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ChemicalBook >> CAS DataBase List >> PLX-4720

PLX-4720

$30 - $1133.9
Product name: PLX-4720
CAS: 918505-84-7
MF: C17H14ClF2N3O3S
MW: 413.83
EINECS:
MDL Number:MFCD14635203
Synonyms:1-PropanesulfonaMide, N-[3-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-;N-[3-[(5-Chloro-1H-pyrrol...;N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide PLX 4720;PLX 4720 N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide;PLX4720, >=98%;Raf Kinase Inhibitor V;PLX-4720, N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide;N-(3-(5-Chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamide

Price33 Properties Safety Information Description

33 prices

Selected condition：

Brand

Adipogen Life Sciences
AK Scientific
ApexBio Technology
Arctom
Axon Medchem
Biorbyt Ltd
Biosynth Carbosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
Usbiological

Package

2mg
5mg
50mg
100mg
250mg
1g
1mg
10mM(in1mLDMSO)
10mg
25mg
10mM(in 1mL DMSO)
EvaluationSample

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-3577-M005
Product descriptionPLX4720 ≥99%(HPLC)
Packaging5mg
Price$50
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-3577-M025
Product descriptionPLX4720 ≥99%(HPLC)
Packaging25mg
Price$150
Updated2026-05-06
Buy

ManufacturerAdipogen Life Sciences
Product numberAG-CR1-3577-M025
Product descriptionPLX4720 ≥99%(HPLC)
Packaging25mg
Price$255
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product numberX7406
Product descriptionPLX-4720
Packaging5mg
Price$60
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3016
Product descriptionPLX-4720
Packaging10mM(in1mLDMSO)
Price$61
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3016
Product descriptionPLX-4720
Packaging10mg
Price$71
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3016
Product descriptionPLX-4720
Packaging10mM(in 1mL DMSO)
Price$90
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA3016
Product descriptionPLX-4720
PackagingEvaluationSample
Price$30
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3016
Product descriptionPLX-4720
Packaging25mg
Price$103
Updated2026-05-06
Buy

ManufacturerApexBio Technology
Product numberA3016
Product descriptionPLX-4720
Packaging100mg
Price$233
Updated2026-05-06
Buy

ManufacturerArctom
Product numberCFN60059
Product descriptionPLX-4720 ≥98%
Packaging10mg
Price$168
Updated2021-12-16
Buy

ManufacturerAxon Medchem
Product numberAxon1474
Product descriptionPLX4720 99%
Packaging2mg
Price$55
Updated2021-12-16
Buy

ManufacturerBiorbyt Ltd
Product numberorb154747
Product descriptionPLX-4720 >99%
Packaging100mg
Price$510
Updated2021-12-16
Buy

ManufacturerBiorbyt Ltd
Product numberorb154747
Product descriptionPLX-4720 >99%
Packaging250mg
Price$615.4
Updated2021-12-16
Buy

ManufacturerBiorbyt Ltd
Product numberorb154747
Product descriptionPLX-4720 >99%
Packaging1g
Price$1133.9
Updated2021-12-16
Buy

ManufacturerBiosynth Carbosynth
Product numberFC34125
Product descriptionPLX 4720
Packaging50mg
Price$332.5
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Adipogen Life Sciences	AG-CR1-3577-M005	PLX4720 ≥99%(HPLC)	5mg	$50	2026-05-06	Buy
Adipogen Life Sciences	AG-CR1-3577-M025	PLX4720 ≥99%(HPLC)	25mg	$150	2026-05-06	Buy
Adipogen Life Sciences	AG-CR1-3577-M025	PLX4720 ≥99%(HPLC)	25mg	$255	2021-12-16	Buy
AK Scientific	X7406	PLX-4720	5mg	$60	2021-12-16	Buy
ApexBio Technology	A3016	PLX-4720	10mM(in1mLDMSO)	$61	2026-05-06	Buy
ApexBio Technology	A3016	PLX-4720	10mg	$71	2026-05-06	Buy
ApexBio Technology	A3016	PLX-4720	10mM(in 1mL DMSO)	$90	2021-12-16	Buy
ApexBio Technology	A3016	PLX-4720	EvaluationSample	$30	2026-05-06	Buy
ApexBio Technology	A3016	PLX-4720	25mg	$103	2026-05-06	Buy
ApexBio Technology	A3016	PLX-4720	100mg	$233	2026-05-06	Buy
Arctom	CFN60059	PLX-4720 ≥98%	10mg	$168	2021-12-16	Buy
Axon Medchem	Axon1474	PLX4720 99%	2mg	$55	2021-12-16	Buy
Biorbyt Ltd	orb154747	PLX-4720 >99%	100mg	$510	2021-12-16	Buy
Biorbyt Ltd	orb154747	PLX-4720 >99%	250mg	$615.4	2021-12-16	Buy
Biorbyt Ltd	orb154747	PLX-4720 >99%	1g	$1133.9	2021-12-16	Buy
Biosynth Carbosynth	FC34125	PLX 4720	50mg	$332.5	2021-12-16	Buy

Next Last

Properties

Melting point :230-233oC
Density :1.55
storage temp. :+2C to +8C
solubility :DMSO (Slightly), Methanol (Slightly, Heated)
form :Orange-yellow solid
pka :6.20±0.10(Predicted)
color :White to Off-White

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The Raf kinases activate cellular pathways that lead to cell proliferation and can contribute to certain types of cancer. Mutations in the kinase B-Raf are involved in a wide range of cancers. In particular, the mutation B-RafV600E occurs in melanomas and thyroid cancer but is poorly targeted by many inhibitors of wild type B-Raf. PLX4720 is an orally-available, highly selective inhibitor of B-RafV600E (IC50 = 13 nM). It is less effective against wild type B-Raf (IC50 = 160 nM) as well as several other kinases. PLX4720 induces cell cycle arrest and apoptosis in cells and xenografts expressing the mutant of B-Raf.

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Suppliers and manufacturers

career henan chemical co

$1.00 /1KG
N-[3-[(5-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide CAS:918505-84-7

TargetMol Chemicals Inc.

$48.00 /10mg
PLX-4720 CAS:918505-84-7

Capot Chemical Co.,Ltd.

ATK CHEMICAL COMPANY LIMITED

Shanghai Arbor Chemical Co., Ltd.

Biochempartner

Shenzhen Nexconn Pharmatechs Ltd

CONIER CHEM AND PHARMA LIMITED

Antai Fine Chemical Technology Co.,Limited

Shanghai Gubang New Materail Technology Co. LTD

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PLX-4720

Properties

Safety Information

Description

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