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BOC Sciences |
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TC-MCH 7c manufacturers
- TC-MCH 7c
-
- $95.00
-
2026-07-14
- CAS:864756-35-4
- Purity: 99.54%
- Supply Ability: 10g
- TC-MCH 7c
-
- $95.00
-
2026-07-14
- CAS:864756-35-4
- Purity: 99.54%
- Supply Ability: 10g
|
| | TC-MCH 7c Basic information |
| Product Name: | TC-MCH 7c | | Synonyms: | TC-MCH 7c;4-[(4-Fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-2(1H)-pyridinone;4-(4-Fluoro-benzyloxy)-1-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-1H-pyridin-2-one;TCMCH 7c,TC MCH 7c;2(1H)-Pyridinone, 4-[(4-fluorophenyl)methoxy]-1-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-;TC-MCH 7c, 10 mM in DMSO | | CAS: | 864756-35-4 | | MF: | C24H25FN2O3 | | MW: | 408.47 | | EINECS: | | | Product Categories: | | | Mol File: | 864756-35-4.mol |  |
| | TC-MCH 7c Chemical Properties |
| Melting point | 124-126 °C | | Boiling point | 606.3±55.0 °C(Predicted) | | density | 1.27±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | solubility | Soluble to 100 mM in 1eq. HCl and to 50 mM in DMSO | | form | Powder | | pka | 9.60±0.20(Predicted) | | color | Light yellow to yellow |
| | TC-MCH 7c Usage And Synthesis |
| Uses | TC-MCH 7c is a potent melanin-concentrating hormone 1 receptor antagonist. | | in vivo | TC-MCH 7c (oral; 3-30 mg/kg; once-daily for 1.5 months) exhibits excellent body weight reduction in a dose-dependent manner in DIO mice model[1].
TC-MCH 7c (oral; 3-30 mg/kg) with 30 mg/kg has plasma concentrations of 5.1, 1.8, and 0.7 μM at 2, 15, and 24 hours, respectively[2].
| Animal Model: | C57BL/6J DIO mice[1] | | Dosage: | 3, 10 and 30 mg/kg | | Administration: | Oral; once-daily for 1.5 months | | Result: | Exhibited excellent body weight reduction in a dose-dependent manner.
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| Animal Model: | Diet-induced obesity mice[2] | | Dosage: | 3, 10 and 30 mg/kg (Pharmacokinetic Analysis) | | Administration: | Oral | | Result: | Plasma concentrations at 2, 15, and 24 hours were 5.1, 1.8, and 0.7 μM, respectively.
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| | storage | Store at RT |
| | TC-MCH 7c Preparation Products And Raw materials |
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