163521-12-8 Basic information More..
Product Name:VILAZODONE
Synonyms:2-BenzofurancarboxaMide,5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]-1-piperazinyl]-;Vilazodonei;Vilazodone 5-[4-[4-(5-Cyanoindol-3-yl)butyl]piperazin-1-yl]benzofuran-2-carboxamide;5-(4-(4-(5-Cyano-1H-indol-3-yl)butyl)piperazin-1-yl)benzofuran-2-carboxamide;5-[4-[4-(5-cyano-1H-indol-3-yl)butyl]piperazin-1-yl]-1-benzofuran-2-carboxamide;Vilazodone, >=98%;Vilozodone;Vilazodone [inn]
CAS:163521-12-8
MF:C26H27N5O2
MW:441.52
EINECS:1308068-626-2
Mol File:163521-12-8.mol
163521-12-8

Use

Vilazodone is a kind of serotonergic antidepressant developed by Merck KGaA Company. It is a novel compound with high affinity and selectivity for the 5-hydroxytrptamine (5-HT) transporter and 5-HT (1A) receptors. It is indicated for the treatment of major depressive disorder (MDD). It is can be used as an alternative drugs for other kind of antidepressant classes drugs that cant be tolerated by patients. As a selective serotonin reuptake inhibitor, vilazodone can prevent the serotonin from re-entering into cell bodies, therefore making it remain longer inside the synapse. Moreover, it has a high selectivity for the serotonin-1A receptor, taking effect as a partial agonist that can simulate the production of serotonin. These effects result in increased serotonin in the synaptic cleft. This effect is related to the antidepressant effect of vilazodone in vivo.

VILAZODONE manufacturers

  • Vilazodone
  • US $48.00-40.00 / KG
  • 2023-05-04
  • CAS:163521-12-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 2tons
  • VILAZODONE USP/EP/BP
  • US $1.10 / g
  • 2021-07-27
  • CAS:163521-12-8
  • Min. Order: 1g
  • Purity: 99.9%
  • Supply Ability: 100 Tons min
  • vilazodone
  • US $15.00-10.00 / KG
  • 2021-07-13
  • CAS:163521-12-8
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
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