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| 融点 | 165-170 °C(lit.) | | 沸点 | 129.78°C (rough estimate) | | 比重(密度) | 1.0596 (rough estimate) | | 屈折率 | 1.5500 (estimate) | | 貯蔵温度 | Inert atmosphere,Room Temperature | | 酸解離定数(Pka) | pK1: 1.60(+1) (25°C) | | 外見 | Crystalline Powder, Crystals and/or Chunks | | 色 | White to cream | | 水溶解度 | 1 g/mL | | Sensitive | Hygroscopic | | Merck | 14,44 | | BRN | 3591762 | | InChIKey | WCQOBLXWLRDEQA-UHFFFAOYSA-N | | CAS データベース | 124-42-5(CAS DataBase Reference) | | EPAの化学物質情報 | Ethanimidamide, monohydrochloride (124-42-5) |
| | アセトアミジン塩酸塩 Usage And Synthesis |
| 外観 | 白色～うすい黄色, 結晶～結晶性粉末 | | 溶解性 | 水及びエタノールに溶け、アセトンに溶けない。水に可溶。メタノールに溶解。アセトン、エーテルに不溶。 | | 使用上の注意 | 潮解性あり。 | | 化学的特性 | WHITE FINE CRYSTALLINE POWDER | | 使用 | Acetamidine hydrochloride was used in the preparation of decarboxyectoine. It was also used in the synthesis of ethyl 4-(4-hydroxyphenyl)methylidene-2-methyl-5-oxo-1-imidazolacetate. | | 一般的な説明 | Acetamidine hydrochloride is an amidine salt and its conversion to 2,4,6-trimethyl-sym-triazine has been studied. | | 純化方法 | The hydrochlorde can be recrystallised from small volumes of EtOH. Alternatively it is dissolved in EtOH, filtered, Et2O is added; filter the crystalline salt off under N2 and dry it in a vacuum desiccator over H2SO4. The salt is deliquescent and should be stored in a tightly stoppered container. Its solubility in H2O is 10% at room temperature and it is soluble in Me2CO. The free base reacts strongly alkaline in H2O. It has max 224nm ( 4000) in H2O. The picrate has m 252o (sintering at ~245o). [Dox Org Synth Coll Vol I 5 1941, Davies & Parsons Chem Ind (London) 628 1958, Barnes et al. J Am Chem Soc 62 1286 1940 give m 177-178o, Beilstein 2 H 185, 2 I 85, 2 II 183, 2 III 416, 2 IV 428.] |
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