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ChemicalBook >> CAS DataBase List >> UCPH-101

UCPH-101

UCPH-101 price.
  • $10 - $1950
  • Product name: UCPH-101
  • CAS: 1118460-77-7
  • MF: C27H22N2O3
  • MW: 422.48
  • EINECS:
  • MDL Number:
  • Synonyms:UCPH-101;2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile;4H-1-Benzopyran-3-carbonitrile, 2-aMino-5,6,7,8-tetrahydro-4-(4-Methoxyphenyl)-7-(1-naphthalenyl)-5-oxo-;2-Amino-4-(4-methoxy-phenyl)-7-naphthalen-1-yl-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile;UCPH-101; UCPH 101; UCPH101;CS-2757;2-amino-4-(4-methoxyphenyl)-7-(naphthalene-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile;inhibit,UCPH101,UCPH-101,Inhibitor
Price46 Properties Safety Information Description
46 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • Arctom
  • Biosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
  • TRC
Package
  • 500μg
  • 2mg
  • 10mM*1mLinDMSO(Solution)
  • 10mM*1mLinDMSO
  • 10
  • 50
  • 250mg
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1G
  • Manufactureraablocks
  • Product numberAA007RI8
  • Product description2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98%
  • Packaging1mg
  • Price$10
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007RI8
  • Product description2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98%
  • Packaging5mg
  • Price$11
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007RI8
  • Product description2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98%
  • Packaging10mg
  • Price$19
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007RI8
  • Product description2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 98%
  • Packaging25mg
  • Price$36
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007RI8
  • Product description2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98%
  • Packaging50mg
  • Price$60
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA007RI8
  • Product description2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98%
  • Packaging100mg
  • Price$108
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65805
  • Product description2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 98%
  • Packaging100MG
  • Price$160
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberQ65805
  • Product description2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 98%
  • Packaging1G
  • Price$960
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number4503DC
  • Product description2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-YL)-5-oxo-4H-chromene-3-carbonitrile
  • Packaging1mg
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA673822
  • Product descriptionUCPH-101 97%
  • Packaging5mg
  • Price$272
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA673822
  • Product descriptionUCPH-101 97%
  • Packaging25mg
  • Price$646
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA673822
  • Product descriptionUCPH-101 97%
  • Packaging10mg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA673822
  • Product descriptionUCPH-101 97%
  • Packaging100mg
  • Price$1426
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0009873
  • Product description2-AMINO-5,6,7,8-TETRAHYDRO-4-(4-METHOXYPHENYL)-7-(1-NAPHTHALENYL)-5-OXO-4H-1-BENZOPYRAN-3-CARBONITRILE 95.00%
  • Packaging5MG
  • Price$501.69
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-10914
  • Product descriptionUCPH-101 98.61%
  • Packaging25mg
  • Price$523
  • Updated2026-05-26
  • Buy
  • ManufacturerArctom
  • Product numberHY-10914
  • Product descriptionUCPH-101 98.61%
  • Packaging50mg
  • Price$836
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA007RI8 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98% 1mg $10 2026-05-28 Buy
aablocks AA007RI8 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98% 5mg $11 2026-05-28 Buy
aablocks AA007RI8 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98% 10mg $19 2026-05-28 Buy
aablocks AA007RI8 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 98% 25mg $36 2026-05-28 Buy
aablocks AA007RI8 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98% 50mg $60 2026-05-28 Buy
aablocks AA007RI8 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile ≥98% 100mg $108 2026-05-28 Buy
ACHEMBLOCK Q65805 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 98% 100MG $160 2026-05-27 Buy
ACHEMBLOCK Q65805 2-amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile 98% 1G $960 2026-05-27 Buy
AK Scientific 4503DC 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-YL)-5-oxo-4H-chromene-3-carbonitrile 1mg $225 2021-12-16 Buy
Ambeed A673822 UCPH-101 97% 5mg $272 2021-12-16 Buy
Ambeed A673822 UCPH-101 97% 25mg $646 2021-12-16 Buy
Ambeed A673822 UCPH-101 97% 10mg $380 2021-12-16 Buy
Ambeed A673822 UCPH-101 97% 100mg $1426 2021-12-16 Buy
American Custom Chemicals Corporation INB0009873 2-AMINO-5,6,7,8-TETRAHYDRO-4-(4-METHOXYPHENYL)-7-(1-NAPHTHALENYL)-5-OXO-4H-1-BENZOPYRAN-3-CARBONITRILE 95.00% 5MG $501.69 2021-12-16 Buy
Arctom HY-10914 UCPH-101 98.61% 25mg $523 2026-05-26 Buy
Arctom HY-10914 UCPH-101 98.61% 50mg $836 2026-05-26 Buy
Next Last

Properties

Melting point :194.0-197.2 °C
Boiling point :703.5±60.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :Soluble in DMSO (up to 10 mg/ml).
form :solid
pka :3.23±0.60(Predicted)
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

UCPH-101 is a noncompetitive inhibitor of excitatory amino acid transporter 1 (EAAT1), which takes up extracellular glutamate in the central nervous system. UCPH-1 is selective for EAAT1 over EAAT2 and EAAT3 with IC50 values of 0.66, >300, and >300 μM, respectively, in a radioligand uptake assay using HEK293 cells transfected with the human transporter. It selectively inhibits anion currents in tsA201 cells expressing human EAAT1 (Kd = 0.34 μM) over rat EAAT4 and mouse EAAT5 at concentrations up to 10 μM. UCPH-101 is orally bioavailable in rats at a dose of 10 mg/kg but does not cross the blood-brain barrier.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. 3B Pharmachem (Wuhan) International Co.,Ltd. Ascent Scientific Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. Guangzhou Isun Pharmaceutical Co., Ltd Bide Pharmatech Ltd. AdooQ Bioscience CHINA Shanghai Lollane Biological Technology Co.,Ltd. Shanghai EFE Biological Technology Co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd.