Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> arglabin

arglabin

arglabin price.
  • $49 - $2200
  • Product name: arglabin
  • CAS: 84692-91-1
  • MF: C15H18O3
  • MW: 246.3
  • EINECS:
  • MDL Number:MFCD11519463
  • Synonyms:(3aR,4aS,6aS,9aS,9bR)-5,6,6a,7,9a,9b-Hexahydro-1,4a-dimethyl-7-methylene-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one;arglabin;(3aR,4aS)-1,4aα-Dimethyl-7-methylene-4a,5,6,6aα,9aβ,9bα-hexahydro-3H-oxireno[8,8a]azuleno[4,5-b]furan-8(7H)-one;(3aS)-2,3,3aβ,4,5β,6,6a,7,9aβ,9bα-Decahydro-6α,6aα-epoxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2-one;3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one, 5,6,6a,7,9a,9b-hexahydro-1,4a-diMethyl-7-Methylene-, [4aS-(3aS*,4aα,6aα,9aβ,9bα)]-;Arglabine;3H-Oxireno[8,8a]azuleno[4,5-b]furan-8(4aH)-one,5,6,6a,7,9a,9b-hexahydro-1,4a-dimethyl-7-methylene-, (3aR,4aS,6aS,9aS,9bR);Arglabin 84692-91-1
19 prices
Selected condition:
Brand
  • Adipogen Life Sciences
  • Arctom
  • Cayman Chemical
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
Package
  • 500μg
  • 1mg
  • 2.5mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CN2-0458-M005
  • Product descriptionArglabin ≥98%(HPLC)
  • Packaging5mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN89201
  • Product descriptionArglabin
  • Packaging5mg
  • Price$318
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number19502
  • Product descriptionArglabin
  • Packaging500μg
  • Price$49
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19502
  • Product descriptionArglabin
  • Packaging1mg
  • Price$92
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number19502
  • Product descriptionArglabin
  • Packaging5mg
  • Price$380
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3012
  • Product descriptionArglabin 99.17%
  • Packaging5mg
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3012
  • Product descriptionArglabin 99.17%
  • Packaging10mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3012
  • Product descriptionArglabin 99.17%
  • Packaging25mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3012
  • Product descriptionArglabin 99.17%
  • Packaging50mg
  • Price$800
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3012
  • Product descriptionArglabin 99.17%
  • Packaging100mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32000274
  • Product descriptionArglabin 98+%
  • Packaging5mg
  • Price$228
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32000274
  • Product descriptionArglabin 98+%
  • Packaging10mg
  • Price$326
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32000274
  • Product descriptionArglabin 98+%
  • Packaging50mg
  • Price$977
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD32000274
  • Product descriptionArglabin 98+%
  • Packaging100mg
  • Price$1367
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC9645
  • Product description(+)-Arglabin >98%
  • Packaging100mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number63004
  • Product descriptionArglabin
  • Packaging25mg
  • Price$2200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences AG-CN2-0458-M005 Arglabin ≥98%(HPLC) 5mg $300 2021-12-16 Buy
Arctom CFN89201 Arglabin 5mg $318 2021-12-16 Buy
Cayman Chemical 19502 Arglabin 500μg $49 2024-03-01 Buy
Cayman Chemical 19502 Arglabin 1mg $92 2024-03-01 Buy
Cayman Chemical 19502 Arglabin 5mg $380 2024-03-01 Buy
ChemScene CS-3012 Arglabin 99.17% 5mg $280 2021-12-16 Buy
ChemScene CS-3012 Arglabin 99.17% 10mg $450 2021-12-16 Buy
ChemScene CS-3012 Arglabin 99.17% 25mg $600 2021-12-16 Buy
ChemScene CS-3012 Arglabin 99.17% 50mg $800 2021-12-16 Buy
ChemScene CS-3012 Arglabin 99.17% 100mg $1200 2021-12-16 Buy
Crysdot CD32000274 Arglabin 98+% 5mg $228 2021-12-16 Buy
Crysdot CD32000274 Arglabin 98+% 10mg $326 2021-12-16 Buy
Crysdot CD32000274 Arglabin 98+% 50mg $977 2021-12-16 Buy
Crysdot CD32000274 Arglabin 98+% 100mg $1367 2021-12-16 Buy
DC Chemicals DC9645 (+)-Arglabin >98% 100mg $1200 2021-12-16 Buy
Medical Isotopes, Inc. 63004 Arglabin 25mg $2200 2021-12-16 Buy

Properties

Melting point :100-102 °C
Boiling point :404.6±45.0 °C(Predicted)
Density :1.22±0.1 g/cm3(Predicted)
storage temp. :Amber Vial, -20°C Freezer, Under inert atmosphere
solubility :Chloroform (Slightly)
form :Solid
color :Off-White

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

Arglabin is a new antineoplastic agent launched in Russia for the treatment of a variety of cancers. It is a sesquiterpene gamma-lactone extracted from Artemisia glabella, a plant from Kazakstan; it was first developed in Kazakstan followed by US and other countries as an ethical pharmaceutical. Arglabin can be obtained by resin extraction from A.glabella, purification by chromatography and finally recrystallization. Arglabin is a potent and selective inhibitor of farnesyl transferase, an enzyme critical to the function of the Ras oncogene in cancer cell reproduction. It showed a strong Inhibitory effect against tumor cells proliferation in in vitro models of transformed mouse hepatocytes and splenocytes. This cytotoxic effect against tumor cells was 50-100 times higher than that on intact cells. In many patients with various cancers, Arglabin was shown to stop or inhibit the tumour development, alone or in combination with other anticancer agents, and was reportedly well tolerated with few sideeffects. Promising response rates were also reported with Arglabin after treating other 《difficult-to-treat cancers》 such as breast, ovarian, lung or colon cancers.

Related product price