| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Recombinant Human IGFBP3 Protein, His Tag
Purity:>90% as determined by SDS-PAGE Package:50μg, 100μg
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| Company Name: |
Shanghai Huzhen Industrial Co., LTD
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| Tel: |
021-60345367 13916550749 |
| Email: |
sales@shzbio.com |
| Products Intro: |
Product Name:IGFBP3
Purity:> 99% Package:50ul/RMB 1098;100ul/RMB 1880;200ul/RMB 2900 Remarks:IBP3_HUMAN; Insulin-like growth factor-binding protein 3; IBP3; IBP-3; IGF-binding protein 3; IGFBP-3; IBP3; BP-53;
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| Company Name: |
Biolab Reagents
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| Tel: |
027-65279366 18108604356 |
| Email: |
products@biolabreagent.com |
| Products Intro: |
Product Name:IGFBP3
Purity:95% SDS-PAGE Package:1mg;100ug
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| | HUMAN IGFBP-3 Basic information |
| Product Name: | HUMAN IGFBP-3 | | Synonyms: | HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3;IGFBP-3;INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3;INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3, HUMAN;HUMAN IGFBP-3;IGFBP-3, HUMAN;IGF BINDING PROTEIN-3;HUMAN INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN GROWTH-HORMONE-DEPENDANT BINDING PROTEIN | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![HUMAN IGFBP-3 Structure]() |
| | HUMAN IGFBP-3 Chemical Properties |
| storage temp. | −20°C | | form | lyophilized powder | | color | white to off-white | | biological source | human |
| | HUMAN IGFBP-3 Usage And Synthesis |
| Uses | IGF-Binding Protein-3 human has been used to study its association with follicular fluid and subsequent effect on embryo development. | | Biological Activity | IGFBP3 (insulin-like growth factor-binding protein 3) is involved in cell survival as well as cell death and tumorigenesis. Epigenetic changes in IGFBP3 affect non-small-cell lung cancer, hepatocellular carcinoma, ovarian cancer, skin cancer, urological cancers, breast cancer and gastric cancer. IGFBP3 is a primary growth inhibitor and can reverse the mitogenic functions of IGF-1 (insulin like growth factor 1) by inducing apoptosis.IGFBP-3 functions both in an IGF-dependent and independent manner. Its IGF-dependent roles involve endocrine function by delivering IGFs to target cells and activating downstream signaling. Meanwhile, its IGF-independent roles include interactions with extracellular matrix and plasma membrane proteins, as well as translocation into the cytoplasm and nucleus. The C-terminal domain has cell-penetrating abilities, enabling the generation of short peptides for intracellular delivery of drugs or genes. |
| | HUMAN IGFBP-3 Preparation Products And Raw materials |
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