| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
| Email: |
han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic Acid
CAS:2375196-30-6
Purity:95%HPLC Package:250MG;1G Remarks:212141
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| Company Name: |
MQ (shanghai) Pharmaceuticals Co., Ltd.
|
| Tel: |
13761635123 |
| Email: |
1014988033@qq.com |
| Products Intro: |
Product Name:2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid , KB02-COOH
CAS:2375196-30-6
Purity:＞95% Package:1G，5G
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| Company Name: |
Jilin Province Woda Biotechnology Co., Ltd.
|
| Tel: |
13504435624 |
| Email: |
1927928688@qq.com |
| Products Intro: |
Product Name:2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid
CAS:2375196-30-6
Purity:99% HPLC Package:1g;1kg
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Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- manufacturers
- KB02-COOH
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- $297.00 / 5mg
-
2025-10-27
- CAS:2375196-30-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Basic information |
| Product Name: | Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- | | Synonyms: | Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]-;2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid;KB02-COOH;2-((1-(2-Chloroacetyl)-1,2,3,4-tetrahydroquinolin-6-yl)oxy)acetic acid , KB02-COOH | | CAS: | 2375196-30-6 | | MF: | C13H14ClNO4 | | MW: | 283.71 | | EINECS: | | | Product Categories: | | | Mol File: | 2375196-30-6.mol | ![Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Structure](CAS/20210305/GIF/2375196-30-6.gif) |
| | Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Chemical Properties |
| Boiling point | 573.3±50.0 °C(Predicted) | | density | 1.383±0.06 g/cm3(Predicted) | | solubility | DMSO: 66.67 mg/mL (234.99 mM) | | form | Solid | | pka | 3.20±0.10(Predicted) | | color | White to off-white |
| | Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Usage And Synthesis |
| Uses | KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 (HY-129917) and KB02-SLF (HY-129610)[1]. | | Biological Activity | KB02-COOH is a fragment of synthesis of ubiquitin E3 ligase ligand KB02. KB02 can be used in the synthesis of PROTAC, such as KB02-JQ1 and KB02-SLF [1]. | | IC 50 | Cereblon | | References | [1]. Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746. |
| | Acetic acid, 2-[[1-(2-chloroacetyl)-1,2,3,4-tetrahydro-6-quinolinyl]oxy]- Preparation Products And Raw materials |
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