Welcome to chemicalbook!

010-86108875

18162-48-6 872-50-4 Methylene Chloride naphthalene THF Titanium Dioxide

Structure Search

RFQ

Try our best to find the right business for you.

Messages

Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> URMC-099

URMC-099

$14 - $1900
Product name: URMC-099
CAS: 1229582-33-5
MF: C27H27N5
MW: 421.54
EINECS:
MDL Number:MFCD28168077
Synonyms:3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine URMC-099;URMC-099;3-(1H-indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine;1H-?Pyrrolo[2,?3-?b]?pyridine, 3-?(1H-?indol-?5-?yl)?-?5-?[4-?[(4-?methyl-?1-?piperazinyl)?methyl]?phenyl]?-;CS-1776;URMC-099;URMC 099;RMC099;inhibit,MLKs,Autophagy,URMC 099,URMC099,URMC-099,Inhibitor,Mixed Lineage Kinase

Price58 Properties Safety Information Description

58 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
Adipogen Life Sciences
AK Scientific
ApexBio Technology
Apolloscientific
Arctom
AvaChem
Biosynth
Cayman Chemical
Chemenu
ChemScene
Crysdot
DC Chemicals
Medical Isotopes, Inc.
TRC

Package

10mM*1mLinDMSO(Solution)
10mM(1mLinDMSO)
10mM(in1mLDMSO)
10mM*1mLinDMSO(Solid+Solvent)
250mg
10mM*1mLinDMSO
2mg
10mM(in 1mL DMSO)
1mg
5mg
10mg
25mg
50mg
100MG
1G

Manufactureraablocks
Product numberAA009CHR
Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
Packaging1mg
Price$14
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CHR
Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
Packaging5mg
Price$27
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CHR
Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
Packaging10mg
Price$37
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CHR
Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
Packaging25mg
Price$61
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA009CHR
Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
Packaging50mg
Price$102
Updated2026-05-28
Buy

ManufacturerACHEMBLOCK
Product numberM15771
Product descriptionURMC-099 98%
Packaging25MG
Price$65
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberM15771
Product descriptionURMC-099 98%
Packaging100MG
Price$180
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberM15771
Product descriptionURMC-099 98%
Packaging1G
Price$1180
Updated2026-05-27
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1211-M010
Product descriptionURMC-099 ≥95%(HPLC)
Packaging10mg
Price$302
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1211-M005
Product descriptionURMC-099 ≥95%(HPLC)
Packaging5mg
Price$194
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1211-M050
Product descriptionURMC-099 ≥95%(HPLC)
Packaging50mg
Price$1026
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1211-M100
Product descriptionURMC-099 ≥95%(HPLC)
Packaging100mg
Price$1782
Updated2021-12-16
Buy

ManufacturerAdipogen Life Sciences
Product numberSYN-1211-M001
Product descriptionURMC-099 ≥95%(HPLC)
Packaging1mg
Price$108
Updated2026-05-06
Buy

ManufacturerAK Scientific
Product numberX3562
Product descriptionURMC-099
Packaging10mg
Price$172
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberSYN1211
Product descriptionURMC-099
Packaging5mg
Price$200
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberB4877
Product descriptionURMC-099
Packaging100mg
Price$715
Updated2026-05-06
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA009CHR	3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%	1mg	$14	2026-05-28	Buy
aablocks	AA009CHR	3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%	5mg	$27	2026-05-28	Buy
aablocks	AA009CHR	3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%	10mg	$37	2026-05-28	Buy
aablocks	AA009CHR	3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%	25mg	$61	2026-05-28	Buy
aablocks	AA009CHR	3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%	50mg	$102	2026-05-28	Buy
ACHEMBLOCK	M15771	URMC-099 98%	25MG	$65	2026-05-27	Buy
ACHEMBLOCK	M15771	URMC-099 98%	100MG	$180	2026-05-27	Buy
ACHEMBLOCK	M15771	URMC-099 98%	1G	$1180	2026-05-27	Buy
Adipogen Life Sciences	SYN-1211-M010	URMC-099 ≥95%(HPLC)	10mg	$302	2026-05-06	Buy
Adipogen Life Sciences	SYN-1211-M005	URMC-099 ≥95%(HPLC)	5mg	$194	2026-05-06	Buy
Adipogen Life Sciences	SYN-1211-M050	URMC-099 ≥95%(HPLC)	50mg	$1026	2026-05-06	Buy
Adipogen Life Sciences	SYN-1211-M100	URMC-099 ≥95%(HPLC)	100mg	$1782	2021-12-16	Buy
Adipogen Life Sciences	SYN-1211-M001	URMC-099 ≥95%(HPLC)	1mg	$108	2026-05-06	Buy
AK Scientific	X3562	URMC-099	10mg	$172	2021-12-16	Buy
AK Scientific	SYN1211	URMC-099	5mg	$200	2021-12-16	Buy
ApexBio Technology	B4877	URMC-099	100mg	$715	2026-05-06	Buy

Next Last

Properties

Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :13.49±0.40(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :QKKIWEILHCXECO-UHFFFAOYSA-N
SMILES :C12NC=C(C3C=CC4=C(C=3)C=CN4)C1=CC(C1=CC=C(CN3CCN(C)CC3)C=C1)=CN=2

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

URMC-099 is an orally bioavailable, brain-penetrant inhibitor of mixed-lineage kinases (MLKs) with IC50 values of 19, 42, 14, and 150 nM for MLK1, MLK2, MLK3, and the related MLK family member DLK, respectively. It also inhibits LRRK2 activity with an IC50 value of 11 nM. In vitro, URMC-099 has been shown to reduce inflammatory cytokine production by HIV-1 Tat-exposed microglia and to prevent destruction and phagocytosis of cultured neuronal axons by these cells. In rodent models of HIV-associated neurocognitive disorders, URMC-099 demonstrates anti-inflammatory and neuroprotective effects.

More related product prices

SKI II AT7867 Erlotinib hydrochloride 252916-29-3 1355326-35-0 Bosutinib (S)-3-(aMinoMethyl)-7-(3-hydroxypropoxy)benzo[c][1,2]oxaborol-1(3H)-ol 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine UNBS-5162 1048371-03-4 Ibrutinib ACP196 Elafibranor(GFT505) PF-01367338 CC-223

Suppliers and manufacturers

Nanjing XiZe Biotechnology CO., Ltd. Shanghai Boyle Chemical Co., Ltd. Dalian Meilun Biotech Co., Ltd. Shanghai Topbiochem Technology Co., Ltd Haoyuan Chemexpress Co., Ltd. Bide Pharmatech Ltd. AdooQ Bioscience CHINA Shanghai Lollane Biological Technology Co.,Ltd. Tongling HengYou Biotechnology Co., Ltd. Shanghaizehan biopharma technology co., Ltd.

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

URMC-099

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers