| | 57-64-7 Basic information More.. |
| Product Name: | PHYSOSTIGMINE SALICYLATE | | Synonyms: | PHYSOSTIGMINE SALICYLATE SALT;2-hydroxy-,compd.with(3as-cis)-1,2,3,3a,8,8a-hexahydro-1,3a,8-benzoicaci;ar-44;ESERINE MONOSALICYLATE;ESERINE SALICYLATE SALT;ESERINE SALICYLATE 99.9%;Physostigmine monosalicylate;Physostigmine salicylate (Eserine salicylate) | | CAS: | 57-64-7 | | MF: | C22H27N3O5 | | MW: | 413.47 | | EINECS: | 200-343-8 | | Mol File: | 57-64-7.mol |  |
Use
The salicylate ofphysostigmine (eserine salicylate) may be prepared byneutralizing an ethereal solution of the alkaloid with anethereal solution of salicylic acid. Excess salicylic acid isremoved from the precipitated product by washing itwith ether. The salicylate is less deliquescent than thesulfate.Physostigmine salicylate occurs as a white, shining,odorless crystal or white powder that is soluble in water(1:75), alcohol (1:16), or chloroform (1:6) but much lesssoluble in ether (1:250). On prolonged exposure to air andlight, the crystals turn red. The red may be removed bywashing the crystals with alcohol, although this causes lossof the compound as well. Aqueous solutions are neutral orslightly acidic and take on a red coloration after a period.The coloration may be taken as an index of the loss of activityof physostigmine solutions.
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57-64-7
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