFTGXBONI-UHFFFAOYSA-N
SMILES :N1(C2=CC=C(N3CCN(C(=O)CC)CC3)C(C(F)(F)F)=C2)C2=C(C=NC3=CC=C(C4=CC5C(N=C4)=CC=CC=5)C=C32)C=CC1=O
Safety Information
| Symbol(GHS): |
|
|||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||||||||||||||||
| Precautionary statements: |
|
Description
Torin 1 is a potent and selective inhibitor of mTOR (IC50 = 2 and 10 nM for mTORC1 and mTORC2, respectively). It shows over 100-fold selectivity for mTOR over PI3Kα and other PI3K-like kinases, including ATM, DNA-PK, and hVps34, as well as 450 other protein kinases. Torin 1, is efficacious at a dose of 20 mg/kg in inhibiting downstream effectors of mTOR in mice.Related product price
-
Rapamycin
$9-6160 -
Pictilisib (GDC-0941)
$16-3563.2 -
KU-0063794
$23-2839
Suppliers and manufacturers
CONIER CHEM AND PHARMA LIMITED
Dideu Industries Group Limited
Zhejiang J&C Biological Technology Co.,Limited
HANGZHOU LEAP CHEM CO., LTD.
Zibo Hangyu Biotechnology Development Co., Ltd
Aladdin Scientific
NANJING YINGWEN BIOTECHNOLOGY CO LTD
Amadis Chemical Company Limited
Hunan Huayi Zhide Pharmaceutical Technology Co., Ltd.
![1-[4-[4-(1-Oxopropyl)-1-piperazinyl]-3-(trifluoromethyl)phenyl]-9-(3-quinolinyl)benzo[h]-1,6-naphthyridin-2(1H)-one](https://img.chemicalbook.com/ProductImageEN/2018-12/small/a8d9b725-3501-41e9-8ab0-ffa7fdbdccca.jpg){kind=small}