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| | 3,4',5-トリメトキシ-trans-スチルベン 製品概要 |
| 化学名: | 3,4',5-トリメトキシ-trans-スチルベン | | 英語化学名: | 3,4',5-TRIMETHOXY-TRANS-STILBENE | | 别名: | 3,4',5-TRIMETHOXY-TRANS-STILBENE;(E)-1,3-Dimethoxy-5-(4-methoxystyryl)benzene;(E)-3,4',5-Trimethoxystilbene;3,5,4'-Trimethoxy-trans-stilbene;Trimethoxystilbene;3,4,5-TRIMETHOXY-TRANS-STILBENE 95+%;TRANS-1-(3,5-DIMETHOXYPHENYL)-2-(4-METHOXYPHENYL)ETHYLENE;TRISMETHOXY RESVERATROL | | CAS番号: | 22255-22-7 | | 分子式: | C17H18O3 | | 分子量: | 270.32 | | EINECS: | 694-659-7 | | カテゴリ情報: | Resveratrol;Intermediates & Fine Chemicals;Pharmaceuticals;Stilbenes | | Mol File: | 22255-22-7.mol |  |
| | 3,4',5-トリメトキシ-trans-スチルベン 物理性質 |
| 融点 | 57°C | | 沸点 | 423.8±35.0 °C(Predicted) | | 比重(密度) | 1.104±0.06 g/cm3(Predicted) | | 貯蔵温度 | Sealed in dry,2-8°C | | 溶解性 | DMSO: ≥34mg/mL | | 外見 | powder to crystal | | 色 | white to tan | | CAS データベース | 22255-22-7 |
| | 3,4',5-トリメトキシ-trans-スチルベン Usage And Synthesis |
| 外観 | 白色～うすい黄色粉末～結晶 | | 説明 | trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively). trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM. | | 化学的特性 | Pale Yellow Oil | | 使用 | Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. When the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers, the inhibition of cell growth and pro-apoptotic activities of resveratrol are enhanced. | | 使用 | A resveratrol analog with a variety of pharmacology action, including
inst microtubule-destabilization | | 使用 | A resveratrol analog with a variety of pharmacology action, including anti-cancer properties, anti-allergic activity, estrogenic activity, antiangiogenic activity, and vascular-targeting activity against microtubule-destabilization |
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