| | 331771-20-1 Basic information More.. |
| Product Name: | ZM 447439 | | Synonyms: | N-[4-[[6-METHOXY-7-[3-(4-MORPHOLINYL)PROPOXY]-4-QUINAZOLINYL]AMINO]PHENYL]BENZAMIDE;ZM 447439;N-(4-((6-Methoxy-7-(3-Morpholinopropoxy)quinazolin-4-yl)aMino)phenyl)benzaMide;BenzaMide, N-[4-[[6-Methoxy-7-[3-(4-Morpholinyl)propoxy]-4-quinazolinyl]aMino]phenyl]-;ZM-447439;ZM447439;ZM 447439, >=98%;Aurora Kinase Inhibitor VI, ZM447439 - CAS 331771-20-1 - Calbiochem;CS-77 | | CAS: | 331771-20-1 | | MF: | C29H31N5O4 | | MW: | 513.59 | | EINECS: | | | Mol File: | 331771-20-1.mol |  |
Use
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
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331771-20-1
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