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ChemicalBook >> CAS DataBase List >> URMC-099

URMC-099

URMC-099 price.
  • $14 - $1900
  • Product name: URMC-099
  • CAS: 1229582-33-5
  • MF: C27H27N5
  • MW: 421.54
  • EINECS:
  • MDL Number:MFCD28168077
  • Synonyms:3-(1H-indol-5-yl)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine URMC-099;URMC-099;3-(1H-indol-5-yl)-5-[4-[(4-methyl-1-piperazinyl)methyl]phenyl]-1H-pyrrolo[2,3-b]pyridine;1H-?Pyrrolo[2,?3-?b]?pyridine, 3-?(1H-?indol-?5-?yl)?-?5-?[4-?[(4-?methyl-?1-?piperazinyl)?methyl]?phenyl]?-;CS-1776;URMC-099;URMC 099;RMC099;inhibit,MLKs,Autophagy,URMC 099,URMC099,URMC-099,Inhibitor,Mixed Lineage Kinase
Price72 Properties Safety Information Description
72 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • Adipogen Life Sciences
  • AK Scientific
  • ApexBio Technology
  • Apolloscientific
  • Arctom
  • AvaChem
  • Biosynth
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • TRC
Package
  • 10mM*1mLinDMSO(Solid+Solvent)
  • 10mM*1mLinDMSO(Solution)
  • 10mM(in1mLDMSO)
  • 10mM(1mLinDMSO)
  • 10mM*1mLinDMSO
  • 2mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100MG
  • 1G
  • Manufactureraablocks
  • Product numberAA009CHR
  • Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
  • Packaging25mg
  • Price$61
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CHR
  • Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
  • Packaging50mg
  • Price$102
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CHR
  • Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
  • Packaging10mg
  • Price$37
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CHR
  • Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
  • Packaging5mg
  • Price$27
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA009CHR
  • Product description3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99%
  • Packaging1mg
  • Price$14
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15771
  • Product descriptionURMC-099 98%
  • Packaging25MG
  • Price$65
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15771
  • Product descriptionURMC-099 98%
  • Packaging25MG
  • Price$65
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15771
  • Product descriptionURMC-099 98%
  • Packaging1G
  • Price$1180
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15771
  • Product descriptionURMC-099 98%
  • Packaging1G
  • Price$1180
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15771
  • Product descriptionURMC-099 98%
  • Packaging100MG
  • Price$180
  • Updated2026-05-25
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberM15771
  • Product descriptionURMC-099 98%
  • Packaging100MG
  • Price$180
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1211-M005
  • Product descriptionURMC-099 ≥95%(HPLC)
  • Packaging5mg
  • Price$194
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1211-M005
  • Product descriptionURMC-099 ≥95%(HPLC)
  • Packaging5mg
  • Price$194
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1211-M001
  • Product descriptionURMC-099 ≥95%(HPLC)
  • Packaging1mg
  • Price$108
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1211-M100
  • Product descriptionURMC-099 ≥95%(HPLC)
  • Packaging100mg
  • Price$1782
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-1211-M050
  • Product descriptionURMC-099 ≥95%(HPLC)
  • Packaging50mg
  • Price$1026
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA009CHR 3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99% 25mg $61 2026-05-28 Buy
aablocks AA009CHR 3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99% 50mg $102 2026-05-28 Buy
aablocks AA009CHR 3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99% 10mg $37 2026-05-28 Buy
aablocks AA009CHR 3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99% 5mg $27 2026-05-28 Buy
aablocks AA009CHR 3-(1H-Indol-5-yl)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridine 99% 1mg $14 2026-05-28 Buy
ACHEMBLOCK M15771 URMC-099 98% 25MG $65 2026-05-27 Buy
ACHEMBLOCK M15771 URMC-099 98% 25MG $65 2026-05-25 Buy
ACHEMBLOCK M15771 URMC-099 98% 1G $1180 2026-05-25 Buy
ACHEMBLOCK M15771 URMC-099 98% 1G $1180 2026-05-27 Buy
ACHEMBLOCK M15771 URMC-099 98% 100MG $180 2026-05-25 Buy
ACHEMBLOCK M15771 URMC-099 98% 100MG $180 2026-05-27 Buy
Adipogen Life Sciences SYN-1211-M005 URMC-099 ≥95%(HPLC) 5mg $194 2021-12-16 Buy
Adipogen Life Sciences SYN-1211-M005 URMC-099 ≥95%(HPLC) 5mg $194 2026-05-06 Buy
Adipogen Life Sciences SYN-1211-M001 URMC-099 ≥95%(HPLC) 1mg $108 2026-05-06 Buy
Adipogen Life Sciences SYN-1211-M100 URMC-099 ≥95%(HPLC) 100mg $1782 2021-12-16 Buy
Adipogen Life Sciences SYN-1211-M050 URMC-099 ≥95%(HPLC) 50mg $1026 2026-05-06 Buy
Next Last

Properties

Density :1.256±0.06 g/cm3(Predicted)
storage temp. :-20°C
solubility :Soluble in DMSO (>25 mg/ml)
form :solid
pka :13.49±0.40(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.
InChIKey :QKKIWEILHCXECO-UHFFFAOYSA-N
SMILES :C12NC=C(C3C=CC4=C(C=3)C=CN4)C1=CC(C1=CC=C(CN3CCN(C)CC3)C=C1)=CN=2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

URMC-099 is an orally bioavailable, brain-penetrant inhibitor of mixed-lineage kinases (MLKs) with IC50 values of 19, 42, 14, and 150 nM for MLK1, MLK2, MLK3, and the related MLK family member DLK, respectively. It also inhibits LRRK2 activity with an IC50 value of 11 nM. In vitro, URMC-099 has been shown to reduce inflammatory cytokine production by HIV-1 Tat-exposed microglia and to prevent destruction and phagocytosis of cultured neuronal axons by these cells. In rodent models of HIV-associated neurocognitive disorders, URMC-099 demonstrates anti-inflammatory and neuroprotective effects.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
URMC-099
$52.00
URMC-099 CAS:1229582-33-5
ATK CHEMICAL COMPANY LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Chemia Biotechnology（Shanghai） Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited
Hangzhou MolCore BioPharmatech Co.,Ltd.
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
ShenZhen Trendseen Biological Technology Co.,Ltd.
Wuhan Topule Biopharmaceutical Co., Ltd