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ChemicalBook >> CAS DataBase List >> VX-661

VX-661

VX-661 price.
  • $55 - $950
  • Product name: VX-661
  • CAS: 1152311-62-0
  • MF: C26H27F3N2O6
  • MW: 520.5
  • EINECS:
  • MDL Number:MFCD23106064
  • Synonyms:VX-661;VX-661/VX661;1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide;Cyclopropanecarboxamide, 1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-;1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide VX661;(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-;CS-956;VX661/Tezacaftor
Price27 Properties Safety Information Description
27 prices
Selected condition：
Brand
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 10mM(in 1mL DMSO)
  • 25mg
  • 50mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • ManufacturerAK Scientific
  • Product numberY0430
  • Product description(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
  • Packaging100mg
  • Price$428
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0430
  • Product description(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
  • Packaging250mg
  • Price$725
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2664
  • Product descriptionVX-661
  • Packaging5mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2664
  • Product descriptionVX-661
  • Packaging10mM(in 1mL DMSO)
  • Price$115
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2664
  • Product descriptionVX-661
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2664
  • Product descriptionVX-661
  • Packaging50mg
  • Price$440
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60264
  • Product descriptionTezacaftor(VX-661)
  • Packaging10mg
  • Price$338
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD104056
  • Product descriptionTezacaftor
  • Packaging25mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD104056
  • Product descriptionTezacaftor
  • Packaging50mg
  • Price$175
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD104056
  • Product descriptionTezacaftor
  • Packaging100mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD104056
  • Product descriptionTezacaftor
  • Packaging250mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFD104056
  • Product descriptionTezacaftor
  • Packaging500mg
  • Price$750
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number21480
  • Product descriptionVX-661 ≥98%
  • Packaging5mg
  • Price$62
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21480
  • Product descriptionVX-661 ≥98%
  • Packaging10mg
  • Price$115
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21480
  • Product descriptionVX-661 ≥98%
  • Packaging25mg
  • Price$239
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number21480
  • Product descriptionVX-661 ≥98%
  • Packaging50mg
  • Price$448
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0430 (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide 100mg $428 2021-12-16 Buy
AK Scientific Y0430 (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide 250mg $725 2021-12-16 Buy
ApexBio Technology A2664 VX-661 5mg $100 2021-12-16 Buy
ApexBio Technology A2664 VX-661 10mM(in 1mL DMSO) $115 2021-12-16 Buy
ApexBio Technology A2664 VX-661 10mg $150 2021-12-16 Buy
ApexBio Technology A2664 VX-661 50mg $440 2021-12-16 Buy
Arctom CFN60264 Tezacaftor(VX-661) 10mg $338 2021-12-16 Buy
Biosynth Carbosynth FD104056 Tezacaftor 25mg $100 2021-12-16 Buy
Biosynth Carbosynth FD104056 Tezacaftor 50mg $175 2021-12-16 Buy
Biosynth Carbosynth FD104056 Tezacaftor 100mg $280 2021-12-16 Buy
Biosynth Carbosynth FD104056 Tezacaftor 250mg $500 2021-12-16 Buy
Biosynth Carbosynth FD104056 Tezacaftor 500mg $750 2021-12-16 Buy
Cayman Chemical 21480 VX-661 ≥98% 5mg $62 2024-03-01 Buy
Cayman Chemical 21480 VX-661 ≥98% 10mg $115 2024-03-01 Buy
Cayman Chemical 21480 VX-661 ≥98% 25mg $239 2024-03-01 Buy
Cayman Chemical 21480 VX-661 ≥98% 50mg $448 2024-03-01 Buy
Next Last

Properties

Boiling point :610.8±55.0 °C(Predicted)
Density :1.49±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C , stored under nitrogen
solubility :≥21.8 mg/mL in DMSO; insoluble in EtOH; ≥24.3 mg/mL in H2O
form :solid
pka :13.99±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Tezacaftor (VX-661) is an oral medication for cystic fibrosis (CF) developed by Vertex Pharmaceuticals. In a combination therapy formulation called Symdeko (tezacaftor plus ivacaftor), it is approved in the U.S. and Canada for CF patients, ages 12 and older, who have two copies of the F508del mutation in the CFTR gene and one minimal function mutation. Symdeko is approved and marketed in the EU as Symkevi.Tezacaftor is not approved as a stand-alone treatment, but as part of a combination therapy.

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Suppliers and manufacturers

career henan chemical co
VX-661
$8.00 /1kg
VX-661 CAS: 1152311-62-0
Hangzhou FandaChem Co.,Ltd.
Biochempartner
BOC Sciences
Chongqing Chemdad Co., Ltd
ENBRIDGE PHARMTECH CO., LTD.
Zhengzhou Alfa Chemical Co.,Ltd
TargetMol Chemicals Inc.
Allfluoro pharmaceutical co. ltd.
HANGZHOU CLAP TECHNOLOGY CO.,LTD