XAP044
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- $32 - $2279
- Product name: XAP044
- CAS: 196928-50-4
- MF: C15H9IO4
- MW: 380.13
- EINECS:
- MDL Number:MFCD00525548
- Synonyms:XAP044;7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one;4H-1-Benzopyran-4-one, 7-hydroxy-3-(4-iodophenoxy)-;7-Hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one;XAP-044,mGlu7,XAP044,neurotransmission,brain exposure,CNS,inhibit,mGluR,antidepressant,Metabotropic glutamate receptors,wide spectrum,anti-stress,Inhibitor,anxiolytic-like,XAP 044
19 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 10
- 1mg
- 5mg
- 10mg
- 50
- 25MG
- 50mg
- 1g
- 2.500g
- 5g
- ManufacturerAK Scientific
- Product number1401CP
- Product description7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number1401CP
- Product description7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one
- Packaging5mg
- Price$226
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberINB0009838
- Product descriptionXAP-044 95.00%
- Packaging5MG
- Price$458.24
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3220
- Product descriptionXAP044
- Packaging5mg
- Price$130
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3220
- Product descriptionXAP044
- Packaging10mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number19095
- Product descriptionXAP044 ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19095
- Product descriptionXAP044 ≥98%
- Packaging5mg
- Price$111
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number19095
- Product descriptionXAP044 ≥98%
- Packaging10mg
- Price$206
- Updated2024-03-01
- Buy
- ManufacturerMatrix Scientific
- Product number135505
- Product description7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one 95%+
- Packaging1g
- Price$692
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number135505
- Product description7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one 95%+
- Packaging2.500g
- Price$1511
- Updated2021-12-16
- Buy
- ManufacturerMatrix Scientific
- Product number135505
- Product description7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one 95%+
- Packaging5g
- Price$2279
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number62626
- Product descriptionXAP044
- Packaging50mg
- Price$1150
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1317
- Product descriptionXAP044 ≥98% (HPLC)
- Packaging5MG
- Price$129
- Updated2022-05-15
- Buy
- ManufacturerSigma-Aldrich
- Product number5.31145
- Product descriptionmGlu7 Antagonist, XAP044 - Calbiochem A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC?? = 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells).
- Packaging10MG
- Price$186
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML1317
- Product descriptionXAP044 ≥98% (HPLC)
- Packaging25MG
- Price$449
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number5248
- Product descriptionXAP044 ≥98%(HPLC)
- Packaging10
- Price$203
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1401CP | 7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one | 1mg | $133 | 2021-12-16 | Buy |
| AK Scientific | 1401CP | 7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one | 5mg | $226 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0009838 | XAP-044 95.00% | 5MG | $458.24 | 2021-12-16 | Buy |
| ApexBio Technology | C3220 | XAP044 | 5mg | $130 | 2021-12-16 | Buy |
| ApexBio Technology | C3220 | XAP044 | 10mg | $243 | 2021-12-16 | Buy |
| Cayman Chemical | 19095 | XAP044 ≥98% | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 19095 | XAP044 ≥98% | 5mg | $111 | 2024-03-01 | Buy |
| Cayman Chemical | 19095 | XAP044 ≥98% | 10mg | $206 | 2024-03-01 | Buy |
| Matrix Scientific | 135505 | 7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one 95%+ | 1g | $692 | 2021-12-16 | Buy |
| Matrix Scientific | 135505 | 7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one 95%+ | 2.500g | $1511 | 2021-12-16 | Buy |
| Matrix Scientific | 135505 | 7-Hydroxy-3-(4-iodophenoxy)-4H-chromen-4-one 95%+ | 5g | $2279 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 62626 | XAP044 | 50mg | $1150 | 2021-12-16 | Buy |
| Sigma-Aldrich | SML1317 | XAP044 ≥98% (HPLC) | 5MG | $129 | 2022-05-15 | Buy |
| Sigma-Aldrich | 5.31145 | mGlu7 Antagonist, XAP044 - Calbiochem A blood-brain barrier permeable, potent, selective, and reversible antagonist of mGlu7 receptor (IC?? = 3.5 and 2.8 μM for mGlu7a and mGlu7b in CHO cells). | 10MG | $186 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML1317 | XAP044 ≥98% (HPLC) | 25MG | $449 | 2024-03-01 | Buy |
| Tocris | 5248 | XAP044 ≥98%(HPLC) | 10 | $203 | 2021-12-16 | Buy |
Properties
Boiling point :485.7±45.0 °C(Predicted)
Density :1.853±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤10mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
form :crystalline solid
pka :6.70±0.20(Predicted)
Density :1.853±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≤10mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
form :crystalline solid
pka :6.70±0.20(Predicted)
Safety Information
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Description
XAP044 is an antagonist of the metabotropic glutamate (mGlu) receptor 7 (mGluR7), inhibiting lateral amygdala long term potentiation in brain slices from wild-type mice with an IC50 value of 88 nM. This effect is absent in mGluR7-deficient mice. XAP044 demonstrates good brain penetrance, producing wide spectrum anti-stress and antidepressant- and anxiolytic-like efficacy in rodent behavioral tests.Suppliers and manufacturers
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