哌替啶 基本信息
| 中文名称 | 哌替啶 |
|---|---|
| 中文同义词 | 得美樂;地露美;杜冷丁;利多尔;哌替啶;甲醇(哌替啶);哌替啶 溶液 |
| 英文名称 | MEPERIDINE |
| 英文同义词 | N-Methyl-4-phenyl-4-carbethoxypiperidine;Petantin;Pethanol;Pethidin;Pethidineter;Petydyna;Phetidine;Piperosal |
| CAS号 | 57-42-1 |
| 分子式 | C15H21NO2 |
| 分子量 | 247.33 |
| EINECS号 | 200-329-1 |
| 相关类别 | Stable Isotopes;Controlled Drug StandardsAlphabetic;M;MEA - MES |
| Mol文件 | 57-42-1.mol |
| 结构式 |  |
哌替啶 性质
| 熔点 | 270°C |
|---|---|
| 沸点 | 390.37°C (rough estimate) |
| 密度 | 1.0267 (rough estimate) |
| 折射率 | 1.5130 (estimate) |
| 闪点 | 11 °C |
| 储存条件 | −20°C |
| 酸度系数(pKa) | pKa 8.7 (Uncertain) |
| 水溶解性 | 6.55g/L(25 ºC) |
| BCS Class | 1 |
| EPA化学物质信息 | 4-Piperidinecarboxylic acid, 1-methyl-4-phenyl-, ethyl ester (57-42-1) |
安全信息
| 危险品标志 | F,T |
|---|---|
| 危险类别码 | 11-23/24/25-39/23/24/25 |
| 安全说明 | 7-16-36/37-45 |
| 危险品运输编号 | UN 1230 3/PG 2 |
| WGK Germany | 1 |
| 毒害物质数据 | 57-42-1(Hazardous Substances Data) |
| 毒性 | A narcotic analgesic used for moderate to severe pain and during obstetrical anesthesia. Its oral LD50 in rats is 170 mg/kg. It has multiple actions qualitatively similar to those of morphine, and therapy is similar to that for morphine. Advantages over morphine concerning efficacy and reduced risk of addiction were largely illusory. This, and potential drug interactions, have resulted in a dramatic reduction in use. |