TIN PROTOPORPHYRIN IX DICHLORIDE
2物価
選択条件:
ブランド
- 富士フイルム和光純薬株式会社(wako)
パッケージ
- 10mg
- 50mg
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01TOC0747
- 製品説明
- 英語製品説明Tin protoporphyrin IX dichloride
- 包装単位10mg
- 価格¥31000
- 更新しました2021-03-23
- 購入
- 生産者富士フイルム和光純薬株式会社(wako)
- 製品番号W01TOC0747
- 製品説明
- 英語製品説明Tin protoporphyrin IX dichloride
- 包装単位50mg
- 価格¥126000
- 更新しました2021-03-23
- 購入
生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
---|---|---|---|---|---|---|
富士フイルム和光純薬株式会社(wako) | W01TOC0747 | Tin protoporphyrin IX dichloride |
10mg | ¥31000 | 2021-03-23 | 購入 |
富士フイルム和光純薬株式会社(wako) | W01TOC0747 | Tin protoporphyrin IX dichloride |
50mg | ¥126000 | 2021-03-23 | 購入 |
プロパティ
貯蔵温度 :Store at RT
溶解性 :Soluble to 25 mM in 1eq. NaOH and to 5 mM in DMSO
外見 :Dark red to violet solid.
溶解性 :Soluble to 25 mM in 1eq. NaOH and to 5 mM in DMSO
外見 :Dark red to violet solid.
安全情報
絵表示(GHS): | |||||||||||||||||||||||||||||
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注意喚起語: | Warning | ||||||||||||||||||||||||||||
危険有害性情報: |
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注意書き: |
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説明
Heme oxygenase (HO) converts protoheme to biliverdin, which in turn is enzymatically metabolized to bilirubin . While HO-2 is constitutively expressed, HO-1 can be induced by its heme substrate as well as by heavy metals, oxidizing agents, and other environmental stresses. Tin protoporphyrin IX (SnPPIX) is a synthetic heme analog that selectively inhibits HO-1 (Ki = 11 nM) over HO-2 (IC50 = 7.5 μM). It also weakly inhibits endothelial nitric oxide synthase and soluble guanylyl cyclase (IC50s = 35 and 30 nM, respectively). SnPPIX prevents hyperbilirubinemia in neonates by blocking HO-1 activity that increases postnatally. It is rapidly cleared from plasma and persists in certain tissues, including kidney, liver, and spleen. SnPPIX is commonly used as a tool to study the role of HO-1 activity in cells and in animals.関連商品価格
- プロトポルフィリン
¥29800-114800 - プロトポルフィリンIX亜鉛
¥13300-211300 - TIN PROTOPORPHYRIN IX DICHLORIDE
¥31000-126000
供給者とメーカー
CONIER CHEM AND PHARMA LIMITED
Chengdu Aslee Biopharmaceuticals, Inc.
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Shanghai Acmec Biochemical Technology Co., Ltd.
Aladdin Scientific
J & K SCIENTIFIC LTD.
3B Pharmachem (Wuhan) International Co.,Ltd.
ShangHai Caerulum Pharma Discovery Co., Ltd.
Chengdu Aslee Biopharmaceuticals, Inc