| Company Name: |
J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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jkinfo@jkchemical.com |
| Products Intro: |
Product Name:3,5-Dichloro-4'-fluorobenzophenone
CAS:197439-66-0
Purity:97% Package:10g,1g,25g,2g,5g
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| Company Name: |
Hangzhou J&H Chemical Co., Ltd.
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| Tel: |
0571-87396432 |
| Email: |
sales@jhechem.com |
| Products Intro: |
Product Name:(3,5-dichlorophenyl)-(4-fluorophenyl)methanone
CAS:197439-66-0
Purity:98% HPLC Package:50KG;10KG;5KG;1KG
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| Company Name: |
Matrix Scientific
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| Tel: |
803 788-9494 All other calls |
| Email: |
sales@matrixscientific.com |
| Products Intro: |
Product Name:3,5-Dichloro-4'-fluorobenzophenone
CAS:197439-66-0
Purity:97%
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| | 3,5-DICHLORO-4'-FLUOROBENZOPHENONE Basic information |
| Product Name: | 3,5-DICHLORO-4'-FLUOROBENZOPHENONE | | Synonyms: | UKRORGSYN-BB BBV-5117241;3,5-DICHLORO-4'-FLUOROBENZOPHENONE;(3,5-Dichloro-phenyl)-(4-fluoro-phenyl)-methanone;Methanone, (3,5-dichlorophenyl)(4-fluorophenyl)- | | CAS: | 197439-66-0 | | MF: | C13H7Cl2FO | | MW: | 269.1 | | EINECS: | | | Product Categories: | | | Mol File: | 197439-66-0.mol |  |
| | 3,5-DICHLORO-4'-FLUOROBENZOPHENONE Chemical Properties |
| Melting point | 65-67 °C(Solv: ethanol (64-17-5)) | | Boiling point | 387.0±42.0 °C(Predicted) | | density | 1.375±0.06 g/cm3(Predicted) |
| | 3,5-DICHLORO-4'-FLUOROBENZOPHENONE Usage And Synthesis |
| Preparation | Synthesis of (3,5-Dichlorophenyl)-(4-fluorophenyl)methanone.
3,5-Dichlorobenzoic acid (12.5 g, 65 mmol) was heated at reflux with thionyl chloride for 4 h. After removal of the thionyl chloride, fluorobenzene (5.6 mL, 5.76 g, 60 mmol) and anhydrous aluminum chloride (8.53 g, 64 mmol) were added to the oily residue and the reaction mixture was stirred at 140 °C for 3 h. After cooling to 70 °C, it was poured under vigorous stirring onto ice-water (500 g). The crude product was filtered off, washed with water, and recrystallized from ethanol to give (3,5-Dichlorophenyl)-(4-fluorophenyl)methanone (11.9 g, 73.6 %) as colorless crystals.Mp. 65-67 °C (ethanol);
1 H NMR (CDCl3, 200 MHz, 25 °C): δ 7.85 (2H, dd, J = 8.8 Hz, 4 JHF = 5.5 Hz); 7.61 (2H, d, J = 1.8 Hz); 7.58 (1H, d, J = 1.8 Hz); 7.20 (2H, t, J = 8.8 Hz). IR (KBr): 1663, 1598 cm-1. Anal. Calcd for C13H7Cl2FO (269.10): C, 58.02; H, 2.62; Cl, 26.35. Found: C, 57.80; H, 2.60; Cl, 26.07 %. |
| | 3,5-DICHLORO-4'-FLUOROBENZOPHENONE Preparation Products And Raw materials |
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