| Company Name: |
Codow Chemical Co.,Ltd.
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18620099427 |
| Email: |
amy@howeipharm.com |
| Products Intro: |
Product Name:D-erythro-sphinganine-d7
CAS:1246304-35-7
Purity:>99% Package:1MG;2.5MG;5MG
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| Company Name: |
Chengdu Dianchun Technology Co., Ltd
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| Tel: |
400-1166-196 18502815961 |
| Email: |
cdhxsj@163.com |
| Products Intro: |
Product Name:D-erythro-sphinganine-d7
CAS:1246304-35-7
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:Sphinganine-d7 (d18:0)
CAS:1246304-35-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:Sphinganine-d7 (d18:0)
CAS:1246304-35-7
Purity:>95% Package:500μg;1mg
|
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| | D-erythro-sphinganine-d7 Basic information |
| | D-erythro-sphinganine-d7 Chemical Properties |
| solubility | DMF: 10 mg/mL; DMSO: 2 mg/mL; Ethanol: miscible | | form | A crystalline solid |
| | D-erythro-sphinganine-d7 Usage And Synthesis |
| Description | Sphinganine-d7 (d18:0) is intended for use as an internal standard for the quantification of sphinganine (d18:0) by GC- or LC-MS. Sphinganine (d18:0) is a precursor to ceramide and sphingosine as well as a substrate of sphingosine kinases, which generate sphinganine-1-phosphate .1 Sphinganine (d18:0) levels increase significantly in response to certain mycotoxins, including fumonisins, as well as in some cancers.2,3,4 | | References | 1. Smith, E.R., and Merrill, A.H., Jr. Differential roles of de novo sphingolipid biosynthesis and turnover in the “Burst” of free sphingosine and sphinganine, and their 1-phosphates and N-acyl-derivatives, that occurs upon changing the medium of cells in culture J. Biol. Chem. 270(32),18749-18758(1995).
2. Pruett, S.T., Bushnev, A., Hagedorn, K., et al. Biodiversity of sphingoid bases ("sphingosines") and related amino alcohols J. Lipid Res. 49(8),1621-1639(2008).
3. Shephard, G.S., van der Westhuizen, L., and Sewram, V. Biomarkers of exposure to fumonisin mycotoxins: A review Food Addit. Contam. 24(10),1196-1201(2007).
4. Yin, J., Miyazaki, K., Shaner, R.L., et al. Altered sphingolipid metabolism induced by tumor hypoxia - new vistas in glycolipid tumor markers FEBS Lett. 584(9),1872-1878(2010). |
| | D-erythro-sphinganine-d7 Preparation Products And Raw materials |
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