U-73343
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- $32 - $757.86
- Product name: U-73343
- CAS: 142878-12-4
- MF: C29H42N2O3
- MW: 466.66
- EINECS:
- MDL Number:MFCD00211221
- Synonyms:U-73343;1-[6-[((17Β)-3-METHOXYESTRA-1,3,5[10]-TRIEN-17-YL)AMINO]HEXYL]-2,5-PYRROLIDINEDIONE;1-[6-((17BETA-3-METHOXYESTRA-1,3,5(10)-TRIEN-17-YL)AMINO)HEXYL]-2,5-PYRROLIDINEDIONE;U-73343;1-[6-[((17β)-3-methoxyestra-1,3,5[10]-trien-17-yl)amino]hexyl]-2,5-pyrrolidinedione;3-Methoxy-17-[6-(2,5-dioxopyrrolidin-1-yl)hexylamino]estra-1,3,5(10)-triene;U73343, U-73343, U 73343;U-73343 - CAS 142878-12-4 - Calbiochem;2,5-Pyrrolidinedione, 1-[6-[[(17β)-3-methoxyestra-1,3,5(10)-trien-17-yl]amino]hexyl]-
27 prices
Selected condition:
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 50
- 10
- 1MG
- 2.5mg
- 5MG
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number4153BA
- Product description1-[6-[[(8R,9S,13S,14S,17S)-3-Methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrolidine-2,5-dione
- Packaging10mg
- Price$268
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0006321
- Product description1-[6-([17BETA-3-METHOXYESTRA-1,3,5 (10)-TRIEN-17-YL]AMINO)HEXYL]-2,5-PYRROLIDINE-DIONE 95.00%
- Packaging5MG
- Price$757.86
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0006321
- Product description1-[6-([17BETA-3-METHOXYESTRA-1,3,5 (10)-TRIEN-17-YL]AMINO)HEXYL]-2,5-PYRROLIDINE-DIONE 95.00%
- Packaging1MG
- Price$671.25
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB9013
- Product descriptionU-73343
- Packaging25mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB9013
- Product descriptionU 73343
- Packaging25mg
- Price$336
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB9013
- Product descriptionU 73343
- Packaging10mg
- Price$168
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB9013
- Product descriptionU-73343
- Packaging10mg
- Price$173
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB9013
- Product descriptionU 73343
- Packaging5mg
- Price$96
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB9013
- Product descriptionU-73343
- Packaging5mg
- Price$104
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17339
- Product descriptionU-73343 ≥95%
- Packaging10mg
- Price$153
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17339
- Product descriptionU-73343 ≥95%
- Packaging5mg
- Price$103
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17339
- Product descriptionU-73343 ≥95%
- Packaging1mg
- Price$36
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17339
- Product descriptionU-73343 ≥95%
- Packaging10mg
- Price$169
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17339
- Product descriptionU-73343 ≥95%
- Packaging25mg
- Price$343
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17339
- Product descriptionU-73343 ≥95%
- Packaging25mg
- Price$378
- Updated2026-04-30
- Buy
- ManufacturerCayman Chemical
- Product number17339
- Product descriptionU-73343 ≥95%
- Packaging5mg
- Price$93
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4153BA | 1-[6-[[(8R,9S,13S,14S,17S)-3-Methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]amino]hexyl]pyrrolidine-2,5-dione | 10mg | $268 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0006321 | 1-[6-([17BETA-3-METHOXYESTRA-1,3,5 (10)-TRIEN-17-YL]AMINO)HEXYL]-2,5-PYRROLIDINE-DIONE 95.00% | 5MG | $757.86 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0006321 | 1-[6-([17BETA-3-METHOXYESTRA-1,3,5 (10)-TRIEN-17-YL]AMINO)HEXYL]-2,5-PYRROLIDINE-DIONE 95.00% | 1MG | $671.25 | 2021-12-16 | Buy |
| ApexBio Technology | B9013 | U-73343 | 25mg | $390 | 2021-12-16 | Buy |
| ApexBio Technology | B9013 | U 73343 | 25mg | $336 | 2026-05-06 | Buy |
| ApexBio Technology | B9013 | U 73343 | 10mg | $168 | 2026-05-06 | Buy |
| ApexBio Technology | B9013 | U-73343 | 10mg | $173 | 2021-12-16 | Buy |
| ApexBio Technology | B9013 | U 73343 | 5mg | $96 | 2026-05-06 | Buy |
| ApexBio Technology | B9013 | U-73343 | 5mg | $104 | 2021-12-16 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 10mg | $153 | 2024-03-01 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 5mg | $103 | 2026-04-30 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 1mg | $36 | 2026-04-30 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 10mg | $169 | 2026-04-30 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 25mg | $343 | 2024-03-01 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 25mg | $378 | 2026-04-30 | Buy |
| Cayman Chemical | 17339 | U-73343 ≥95% | 5mg | $93 | 2024-03-01 | Buy |
Properties
Boiling point :641.5±55.0 °C(Predicted)
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :+15C to +30C
solubility :ethanol: 0.93 mg/mL
pka :10.68±0.40(Predicted)
form :powder
color :white
Stability :Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.
InChIKey :CJHWFIUASFBCKN-ZRJUGLEFSA-N
SMILES :[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OC)ccc24)NCCCCCCN5C(=O)CCC5=O
Density :1.15±0.1 g/cm3(Predicted)
storage temp. :+15C to +30C
solubility :ethanol: 0.93 mg/mL
pka :10.68±0.40(Predicted)
form :powder
color :white
Stability :Stable for 1 year from date of purchase as supplied. Dried films prepared from chloroform solution are stable for at least 1 month at -20°. It is preferable to dissolve U-73343 immediately before use if at all possible. Use caution and retest potency if attempting.
InChIKey :CJHWFIUASFBCKN-ZRJUGLEFSA-N
SMILES :[H][C@]12CC[C@]3(C)[C@H](CC[C@@]3([H])[C@]1([H])CCc4cc(OC)ccc24)NCCCCCCN5C(=O)CCC5=O
Safety Information
| Symbol(GHS): |
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
U-73122 is an inhibitor of PLC-dependent processes, however, the mechanism of action remains unclear. The IC50 values for inhibition of platelet aggregation induced by collagen or thrombin are 0.6 and 5 μM, respectively. It also exhibits inhibitory activity against HIV-1 integrase with an IC50 value of 7 μM. U-73343 is a close structural analog of U-73122 that does not inhibit PLC, making it useful as a negative control for PLC inhibition.Related product price
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