|
ChemicalBook Optimization Suppliers |
|
| 化学名: | | | 英語化学名: | levomecol | | 别名: | levomecol | | CAS番号: | 118573-58-3 | | 分子式: | C16H18Cl2N4O7 | | 分子量: | 449.24272 | | EINECS: | | | カテゴリ情報: | | | Mol File: | 118573-58-3.mol |  |
| | levomecol Usage And Synthesis |
| 使用 | Levomecol (Chloramphenicol), made up of Chloramphenicol, Methyluracil, is a broad-spectrum antibiotic that is derived from the bacterium Streptomyces venezuelae. Levomecol (Chloramphenicol)) stops bacterial growth by binding to the bacterial ribosome (blocking peptidyl transferase) and inhibiting protein synthesis[1][2][3]. | | in vivo | Levomecol (solution applied on the wound for 14 consecutive days) can inhibit the infiltration of mast cells and stimulate the infiltration of lymphocytes and macrophages (monocytes) into the wound, and has antibacterial activity on rats infected with pathogens[2].
Levomecol (40% ointment solution) can effectively correct the disorder of tissue apoptosis in the occurrence of ischemic complications in rats with diabetes[3].
| | 参考文献 | [1] Chloramphenicol
[2] Babenkov HD, et al. [The influence of photochemically activated 40% solution of levomecol ointment toward apoptosis in muscles of the rats posterior extremities in inflammatory-purulent complications of diabetes mellitus]. Klin Khir. 2006 Jul;(7):58-60. Ukrainian PMID:17115602
[3] Babenkov HD, et al. [The influence of photochemically activated 40% solution of levomecol ointment toward apoptosis in muscles of the rats posterior extremities in inflammatory-purulent complications of diabetes mellitus]. Klin Khir. 2006 Jul;(7):58-60. Ukrainian. PMID:17115602 |
|