Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)- manufacturers
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| | Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)- Basic information |
| Product Name: | Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)- | | Synonyms: | Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)-;Cathepsin Inhibitor 2 | | CAS: | 1017931-53-1 | | MF: | C19H21F6N3O | | MW: | 421.3799592 | | EINECS: | | | Product Categories: | | | Mol File: | 1017931-53-1.mol | ![Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)- Structure](CAS/20180527/GIF/1017931-53-1.gif) |
| | Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)- Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | form | Solid | | color | White to off-white |
| | Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)- Usage And Synthesis |
| Description | Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor extracted from patent WO2009123623A1, has a Ki of <20 nM. Cathepsin Inhibitor 2 (Please refer to paragraph 0229 for detailed information) potently inhibits Cathepsin S, Cathepsin F, Cathepsin L, and Cathepsin B with Kis of <20 nM, 21-500 nM, 21-500 nM, and 21-500 nM, respectively[1]. | | Uses | Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor extracted from patent WO2009123623A1, has a Ki of <20 nM. | | References | [1]. LINK, John, O, et al. DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS. WO2009123623A1. |
| | Heptanamide, N-(1-cyanocyclopropyl)-4,4-difluoro-2-[[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]amino]-, (2S)- Preparation Products And Raw materials |
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