(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran

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(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran Basic information
Product Name:(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran
Synonyms:(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran;Strychnospermine;Ethanone, 1-[(4bR,7S,7aS,8aR,9S,10R,12aR,12bS)-5,6,8,8a,9,10,12a,12b-octahydro-2-methoxy-10-methyl-7aH-7,9-methanopyrano[3,4-a]pyrrolo[2,3-d]carbazol-13(12H)-yl]-
CAS:509-45-5
MF:C22H28N2O3
MW:368.47
EINECS:
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Mol File:509-45-5.mol
(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran Structure
(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran Chemical Properties
Melting point 208-9°C
Boiling point 585.318±50.00 °C(Press: 760.00 Torr)(predicted)
density 1.303±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka8.786±0.40(predicted)
form A solid
Safety Information
MSDS Information
(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran Usage And Synthesis
DescriptionA strychnine type alkaloid from Strychnos psilosperrna, the base yields clusters of colourless needles from aqueous MeOH. It is dextrorotatory with [α]D+ 58° (c 2.07, CHCI3). It yields crystalline salts and derivatives including the hydro_x0002_chloride, m.p. 330-2°C (dec.); picrate, m.p. 254°C (dec.) and the methiodide, m.p. 335°C (dec.). Oxidation with H20 2 gives the N-oxide as colourless needles from boiling H20, m.p. 261-3°C (dec.).
UsesStrychnospermine is an alkaloid that has been found in S. psilosperma.
ReferencesAnet, Hughes, Ritchie., Austral. J. Chern., 6,58 (1953)
Anet, Robinson., J. Chern. Soc., 2253 (I955)
Anet., Can. J. Chern., 41,883 (1963)
(19R)-1-Acetyl-17,19-epoxy-11-methoxycuran Preparation Products And Raw materials
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