897383-62-9 Basic information More..
Product Name:AST-1306
Synonyms:AST-1306;ALS 1306;N-[4-[[3-Chloro-4-[(3-fluorobenzyl)oxy]phenyl]amino]quinazolin-6-yl]acrylamide;N-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-propenamide;Allitinib (AST1306);Allitinib;CS-590;N-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)acrylamide
CAS:897383-62-9
MF:C24H18ClFN4O2
MW:448.88
EINECS:
Mol File:897383-62-9.mol
897383-62-9

Use

AST-1306 is a selective irreversible inhibitor of the epidermal growth factor receptor (EGFR) 1 and 2. Studies show that AST-1306 inhibited the enzymatic activities of wild-type EGF) and ErbB2 as well as EGFR resistant mutant in both cell-free and cell-based systems. AST-1306 was more effective in inhibiting tumors with ErbB2-overexpressing cells than EGFR-overexpressing tumor.

AST-1306 manufacturers

  • Allitinib
  • US $48.00-185.00 / mg
  • 2025-11-10
  • CAS:897383-62-9
  • Min. Order:
  • Purity: 99.10%
  • Supply Ability: 10g
  • Allitinib
  • US $48.00-185.00 / mg
  • 2025-11-10
  • CAS:897383-62-9
  • Min. Order:
  • Purity: 99.10%
  • Supply Ability: 10g
  • AST-1306
  • US $9.80 / KG
  • 2020-01-13
  • CAS:897383-62-9
  • Min. Order: 1g
  • Purity: ≥99%
  • Supply Ability: 100kg
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