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Product Name:1-Octadecyl lysophosphatidic acid
CAS:52977-29-4
Purity:95% Package:1G;10G;100G Remarks:1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of
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Product Name:1-Octadecyl Lysophosphatidic Acid
CAS:52977-29-4
Purity:>98% Package:1mg;10mg;50mg;100mg;
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Product Name:1-Octadecyl Lysophosphatidic Acid
CAS:52977-29-4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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Product Name:1-OCTADECYL LPA
CAS:52977-29-4
Purity:98% Package:5mg; 10mg; 500ug; 1mg Remarks:Medbio
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| | 1-OCTADECYL LPA Basic information |
| Product Name: | 1-OCTADECYL LPA | | Synonyms: | 1-OCTADECYL LPA;1-OCTADECYL LYSOPHOSPHATIDIC ACID;1-Octadecyl Lysophosphatidic Acid Exclusive;1,2-Propanediol, 3-(octadecyloxy)-, 1-(dihydrogen phosphate);1-Octadecyl Lysophosphatidic Acid (1-Octadecyl LPA) | | CAS: | 52977-29-4 | | MF: | C21H45O6P | | MW: | 424.55 | | EINECS: | | | Product Categories: | | | Mol File: | 52977-29-4.mol |  |
| | 1-OCTADECYL LPA Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; Ethanol: 10 mg/ml; Ethanol:PBS (pH 7.2) ((1:1): 0.5 mg/ml | | form | A crystalline solid |
| | 1-OCTADECYL LPA Usage And Synthesis |
| Description | 1-Octadecyl lysophosphatidic acid (1-octadecyl LPA) is a LPA analog containing stearic acid at the sn-1 position. LPA binds to one of five different G protein linked receptors to mediate a variety of biological responses including cell proliferation, smooth muscle contraction, platelet aggregation, neurite retraction, and cell motility.1,2 Alkyl ether-linked LPA derivatives have a higher platelet aggregating activity than the acyl derivatives, most likely stemming from an alkyl-specific LPA receptor. For example, 1-octadecyl LPA has a platelet aggregating EC50 value of 9 nM versus 1-octadecanoyl LPA which has an EC50 value of 177 nM.3 | | References | 1. Noguchi, K., Ishii, S., and Shimizu, T. Identification of p2y9/GPR23 as a novel G protein-coupled receptor for lysophosphatidic acid, structurally distant from the Edg family J. Biol. Chem. 278(28),25600-25606(2003).
2. Moolenaar, W.H. LPA: A novel lipid mediator with diverse biological actions Trends Cell Biol. 4(6),213-219(1994).
3. Tokumura, A., Sinomiya, J., Kishimoto, S., et al. Human platelets respond differentially to lysophosphatidic acids having a highly unsaturated fatty acyl group and alkyl ether-linked lysophosphatidic acids Biochem. J. 365,617-628(2002). |
| | 1-OCTADECYL LPA Preparation Products And Raw materials |
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