Elafibranor(GFT505)
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- $32 - $750
- Product name: Elafibranor(GFT505)
- CAS: 923978-27-2
- MF: C22H24O4S
- MW: 384.49
- EINECS:-0
- MDL Number:
- Synonyms:Elafibranor(GFT505);elafibranor E;Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-;2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid;(E)-2-(2,6-dimethyl-4-(3-(4-(methylthio)phenyl)-3-oxoprop-1-en-1-yl)phenoxy)-2-methylpropanoic acid;SureCN815512;Elafibranor (GFT-505, Ph III);GFT505(ELAFIBRANOR)
11 prices
Selected condition：
Brand
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 100mg
- 250mg
- ManufacturerBiosynth Carbosynth
- Product numberBE163306
- Product descriptionElafibranor
- Packaging25mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberBE163306
- Product descriptionElafibranor
- Packaging100mg
- Price$140
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number23508
- Product descriptionElafibranor ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23508
- Product descriptionElafibranor ≥98%
- Packaging5mg
- Price$116
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number23508
- Product descriptionElafibranor ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-5522
- Product descriptionElafibranor 99.18%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5522
- Product descriptionElafibranor 99.18%
- Packaging10mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-5522
- Product descriptionElafibranor 99.18%
- Packaging25mg
- Price$285
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC10727
- Product descriptionElafibranor(GFT505) >98%
- Packaging250mg
- Price$750
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number95174
- Product descriptionElafibranor
- Packaging25mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberG368870
- Product descriptionGFT-505
- Packaging25mg
- Price$65
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Biosynth Carbosynth | BE163306 | Elafibranor | 25mg | $50 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BE163306 | Elafibranor | 100mg | $140 | 2021-12-16 | Buy |
| Cayman Chemical | 23508 | Elafibranor ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 23508 | Elafibranor ≥98% | 5mg | $116 | 2024-03-01 | Buy |
| Cayman Chemical | 23508 | Elafibranor ≥98% | 10mg | $184 | 2024-03-01 | Buy |
| ChemScene | CS-5522 | Elafibranor 99.18% | 5mg | $72 | 2021-12-16 | Buy |
| ChemScene | CS-5522 | Elafibranor 99.18% | 10mg | $120 | 2021-12-16 | Buy |
| ChemScene | CS-5522 | Elafibranor 99.18% | 25mg | $285 | 2021-12-16 | Buy |
| DC Chemicals | DC10727 | Elafibranor(GFT505) >98% | 250mg | $750 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 95174 | Elafibranor | 25mg | $190 | 2021-12-16 | Buy |
| TRC | G368870 | GFT-505 | 25mg | $65 | 2021-12-16 | Buy |
Properties
Boiling point :569.0±50.0 °C(Predicted)
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :3.30±0.11(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Density :1.21±0.1 g/cm3(Predicted)
storage temp. :-20°
solubility :Soluble in DMSO (up to at least 25 mg/ml).
form :solid
pka :3.30±0.11(Predicted)
color :Pale yellow
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Safety Information
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Description
Elafibranor is an agonist of the peroxisome proliferator-activated receptors (PPAR) α and δ. It increases HDL secretion and expression of the lipid-related genes ABCA1, PLIN2, and ABHD5 in Caco-2/TC7 cells in a PPARα-dependent manner. Elafibranor (10 mg/kg) decreases levels of plasma triglycerides and total cholesterol while increasing plasma HDL and expression of Acox1, a PPARα target gene, in the liver of ApoE2-KI wild-type, but not PPARα knockout, mice fed a Western diet. However, PPARα knockout mice exhibit a decrease in plasma total and non-HDL cholesterol levels, indicating PPARδ has a role in these functions. Elafibranor (30 mg/kg) reduces diet-induced macro- and micro-steatosis in a PPARα-deficient mouse model of non-alcoholic steatohepatitis. It also reduces cholesterol and triglyceride accumulation as well as macrovesicular steatosis in the liver of insulin-resistant db/db mice fed the methionine-choline deficient (MCD) diet. Formulations containing elafibranor are under clinical investigation for the treatment of non-alcoholic steatohepatitis.Related product price
Suppliers and manufacturers
ENBRIDGE PHARMTECH CO., LTD.
Nanjing ChemLin Chemical Industry Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Shandong chuangyingchemical Co., Ltd.
BOC Sciences
Chongqing Chemdad Co., Ltd
Wuxi Rejoys chemical Technology Co., Ltd.
Dideu Industries Group Limited
