WEDELOLACTONE
|
- $49 - $859
- Product name: WEDELOLACTONE
- CAS: 524-12-9
- MF: C16H10O7
- MW: 314.25
- EINECS:200-158-5
- MDL Number:MFCD07778564
- Synonyms:1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c][1]benzopyran-6-one;6H-Benzofuro(3,2-C)(1)benzopyran-6-one, 1,8,9-trihydroxy-3-methoxy-;5,11,12-Trihydroxy-7-MethoxycouMestan;1,8,9-trihydroxy-3-Methoxy-6H-benzofuro[3,2-c]chroMen-6-one;IKK Inhibitor II, Wedelolactone ;Wedelia lactone;Wedelolactone;Wedelolactone, ≥98%(HPLC)
37 prices
Selected condition：
Brand
- Adipogen Life Sciences
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 5mg
- 10mg
- 20mg
- y0001599
- 25mg
- 50mg
- 100mg
- 250mg
- 15 mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0424-M001
- Product descriptionWedelolactone ≥98%(HPLC)
- Packaging1mg
- Price$70
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0000124
- Product descriptionWEDELOLACTONE 95.00%
- Packaging1MG
- Price$207.9
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN2131
- Product descriptionWedelolactone
- Packaging20mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN98857
- Product descriptionWedelolactone ≥98%
- Packaging20mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY068303
- Product descriptionWedelolactone,98%,fromWedeliachinensis(Osbeck.)Merr. ≥98%
- Packaging10mg
- Price$196.36
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS021530
- Product description1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one ≥98%
- Packaging25mg
- Price$859
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2429
- Product descriptionWedelolactone
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2429
- Product descriptionWedelolactone
- Packaging20mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2429
- Product descriptionWedelolactone
- Packaging100mg
- Price$390
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2429
- Product descriptionWedelolactone
- Packaging250mg
- Price$690
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105263
- Product descriptionwedelolactone >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFW73945
- Product descriptionWedelolactone
- Packaging5mg
- Price$65
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFW73945
- Product descriptionWedelolactone
- Packaging10mg
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFW73945
- Product descriptionWedelolactone
- Packaging25mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFW73945
- Product descriptionWedelolactone
- Packaging50mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFW73945
- Product descriptionWedelolactone
- Packaging100mg
- Price$350
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CN2-0424-M001 | Wedelolactone ≥98%(HPLC) | 1mg | $70 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000124 | WEDELOLACTONE 95.00% | 1MG | $207.9 | 2021-12-16 | Buy |
| ApexBio Technology | N2131 | Wedelolactone | 20mg | $200 | 2021-12-16 | Buy |
| Arctom | CFN98857 | Wedelolactone ≥98% | 20mg | $128 | 2021-12-16 | Buy |
| Arctom | SY068303 | Wedelolactone,98%,fromWedeliachinensis(Osbeck.)Merr. ≥98% | 10mg | $196.36 | 2021-12-16 | Buy |
| Arctom | AS021530 | 1,8,9-Trihydroxy-3-methoxy-6H-benzofuro[3,2-c]chromen-6-one ≥98% | 25mg | $859 | 2021-12-16 | Buy |
| AvaChem | 2429 | Wedelolactone | 5mg | $65 | 2021-12-16 | Buy |
| AvaChem | 2429 | Wedelolactone | 20mg | $135 | 2021-12-16 | Buy |
| AvaChem | 2429 | Wedelolactone | 100mg | $390 | 2021-12-16 | Buy |
| AvaChem | 2429 | Wedelolactone | 250mg | $690 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105263 | wedelolactone >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FW73945 | Wedelolactone | 5mg | $65 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FW73945 | Wedelolactone | 10mg | $100 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FW73945 | Wedelolactone | 25mg | $160 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FW73945 | Wedelolactone | 50mg | $250 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FW73945 | Wedelolactone | 100mg | $350 | 2021-12-16 | Buy |
Properties
Melting point :327～330℃
Boiling point :498.4±45.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 14 mg/mL, soluble
form :solid
pka :6.90±0.20(Predicted)
color :brown-beige
InChI :InChI=1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
InChIKey :XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES :C1(=O)OC2=CC(OC)=CC(O)=C2C2OC3=CC(O)=C(O)C=C3C1=2
Boiling point :498.4±45.0 °C(Predicted)
Density :1.655±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: 14 mg/mL, soluble
form :solid
pka :6.90±0.20(Predicted)
color :brown-beige
InChI :InChI=1S/C16H10O7/c1-21-6-2-10(19)14-12(3-6)23-16(20)13-7-4-8(17)9(18)5-11(7)22-15(13)14/h2-5,17-19H,1H3
InChIKey :XQDCKJKKMFWXGB-UHFFFAOYSA-N
SMILES :C1(=O)OC2=CC(OC)=CC(O)=C2C2OC3=CC(O)=C(O)C=C3C1=2
Safety Information
| Symbol(GHS): |
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | ||||||||||||||
| Hazard statements: |
|
||||||||||||||
| Precautionary statements: |
|
Description
Wedelolactone is a natural coumestan originally isolated from plants used in herbal therapies. It inhibits NF-κB signaling at the level of IKK action, resulting in suppression of NF-κB-mediated gene expression at concentrations of 1-100 μM. Wedelolactone can also inhibit hepatitis C virus NS5B RNA-dependent RNA polymerase in vitro (IC50 = 36 μM), STAT1 dephosphorylation (50 μM), and EZH2-EED interactions (Kd = 2.8 μM). Prolonged incubation of HepG2 liver cells with wedelolactone alters lipid metabolism through increased expression of AMPK, PPARα, lipoprotein lipase, and low-density lipoprotein receptor.More related product prices
Hypericin 78285-90-2 4-Hydroxycoumarin 2107-76-8 4-METHYLESCULETIN WILFORINE 51059-44-0 Wogonin WILFORLIDE A WITHAFERIN A COUMESTROLRelated product price
- Hypericin
$27-2900 - 78285-90-2
$80-814.97 - 4-Hydroxycoumarin
$23.5-1522.5
Suppliers and manufacturers
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
Nanjing Dolon Biotechnology Co.,Ltd.
BOC Sciences
TopScience Biochemical
CONIER CHEM AND PHARMA LIMITED
