| Company Name: |
Haoyuan Chemexpress Co., Ltd.
|
| Tel: |
021-58950125 |
| Email: |
info@chemexpress.com |
| Products Intro: |
Product Name:SJB3-019A
Purity:>98% Package:3500RMB/1mg
|
| Company Name: |
MedChemexpress LLC
|
| Tel: |
021-58955995 |
| Email: |
sales@medchemexpress.cn |
| Products Intro: |
Product Name:SJB3-019A
Purity:>98% Package:1475RMB/2mg
|
SJB3-019A manufacturers
- SJB3-019A
-
- $95.00 / 1mg
-
2025-11-10
- CAS:2070015-29-9
- Min. Order:
- Purity: 99.75%
- Supply Ability: 10g
- SJB3-019A
-
- $95.00 / 1mg
-
2025-11-10
- CAS:2070015-29-9
- Min. Order:
- Purity: 99.75%
- Supply Ability: 10g
|
| | SJB3-019A Basic information |
| Product Name: | SJB3-019A | | Synonyms: | SJB3-019A;Naphth[2,3-d]oxazole-4,9-dione, 2-(3-pyridinyl)-;SJB-3-019A,SJB3 019A,SJB3019A;2-(Pyridin-3-yl)naphtho[2,3-d]oxazole-4,9-dione;SJB3-019A, 10 mM in DMSO | | CAS: | 2070015-29-9 | | MF: | C16H8N2O3 | | MW: | 276.25 | | EINECS: | | | Product Categories: | | | Mol File: | 2070015-29-9.mol |  |
| | SJB3-019A Chemical Properties |
| Boiling point | 526.1±52.0 °C(Predicted) | | density | 1.426±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: 2mg/mL, clear | | form | Solid | | pka | 2.74±0.12(Predicted) | | color | Light yellow to yellow |
| | SJB3-019A Usage And Synthesis |
| Uses | SJB3-019A is a potent and novel USP1 inhibitor, 5 times more potent than SJB2-043 in promoting ID1 degradation and cytoxicity in K562 cells with IC50 of 0.0781 μM. | | Biological Activity | potent USP1 inhibitor th at induces ID1 degradation, upregulation of p21 and cytoxicity in K562 and other leukemic cell lines | | References | [1] Helena Mistry, et al. Small molecule inhibitors of USP1 target ID1 degradation in leukemic cells. Mol Cancer Ther Published OnlineFirst October 15, 2013. DOI:10.1158/1535-7163.MCT-13-0103-T |
| | SJB3-019A Preparation Products And Raw materials |
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