| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HOE 689
CAS:33156-28-4
Package:10mg;50mg
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| Company Name: |
Leancare Ltd.
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| Tel: |
+33 962096793 |
| Email: |
enquiry@leancare.co.uk |
| Products Intro: |
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| Company Name: |
2A PharmaChem USA
|
| Tel: |
(630) 737-0988 |
| Email: |
sales@2apharmachem.com |
| Products Intro: |
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| | Ramnodigin Basic information |
| Product Name: | Ramnodigin | | Synonyms: | Ramnodigin;14-Hydroxy-3beta-((2,3,6-trihydroxy-alpha-L-erythro-hexopyranosyl)oxy)-5beta-card-20(22)-enolide;Ramnodigin [inn];Ramnodiginum;Unii-Z8sry7br30;Card-20(22)-enolide, 14-hydroxy-3-[[(2R,5R,6S)-tetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]oxy]-, (3β,5β)-;HOE 689 | | CAS: | 33156-28-4 | | MF: | C29H44O6 | | MW: | 488.661 | | EINECS: | | | Product Categories: | | | Mol File: | 33156-28-4.mol |  |
| | Ramnodigin Chemical Properties |
| Melting point | 172-173 °C | | Boiling point | 646.6±55.0 °C(Predicted) | | density | 1.22±0.1 g/cm3(Predicted) | | pka | 14.19±0.60(Predicted) |
| | Ramnodigin Usage And Synthesis |
| Uses | HOE 689 (Ramnodigin) is an analog of Digitoxin (HY-B1357). HOE 689 exhibits cytotoxicity to lung cancer cells and induces apoptosis in cancer cell NCI-H460 with an IC50 of 52 nM[1]. | | References | [1] Wang HY, et al., C5'-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity. ACS Med Chem Lett. 2011 Apr 14;2(4):259-263. DOI:10.1021/ml100291n |
| | Ramnodigin Preparation Products And Raw materials |
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