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ChemicalBook >> CAS DataBase List >> lurasidone

lurasidone

lurasidone price.
  • $39 - $2245.7
  • Product name: lurasidone
  • CAS: 367514-87-2
  • MF: C28H36N4O2S
  • MW: 492.68
  • EINECS:696-042-8
  • MDL Number:MFCD14635357
  • Synonyms:4-{[(1R,2R)-2-{[4-(2$l^{4}-thia-6-azatricyclo[5.4.0.0^{2,6}]undeca-1(11),2,4,7,9-pentaen-5-yl)piperazin-1-yl]Methyl}cyclohexyl]Methyl}-4-azatricyclo[5.2.1.0^{2,6}]deca-1(9),2(6),7-triene-3,5-dione;lurasidone;(3aR,4S,7R,7aS)-2-[[(1R,2R)-2-[[4-(1,2-Benzisothiazol-3-yl)-1-piperazinyl]methyl]cyclohexyl]methyl]hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione;Lurasidone (SM13496);(3aR,4S,7R,7aS)-2-{[(1R,2R)-2-{[4-(1,2-benzothiazol-3-yl)piperazin-1-yl]Methyl}cyclohexyl]Methyl}hexahydro-1H-4,7-Methanoisoindole-1,3(2H)-dione;urasidone;Lurasidone, >=98%;Lurasidone Base
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  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • Arctom
  • AvaChem
  • Biorbyt Ltd
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  • ChemScene
  • Chemtos
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  • Manufactureraablocks
  • Product numberAA003781
  • Product description(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95
  • Packaging5mg
  • Price$52
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003781
  • Product description(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95
  • Packaging10mg
  • Price$63
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003781
  • Product description(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95%
  • Packaging250mg
  • Price$74
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003781
  • Product description(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95%
  • Packaging1g
  • Price$174
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003781
  • Product description(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95%
  • Packaging5g
  • Price$507
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003781
  • Product description(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95%
  • Packaging10g
  • Price$874
  • Updated2026-05-28
  • Buy
  • Manufactureraablocks
  • Product numberAA003781
  • Product description(3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95%
  • Packaging25g
  • Price$1742
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberA-581
  • Product descriptionLurasidone 98%
  • Packaging1G
  • Price$125
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberA-581
  • Product descriptionLurasidone 98%
  • Packaging5G
  • Price$350
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberA-581
  • Product descriptionLurasidone 98%
  • Packaging100MG
  • Price$40
  • Updated2026-05-27
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  • ManufacturerAK Scientific
  • Product numberY0344
  • Product descriptionLurasidone
  • Packaging10mg
  • Price$97
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ55517
  • Product descriptionLurasidone
  • Packaging50mg
  • Price$120
  • Updated2021-12-16
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  • ManufacturerAK Scientific
  • Product numberJ55517
  • Product descriptionLurasidone
  • Packaging100mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013701
  • Product description(3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00%
  • Packaging5MG
  • Price$497.35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0013701
  • Product description(3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00%
  • Packaging0.025G
  • Price$783
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberHY-B0032AR
  • Product descriptionLurasidone (Standard) 98%
  • Packaging100mg
  • Price$559
  • Updated2026-05-26
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003781 (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95 5mg $52 2026-05-28 Buy
aablocks AA003781 (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95 10mg $63 2026-05-28 Buy
aablocks AA003781 (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95% 250mg $74 2026-05-28 Buy
aablocks AA003781 (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95% 1g $174 2026-05-28 Buy
aablocks AA003781 (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95% 5g $507 2026-05-28 Buy
aablocks AA003781 (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95% 10g $874 2026-05-28 Buy
aablocks AA003781 (3aR,4S,7R,7aS)-2-((1R,2R)-2-(4-(1,2-Benzothiazol-3-yl)piperazin-1-ylmethyl)cyclohexylmethyl)hexahydro-4,7-methano-2H-isoindole-1,3-dione 95% 25g $1742 2026-05-28 Buy
ACHEMBLOCK A-581 Lurasidone 98% 1G $125 2026-05-27 Buy
ACHEMBLOCK A-581 Lurasidone 98% 5G $350 2026-05-27 Buy
ACHEMBLOCK A-581 Lurasidone 98% 100MG $40 2026-05-27 Buy
AK Scientific Y0344 Lurasidone 10mg $97 2021-12-16 Buy
AK Scientific J55517 Lurasidone 50mg $120 2021-12-16 Buy
AK Scientific J55517 Lurasidone 100mg $180 2021-12-16 Buy
American Custom Chemicals Corporation API0013701 (3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00% 5MG $497.35 2021-12-16 Buy
American Custom Chemicals Corporation API0013701 (3AR,4S,7R,7AS)-2-[((1R,2R)-2-[[4-(1,2-BENZISOTHIAZOL-3-YL)-PIPERAZIN-1-YL]METHYL]CYCLOHEXYL)METHYL]HEXAHYDRO-1H-4,7-METHANISOINDOL-1,3-DIONE 95.00% 0.025G $783 2021-12-16 Buy
Arctom HY-B0032AR Lurasidone (Standard) 98% 100mg $559 2026-05-26 Buy

Properties

Melting point :146-149°C
Boiling point :623.4±55.0 °C(Predicted)
Density :1.273
storage temp. :-20°C Freezer
solubility :Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
pka :8.41±0.50(Predicted)
form :Solid
color :White to Off-White
InChIKey :PQXKDMSYBGKCJA-CVTJIBDQSA-N
SMILES :C1(=O)[C@]2([H])[C@@]([H])([C@]3([H])C[C@@]2([H])CC3)C(=O)N1C[C@@H]1CCCC[C@H]1CN1CCN(C2C3=C(SN=2)C=CC=C3)CC1
CAS DataBase Reference :367514-87-2

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
Precautionary statements:
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The atypical antipsychotic lurasidone (also known as SM-13496) was approved in the United States in 2010 as an oral agent for the treatment of patients with schizophrenia. Lurasidone has potent affinity for D2 (Ki= 1.7 nM) and 5-HT2A (Ki= 2.0 nM) receptors and acts as an antagonist at both receptors. It is also a partial agonist at the 5-HT1A receptor and, unlike other atypical agents, is a potent antagonist at the 5-HT7 receptor; both of these activities are thought to confer beneficial cognitive properties. Lurasidone is further differentiated by its lack of affinity for muscarinic and histamine H1 receptors and its weak affinity for the 5-HT2C receptor. Antagonism at H1 and 5-HT2C receptors has been implicated in weight gain associated with atypical agents, while muscarinic receptor antagonism is associated with cognitive deficits.

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