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ChemicalBook >> CAS DataBase List >> isatidine

isatidine

isatidine price.
  • $259.6 - $2654
  • Product name: isatidine
  • CAS: 15503-86-3
  • MF: C18H25NO7
  • MW: 367.39
  • EINECS:
  • MDL Number:MFCD00074872
  • Synonyms:isatidine;RETRORSINE-N-OXIDE;12,18-Dihydroxy-11,16-dioxosenecionane 4-oxide;12,18-Dihydroxysenecionane-11,16-dione 4-oxide;Retrorsin-N-oxid;[1,6]Dioxacyclododecino[2,3,4-gh]pyrrolizine-2,7-dione, 3-ethylidene-3,4,5,6,9,11,13,14,14a,14b-decahydro-6-hydroxy-6-(hydroxymethyl)-5-methyl-, 12-oxide, (3Z,5R,6S,14aR,14bR)-;Retrorsine-N-oxide 100 μg/mL in Water;Retrorsine N-oxide (Standard)
19 prices
Selected condition:
Brand
  • aablocks
  • ACHEMBLOCK
  • Arctom
  • Biosynth
  • ChemScene
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 2mg
  • 2.5mg
  • 5MG
  • 10mg
  • 25MG
  • 100MG
  • Manufactureraablocks
  • Product numberAA001NHI
  • Product descriptionRetrorsine N-oxide HPLC≥97%
  • Packaging10mg
  • Price$1240
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX212281
  • Product descriptionIsatidine 97%
  • Packaging100MG
  • Price$2380
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX212281
  • Product descriptionIsatidine 97%
  • Packaging25MG
  • Price$915
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberX212281
  • Product descriptionIsatidine 97%
  • Packaging5MG
  • Price$305
  • Updated2026-05-27
  • Buy
  • ManufacturerArctom
  • Product numberCFN00408
  • Product descriptionIsatidine ≥98%
  • Packaging5mg
  • Price$468
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFR161591
  • Product descriptionRetrorsine N-oxide
  • Packaging5mg
  • Price$584.1
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFR161591
  • Product descriptionRetrorsine N-oxide
  • Packaging1mg
  • Price$259.6
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFR161591
  • Product descriptionRetrorsine N-oxide
  • Packaging2mg
  • Price$389.4
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFR161591
  • Product descriptionRetrorsine N-oxide
  • Packaging10mg
  • Price$908.6
  • Updated2026-06-04
  • Buy
  • ManufacturerBiosynth
  • Product numberFR161591
  • Product descriptionRetrorsine N-oxide
  • Packaging25mg
  • Price$1963.25
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066628
  • Product descriptionRetrorsine N-oxide
  • Packaging1mg
  • Price$347
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066628
  • Product descriptionRetrorsine N-oxide
  • Packaging1mg
  • Price$347
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066628
  • Product descriptionRetrorsine N-oxide
  • Packaging5mg
  • Price$850
  • Updated2026-06-04
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0066628
  • Product descriptionRetrorsine N-oxide
  • Packaging5mg
  • Price$850
  • Updated2026-06-04
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number48572
  • Product descriptionRetrorsineN-Oxide
  • Packaging25mg
  • Price$2200
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberPHL82630
  • Product descriptionRetrorsine N-oxide phyproof? Reference Substance
  • Packaging10MG
  • Price$490
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA001NHI Retrorsine N-oxide HPLC≥97% 10mg $1240 2026-05-28 Buy
ACHEMBLOCK X212281 Isatidine 97% 100MG $2380 2026-05-27 Buy
ACHEMBLOCK X212281 Isatidine 97% 25MG $915 2026-05-27 Buy
ACHEMBLOCK X212281 Isatidine 97% 5MG $305 2026-05-27 Buy
Arctom CFN00408 Isatidine ≥98% 5mg $468 2021-12-16 Buy
Biosynth FR161591 Retrorsine N-oxide 5mg $584.1 2026-06-04 Buy
Biosynth FR161591 Retrorsine N-oxide 1mg $259.6 2026-06-04 Buy
Biosynth FR161591 Retrorsine N-oxide 2mg $389.4 2026-06-04 Buy
Biosynth FR161591 Retrorsine N-oxide 10mg $908.6 2026-06-04 Buy
Biosynth FR161591 Retrorsine N-oxide 25mg $1963.25 2026-06-04 Buy
ChemScene CS-0066628 Retrorsine N-oxide 1mg $347 2026-06-04 Buy
ChemScene CS-0066628 Retrorsine N-oxide 1mg $347 2026-06-04 Buy
ChemScene CS-0066628 Retrorsine N-oxide 5mg $850 2026-06-04 Buy
ChemScene CS-0066628 Retrorsine N-oxide 5mg $850 2026-06-04 Buy
Medical Isotopes, Inc. 48572 RetrorsineN-Oxide 25mg $2200 2021-12-16 Buy
Sigma-Aldrich PHL82630 Retrorsine N-oxide phyproof? Reference Substance 10MG $490 2026-04-30 Buy

Properties

Melting point :145°C
Boiling point :497.95°C (rough estimate)
Density :1.3204 (rough estimate)
refractive index :1.5100 (estimate)
pka :11.96±0.40(Predicted)
IARC :3 (Vol. 10, Sup 7) 1987
EPA Substance Registry System :Isatidine (15503-86-3)

Safety Information

Symbol(GHS): Health Hazard (GHS08)Skull and Crossbones (GHS06)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H300 Fatal if swallowed Acute toxicity,oral Category 1, 2 Danger P264, P270, P301+P310, P321, P330,P405, P501
H373 May cause damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 2 Warning P260, P314, P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P314 Get medical advice/attention if you feel unwell.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

This hepatotoxic alkaloid occurs in certain Senecio species and was first isolated from S. isatideus D.C. It occurs abundantly in S. retrorsus D.C. and S. scleratus Schw. The alkaloid crystallizes in rhombic prisms as the dihydrate and has [α]27D . 8.25° (H 20). It is soluble in MeOH, hot EtOH and hot H20 but virtually insoluble in Et 20, Me2CO or CHCl 3. On reduction it absorbs 4 molecules of H2 to give hexahydrodeoxyisatidine which melts at l15-l20°C and then remelts at l83-4°C following an intermediate solidification. This compound gives a hydrochloride, m.p. 218°C (dec.); [α]20D - 52.5° (H20) and may be hydrolyzed with Ba(OHh to give a basic product, tetrahydroisatinecine, CSH1703N, m.p. l74.5°C; [α]20D - 88° (H 20). The alkaloid itself, on hydrolysis with Ba(OHh yields isatinecine and two acid products, isatinecic acid and the monolactone, the latter almost certainly being formed by the action of the base upon the acid.

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