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ChemicalBook >> CAS DataBase List >> VidofludiMus

VidofludiMus

VidofludiMus price.
  • $19 - $818
  • Product name: VidofludiMus
  • CAS: 717824-30-1
  • MF: C20H18FNO4
  • MW: 355.36
  • EINECS:
  • MDL Number:MFCD18633262
  • Synonyms:VidofludiMus;SC12267);VidofludiMus(4SC-101;VIDOFLUDIMUS(4SC-101; SC12267);2-[[(3-Fluoro-3'-methoxy[1,1'-biphenyl]-4-yl)amino]carbonyl]-1-cyclopentene-1-carboxylic acid;2-[(3-Fluoro-3'-methoxy-4-biphenylyl)carbamoyl]-1-cyclopentene-1-carboxylic acid;2-[(3-fluoro-3'-methoxybiphenyl-4-yl)carbamoyl]cyclopent-1-ene-1-carboxylic acid Vidofludimus(4SC-101;CS-1196
24 prices
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  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number3672BB
  • Product descriptionVidofludimus
  • Packaging1mg
  • Price$127
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377932
  • Product description2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+%
  • Packaging1mg
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377932
  • Product description2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+%
  • Packaging5mg
  • Price$43
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377932
  • Product description2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+%
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377932
  • Product description2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+%
  • Packaging25mg
  • Price$96
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377932
  • Product description2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+%
  • Packaging50mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA377932
  • Product description2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+%
  • Packaging100mg
  • Price$215
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0014188
  • Product descriptionVIDOFLUDIMUS 95.00%
  • Packaging5MG
  • Price$320.1
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB4669
  • Product descriptionVidofludimus
  • Packaging100mg
  • Price$640
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2377
  • Product descriptionVidofludimus-4SC-101|SC12267 99%
  • Packaging5mg
  • Price$137.5
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number18377
  • Product descriptionVidofludimus ≥98%
  • Packaging1mg
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18377
  • Product descriptionVidofludimus ≥98%
  • Packaging5mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18377
  • Product descriptionVidofludimus ≥98%
  • Packaging10mg
  • Price$213
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number18377
  • Product descriptionVidofludimus ≥98%
  • Packaging25mg
  • Price$485
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM203863
  • Product description2-((3-fluoro-3''-methoxy-[1,1''-biphenyl]-4-yl)carbamoyl)cyclopent-1-ene-1-carboxylicacid 98%
  • Packaging100mg
  • Price$818
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3221
  • Product descriptionVidofludimus 98.75%
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3672BB Vidofludimus 1mg $127 2021-12-16 Buy
Ambeed A377932 2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+% 1mg $19 2021-12-16 Buy
Ambeed A377932 2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+% 5mg $43 2021-12-16 Buy
Ambeed A377932 2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+% 10mg $65 2021-12-16 Buy
Ambeed A377932 2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+% 25mg $96 2021-12-16 Buy
Ambeed A377932 2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+% 50mg $145 2021-12-16 Buy
Ambeed A377932 2-((3-Fluoro-3'-methoxy-[1,1'-biphenyl]-4-yl)carbamoyl)cyclopent-1-enecarboxylicacid 98+% 100mg $215 2021-12-16 Buy
American Custom Chemicals Corporation API0014188 VIDOFLUDIMUS 95.00% 5MG $320.1 2021-12-16 Buy
ApexBio Technology B4669 Vidofludimus 100mg $640 2021-12-16 Buy
Axon Medchem Axon2377 Vidofludimus-4SC-101|SC12267 99% 5mg $137.5 2021-12-16 Buy
Cayman Chemical 18377 Vidofludimus ≥98% 1mg $37 2024-03-01 Buy
Cayman Chemical 18377 Vidofludimus ≥98% 5mg $116 2024-03-01 Buy
Cayman Chemical 18377 Vidofludimus ≥98% 10mg $213 2024-03-01 Buy
Cayman Chemical 18377 Vidofludimus ≥98% 25mg $485 2024-03-01 Buy
Chemenu CM203863 2-((3-fluoro-3''-methoxy-[1,1''-biphenyl]-4-yl)carbamoyl)cyclopent-1-ene-1-carboxylicacid 98% 100mg $818 2021-12-16 Buy
ChemScene CS-3221 Vidofludimus 98.75% 5mg $90 2021-12-16 Buy

Properties

Boiling point :567.5±50.0 °C(Predicted)
Density :1.354±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :insoluble in H2O; insoluble in EtOH; ≥103 mg/mL in DMSO
form :solid
pka :4?+-.0.20(Predicted)
color :Light yellow to gray
InChI :InChI=1S/C20H18FNO4/c1-26-14-5-2-4-12(10-14)13-8-9-18(17(21)11-13)22-19(23)15-6-3-7-16(15)20(24)25/h2,4-5,8-11H,3,6-7H2,1H3,(H,22,23)(H,24,25)
InChIKey :XPRDUGXOWVXZLL-UHFFFAOYSA-N
SMILES :C1(C(O)=O)CCCC=1C(NC1=CC=C(C2=CC=CC(OC)=C2)C=C1F)=O

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Dihydroorotate dehydrogenase (DHODH) is involved in pyrimidine nucleoside biosynthesis. DHODH inhibitors have value in autoimmune diseases as well as cancer and certain infections. Vidofludimus is an immunosuppressive drug that inhibits DHODH (IC50s = 0.134, 1.29, and 10.6 μM for human, rat, and mouse isoforms, respectively). Through this action, it inhibits the proliferation of T cells and B cells and the secretion of IL-17 (IC50s = 12.9, 3.7, and 6.0 μM, respectively, in human cells). Oral administration of vidofludimus improves both chronic dextran sodium sulfate-induced and acute TNBS-induced colitis in mice.