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Lynnchem
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86-(0)29-85992781 17792393971 |
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| Products Intro: |
Product Name:kijanimicin
CAS:78798-08-0
Purity:>99% by HPLC Package:1mg;5mg
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| | kijanimicin Basic information |
| Product Name: | kijanimicin | | Synonyms: | kijanimicin;Sch 25663;18H-16a,19-Metheno-16aH-benzo[b]naphth[2,1-j]oxacyclotetradecin-18,20(1H)-dione, 4-[(O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-O-[2,6-dideoxy-4-O-methyl-β-L-ribo-hexopyranosyl-(1→4)]-O-2,6-dideoxy-α-L-ribo-hexopyranosyl-(1→3)-2,6-dideoxy-α-L-ribo-hexopyranosyl)oxy]-2,3,4,4a,6a,9,10,12a,15,16,20a,20...;Kijanimicin sodium salt | | CAS: | 78798-08-0 | | MF: | C67H100N2O24 | | MW: | 1317.52 | | EINECS: | | | Product Categories: | | | Mol File: | 78798-08-0.mol |  |
| | kijanimicin Chemical Properties |
| density | 1.35±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble | | form | A solid | | pka | 4.50±1.00(Predicted) |
| | kijanimicin Usage And Synthesis |
| Uses | Kijanimicin is an antibacterial tetronic acid compound. | | Uses | Kijanimicin is a tetronic acid related to saccharocarcin, chlorothricin, versipelostatin and tetrocarcin. Like the tetrocarcins, kijanimicin contains an unusual nitroaminoglycoside. Kijanimicin is a potent antibacterial, antimalarial and antitumour active. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway. |
| | kijanimicin Preparation Products And Raw materials |
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