Z-FL-COCHO
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- $42 - $1238
- Product name: Z-FL-COCHO
- CAS: 1373215-15-6
- MF: C25H29FN4O5
- MW: 484.52
- EINECS:
- MDL Number:MFCD04974155
- Synonyms:Z-FL-COCHO;((3R,4S)-4-((4-FLUOROBENZOYL)AMINO)-6-(4-(OXETAN-3-YL)PIPERAZIN-1-YL)CHROMAN-3-YL)N-METHYLCARBAMATE;CATHEPSIN S INHIBITOR;N-[(3R,4S)-3,4-Dihydro-3-[[(methylamino)carbonyl]oxy]-6-[4-(3-oxetanyl)-1-piperazinyl]-2H-1-benzopyran-4-yl]-4-fluorobenzamide;LY 3000328;Benzamide, N-[(3R,4S)-3,4-dihydro-3-[[(methylamino)carbonyl]oxy]-6-[4-(3-oxetanyl)-1-piperazinyl]-2H-1-benzopyran-4-yl]-4-fluoro-;(3R,4S)-4-(4-fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-3-yl methylcarbamate;CATHEPSIN S INHIBITOR ;LY-3000328;LY3000328
23 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- Chemenu
- ChemScene
- Crysdot
- TRC
Package
- 10mM(in 1mL DMSO)
- 500μg
- 1mg
- 2.5mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100mg
- ManufacturerAK Scientific
- Product number3527AH
- Product descriptionCathepsinSinhibitor
- Packaging10mg
- Price$444
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA473978
- Product descriptionLY3000328 98+%
- Packaging1mg
- Price$42
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA473978
- Product descriptionLY3000328 98+%
- Packaging5mg
- Price$92
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA473978
- Product descriptionLY3000328 98+%
- Packaging10mg
- Price$135
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA473978
- Product descriptionLY3000328 98+%
- Packaging25mg
- Price$204
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA473978
- Product descriptionLY3000328 98+%
- Packaging50mg
- Price$304
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA473978
- Product descriptionLY3000328 98+%
- Packaging100mg
- Price$455
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3284
- Product descriptionCathepsinSinhibitor
- Packaging5mg
- Price$212
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3284
- Product descriptionCathepsinSinhibitor
- Packaging10mM(in 1mL DMSO)
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3284
- Product descriptionCathepsinSinhibitor
- Packaging10mg
- Price$275
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number29729
- Product descriptionLY3000328
- Packaging500μg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29729
- Product descriptionLY3000328
- Packaging1mg
- Price$152
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29729
- Product descriptionLY3000328
- Packaging5mg
- Price$356
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number29729
- Product descriptionLY3000328
- Packaging10mg
- Price$632
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM162803
- Product description(3R,4S)-4-(4-fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-3-ylmethylcarbamate 98%
- Packaging50mg
- Price$628
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-1120
- Product descriptionLY3000328 99.35%
- Packaging10mg
- Price$354
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3527AH | CathepsinSinhibitor | 10mg | $444 | 2021-12-16 | Buy |
| Ambeed | A473978 | LY3000328 98+% | 1mg | $42 | 2021-12-16 | Buy |
| Ambeed | A473978 | LY3000328 98+% | 5mg | $92 | 2021-12-16 | Buy |
| Ambeed | A473978 | LY3000328 98+% | 10mg | $135 | 2021-12-16 | Buy |
| Ambeed | A473978 | LY3000328 98+% | 25mg | $204 | 2021-12-16 | Buy |
| Ambeed | A473978 | LY3000328 98+% | 50mg | $304 | 2021-12-16 | Buy |
| Ambeed | A473978 | LY3000328 98+% | 100mg | $455 | 2021-12-16 | Buy |
| ApexBio Technology | A3284 | CathepsinSinhibitor | 5mg | $212 | 2021-12-16 | Buy |
| ApexBio Technology | A3284 | CathepsinSinhibitor | 10mM(in 1mL DMSO) | $250 | 2021-12-16 | Buy |
| ApexBio Technology | A3284 | CathepsinSinhibitor | 10mg | $275 | 2021-12-16 | Buy |
| Cayman Chemical | 29729 | LY3000328 | 500μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 29729 | LY3000328 | 1mg | $152 | 2024-03-01 | Buy |
| Cayman Chemical | 29729 | LY3000328 | 5mg | $356 | 2024-03-01 | Buy |
| Cayman Chemical | 29729 | LY3000328 | 10mg | $632 | 2024-03-01 | Buy |
| Chemenu | CM162803 | (3R,4S)-4-(4-fluorobenzamido)-6-(4-(oxetan-3-yl)piperazin-1-yl)chroman-3-ylmethylcarbamate 98% | 50mg | $628 | 2021-12-16 | Buy |
| ChemScene | CS-1120 | LY3000328 99.35% | 10mg | $354 | 2021-12-16 | Buy |
Properties
Boiling point :701.6±60.0 °C(Predicted)
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥24.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Powder
pka :12.50±0.46(Predicted)
color :White to off-white
InChIKey :NDEBZCZEAVMSQF-GOTSBHOMSA-N
SMILES :C(N[C@H]1C2=CC(N3CCN(C4COC4)CC3)=CC=C2OC[C@@H]1OC(NC)=O)(=O)C1=CC=C(F)C=C1
Density :1.38±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥24.25 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :Powder
pka :12.50±0.46(Predicted)
color :White to off-white
InChIKey :NDEBZCZEAVMSQF-GOTSBHOMSA-N
SMILES :C(N[C@H]1C2=CC(N3CCN(C4COC4)CC3)=CC=C2OC[C@@H]1OC(NC)=O)(=O)C1=CC=C(F)C=C1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
LY3000328 is a potent cathepsin S inhibitor (IC50 = 7.7 nM for the human enzyme). It is selective for cathepsin S over cathepsin L, K, B, and V (IC50s = >10,000, >10,000, 4,390, and 21,500 nM, respectively). LY3000328 (1-30 mg/kg) reduces aortic diameter in a mouse model of calcium chloride-induced abdominal aortic aneurysm.Suppliers and manufacturers
BOC Sciences
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Baoji Guokang Bio-Technology Co., Ltd.
HANGZHOU LEAP CHEM CO., LTD.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Amadis Chemical Company Limited
Shanghai Lollane Biological Technology Co.,Ltd.
Haoyuan Chemexpress Co., Ltd.
