CUDC-101
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- $28 - $2691.1
- Product name: CUDC-101
- CAS: 1012054-59-9
- MF: C24H26N4O4
- MW: 434.49
- EINECS:-0
- MDL Number:MFCD15528940
- Synonyms:CUDC101;CUDC-101;7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide;HeptanaMide, 7-[[4-[(3-ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxy-;7-[[4-[(3-Ethynylphenyl)aMino]-7-Methoxy-6-quinazolinyl]oxy]-N-hydroxyheptanaMide;7-[[4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yl]oxy]-N-hydroxyheptanamide CUDC-101;7-[4-(3-ethynylanilino)-7-methoxyquinazolin-6-yl]oxy-N-hydroxyheptanamide;CUDC-101, >=98%
44 prices
Selected condition：
Brand
- Activate Scientific
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 1mg
- 50mg
- 200mg
- 250mg
- 1g
- 1000mg
- 1unit
- 5mg
- 10MG
- 25mg
- 100mg
- 10mM(in 1mL DMSO)
- ManufacturerActivate Scientific
- Product numberAS111957
- Product descriptionCUDC 101 98%
- Packaging5mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerActivate Scientific
- Product numberAS111957
- Product descriptionCUDC 101 98%
- Packaging25mg
- Price$262
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberX7526
- Product descriptionCUDC 101
- Packaging100mg
- Price$395
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000879
- Product descriptionCUDC 101 95.00%
- Packaging5MG
- Price$425
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000879
- Product descriptionCUDC 101 95.00%
- Packaging10MG
- Price$450
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000879
- Product descriptionCUDC 101 95.00%
- Packaging25MG
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4092
- Product descriptionCUDC 101
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4092
- Product descriptionCUDC 101
- Packaging10mg
- Price$75
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4092
- Product descriptionCUDC 101
- Packaging10mM(in 1mL DMSO)
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4092
- Product descriptionCUDC 101
- Packaging50mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4092
- Product descriptionCUDC 101
- Packaging200mg
- Price$770
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0015
- Product descriptionCUDC 101
- Packaging1mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0015
- Product descriptionCUDC 101
- Packaging5mg
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerApolloscientific
- Product numberBIFK0015
- Product descriptionCUDC 101
- Packaging10mg
- Price$149
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60246
- Product descriptionCUDC 101 ≥98%
- Packaging10mg
- Price$168
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546068
- Product descriptionCUDC 101 >98%
- Packaging5mg
- Price$190.4
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Activate Scientific | AS111957 | CUDC 101 98% | 5mg | $108 | 2021-12-16 | Buy |
| Activate Scientific | AS111957 | CUDC 101 98% | 25mg | $262 | 2021-12-16 | Buy |
| AK Scientific | X7526 | CUDC 101 | 100mg | $395 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000879 | CUDC 101 95.00% | 5MG | $425 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000879 | CUDC 101 95.00% | 10MG | $450 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000879 | CUDC 101 95.00% | 25MG | $500 | 2021-12-16 | Buy |
| ApexBio Technology | A4092 | CUDC 101 | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A4092 | CUDC 101 | 10mg | $75 | 2021-12-16 | Buy |
| ApexBio Technology | A4092 | CUDC 101 | 10mM(in 1mL DMSO) | $94 | 2021-12-16 | Buy |
| ApexBio Technology | A4092 | CUDC 101 | 50mg | $290 | 2021-12-16 | Buy |
| ApexBio Technology | A4092 | CUDC 101 | 200mg | $770 | 2021-12-16 | Buy |
| Apolloscientific | BIFK0015 | CUDC 101 | 1mg | $68 | 2021-12-16 | Buy |
| Apolloscientific | BIFK0015 | CUDC 101 | 5mg | $115 | 2021-12-16 | Buy |
| Apolloscientific | BIFK0015 | CUDC 101 | 10mg | $149 | 2021-12-16 | Buy |
| Arctom | CFN60246 | CUDC 101 ≥98% | 10mg | $168 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546068 | CUDC 101 >98% | 5mg | $190.4 | 2021-12-16 | Buy |
Properties
Melting point :174-177℃
Density :1.28
storage temp. :-20°C
solubility :DMSO: soluble
pka :9.47±0.20(Predicted)
form :solid
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PLIVFNIUGLLCEK-UHFFFAOYSA-N
Density :1.28
storage temp. :-20°C
solubility :DMSO: soluble
pka :9.47±0.20(Predicted)
form :solid
color :White or off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :PLIVFNIUGLLCEK-UHFFFAOYSA-N
Safety Information
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Description
CUDC-101 is a multi-target inhibitor, combining functional groups of potent inhibitors of human epidermal growth factor receptor (HER) kinases and histone deacetylases (HDACs). It potently blocks the receptor tyrosine kinases EGFR (aka HER1) and HER2 (IC50s = 2.4 and 16.4 nM, respectively). CUDC-101 also inhibits the activity of class I and class II HDACs at nanomolar concentrations (e.g., IC50s = 4.5, 12.6, 13.2, and 11.4 nM for HDAC1, 2, 4, and 5, respectively). It has only weak effects on over 60 other kinases when tested at 5 μM. CUDC-101 prevents the growth of a wide range of cancer cell lines in vitro, and slows tumor growth or induces tumor regression through cancer cell apoptosis in xenograft models. In cancer cells that have acquired resistance to single-target EGFR inhibitors, CUDC-101 blocks proliferation and reduces cell migration.Related product price
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