neplanocin A
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- $270 - $2096
- Product name: neplanocin A
- CAS: 72877-50-0
- MF: C11H13N5O3
- MW: 263.25
- EINECS:
- MDL Number:MFCD01735607
- Synonyms:neplanocin A;A-11079B16;Antibiotic A-11079B16;Neoplanocin A;3-Neplanocin A;()-Neplanocin A Exclusive;3-Cyclopentene-1,2-diol, 5-(6-amino-9H-purin-9-yl)-3-(hydroxymethyl)-, (1S,2R,5R)-;(?)-Neplanocin A
4 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
Package
- 500μg
- 1mg
- 5mg
- ManufacturerAK Scientific
- Product number4504CA
- Product descriptionNeplanocinA
- Packaging1mg
- Price$667
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10584
- Product description(?)-Neplanocin A ≥98%
- Packaging500μg
- Price$270
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10584
- Product description(?)-Neplanocin A ≥98%
- Packaging1mg
- Price$510
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10584
- Product description(?)-Neplanocin A ≥98%
- Packaging5mg
- Price$2096
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 4504CA | NeplanocinA | 1mg | $667 | 2021-12-16 | Buy |
| Cayman Chemical | 10584 | (?)-Neplanocin A ≥98% | 500μg | $270 | 2024-03-01 | Buy |
| Cayman Chemical | 10584 | (?)-Neplanocin A ≥98% | 1mg | $510 | 2024-03-01 | Buy |
| Cayman Chemical | 10584 | (?)-Neplanocin A ≥98% | 5mg | $2096 | 2024-03-01 | Buy |
Properties
Melting point :214-216 °C (decomp)
Boiling point :632.6±65.0 °C(Predicted)
Density :1.91±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 0.2 mg/ml; DMSO: 3 mg/ml; PBS (pH 7.2): 0.3 mg/ml
form :A crystalline solid
pka :13.43±0.70(Predicted)
color :White to off-white
Boiling point :632.6±65.0 °C(Predicted)
Density :1.91±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 0.2 mg/ml; DMSO: 3 mg/ml; PBS (pH 7.2): 0.3 mg/ml
form :A crystalline solid
pka :13.43±0.70(Predicted)
color :White to off-white
Safety Information
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Description
S-Adenosylhomocysteine (SAH) hydrolase catalyzes the reversible hydrolysis of SAH to adenosine and homocysteine. The inhibition of SAH hydrolase causes the intracellular accumulation of SAH, elevating the ratio of SAH to S-adenosylmethionine (SAM) and inhibiting SAM-dependent methyltransferase. (?)-Neplanocin A potently and irreversibly inactivates SAH hydrolase (Ki = 8.39 nM). It has antitumor activity against mouse leukemia L1210 cells and broad-spectrum antiviral activity. Neplanocin A is more potent against vesicular stomatitis than the reversible SAH hydrolase inhibitor 3-deazaneplanocin (ID50 = 0.07 and 0.3 μg/ml, respectively).More related product prices
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