|
|
| | Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Basic information |
| Product Name: | Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate | | Synonyms: | Methyl 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylate;Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-Methylthiazole-5-carboxylate;Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate;Febuxostat-54;Febuxostat Methyl Ester Impurity;Febuxostat Impurity 8/Febuxostat Methyl Ester/Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate;5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, methyl ester;2-(3-(ethoxycarbonyl)-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid | | CAS: | 923942-34-1 | | MF: | C17H18N2O3S | | MW: | 330.4 | | EINECS: | | | Product Categories: | | | Mol File: | 923942-34-1.mol |  |
| | Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Chemical Properties |
| Melting point | 157-159°C | | Boiling point | 486.8±55.0 °C(Predicted) | | density | 1.24 | | storage temp. | 2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 0.95±0.10(Predicted) | | form | Solid | | color | White |
| | Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Usage And Synthesis |
| Uses | Methyl 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methylthiazole-5-carboxylate is a 4-Methylthiazole-5-carboxylic Acid derivative as a potential inhibitor of mucin onco proteins for breast cancer therapy.Also, it is derived from Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor and used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout. |
| | Methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate Preparation Products And Raw materials |
|