| | 81093-37-0 Basic information More.. |
| Product Name: | Pravastatin | | Synonyms: | KOPOSTAT;PRAVASTATIN;PRAVASELECT;ELISOR;EPTASTATIN SODIUM;(BETA R,DELTA R,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8-[(2S)-2-METHYL-1-OXOBUTOXY]-1-NAPHTHALENEHEPTANOIC ACID MONOSODIUM SALT;(BETAR, DELTAR,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA, DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHEPTANOIC ACID SODIUM;(BETA-R,DELTA-R,1S,2S,6S,8S,8AR)-1,2,6,7,8,8A-HEXAHYDRO-BETA,DELTA,6-TRIHYDROXY-2-METHYL-8[(2S)-2-METHYL-1-OXOBUTOXYL]-1-NAPHTHALENEHEPTANOIC ACID NA | | CAS: | 81093-37-0 | | MF: | C23H36O7 | | MW: | 424.53 | | EINECS: | | | Mol File: | 81093-37-0.mol |  |
Use
Pravastatin, sodium 1,2,6,7,8,8a-hexahydro-β,δ,6-trihydroxy-2-methyl-8-(2-methyl-1-oxobutoxy)-1-naphthaleneheptanoate (Pravachol), is the most rapid actingof the three HMG-CoA reductase inhibitor drugs, reachinga peak concentration in about 1 hour. The sodium salt of theβ-hydroxy acid is more hydrophilic than the lactone forms ofthe other two agents, which may explain this property. In addition,the open form of the lactone ring contributes to a morehydrophilic agent, which, in turn, results in less CNS penetration.This explains, in part, why pravastatin has fewer CNSside effects than the more lipophilic lactone ester of this classof agents. Absorption of pravastatin following oral administrationcan be inhibited by resins such as cholestyramine becauseof the presence of the carboxylic acid function on thedrug. The lactone forms of lovastatin and simvastatin are lessaffected by cholestyramine.
- Pravastatin USP/EP/BP
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- US $1.10 / g
- 2021-08-06
- CAS:81093-37-0
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons min
- Pravastatin
-
- US $15.00-10.00 / KG
- 2021-07-13
- CAS:81093-37-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
- Pravastatin
-
- US $15.00-10.00 / KG
- 2021-07-10
- CAS:81093-37-0
- Min. Order: 1KG
- Purity: 99%+ HPLC
- Supply Ability: Monthly supply of 1 ton
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81093-37-0
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| Company Name: |
Amadis Chemical Company Limited
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China |
| Products Intro: |
Product Name:(3R,5R)-3,5-dihydroxy-7-[(1S,2S,6S,8S)-6-hydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]heptanoic acid
CAS:81093-37-0
Purity:0.97 Package:mgs,gs,kgs Remarks:A840039 |
| CB Index: |
58 |
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