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| | 1,4-Di(2,2,2-trifluoroethoxy)benzene Basic information |
| Product Name: | 1,4-Di(2,2,2-trifluoroethoxy)benzene | | Synonyms: | 1,4-Bis(2,2,2-trifluoroethoxy)benzene 97%;1,4-Bis(2,2,2-trifluoroethoxy)benzene97%;1,4-DI(2,2,2-TRIFLUOROETHOXY)BENZENE;1,4-Bis(2,2,2-Trifluoroethoxy)-Benzene （For Flecaintde）;Benzene, 1,4-bis(2,2,2-trifluoroethoxy)-;Flecainide Impurity 17;1,4-DI(2,2,2-TRIFLUOROETHOXY)BENZENE 66300-61-6;Flecainide Impurity 3 | | CAS: | 66300-61-6 | | MF: | C10H8F6O2 | | MW: | 274.16 | | EINECS: | 266-304-2 | | Product Categories: | | | Mol File: | 66300-61-6.mol |  |
| | 1,4-Di(2,2,2-trifluoroethoxy)benzene Chemical Properties |
| Melting point | 71-73°C | | Boiling point | 111-112°C/10mm | | density | 1.348±0.06 g/cm3(Predicted) | | storage temp. | Sealed in dry,Room Temperature | | Appearance | White to off-white Solid | | BRN | 4464913 | | CAS DataBase Reference | 66300-61-6(CAS DataBase Reference) |
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ALFA
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| | 1,4-Di(2,2,2-trifluoroethoxy)benzene Usage And Synthesis |
| Uses | 1,4-Bis(2,2,2-trifluoroethoxy)benzene is useful in ligand design for Cu-Catalyzed Coupling Reactions. | | Synthesis | Hydroquinone (1 eq), potassium carbonate (2.2 eq), and tetrabutylammonium bromide (0.1 eq) were dissolved in DMF, and 2,2,2-trifluoroethyl bromide (2.2 eq) was added. The mixture was stirred at 80 °C for 12 h. The reaction solution was quenched with water, extracted with ethyl acetate, dried over anhydrous sodium sulfate, and distilled under reduced pressure to give 1,4-Di(2,2,2-trifluoroethoxy)benzene in approximately 85% yield. |
| | 1,4-Di(2,2,2-trifluoroethoxy)benzene Preparation Products And Raw materials |
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